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PEBC Study #1

1. Top Drugs, Conditions & Pharmacology

QuestionAnswer
what is bioavailability The fraction (%) of a drug that reaches the bloodstream unchanged
what is the first-pass effect drug metabolizes in the liver before reaching circulation, decreasing bioavailability
what are "depot" IM medications drug formulated to stay in the muscle and slowly release overtime
what does it mean when a drug is lipophilic dissolves well in fats/lipids rather than aqueous/water
what does it mean when a drug is hydrophilic dissolves well in aqueous/water rather than fats/lipids
drug class of atorvastatin statins
drug class of rosuvastatin statins
drug class of pravastatin statins
drug class of simvastatin statins
Main 2 indications of statins Lowers cholesterol and Atherosclerotic cardiovascular disease (ASCVD) risk
MOA of statins they block hepatic (liver) cholesterol synthesis, and the liver pulls more LDL out of circulation.
Most notable 2side effects of statins Myalgia, rare rhabdomyolysis
Which 3 statins are affected by grapefruit Atorvastatin, Simvastatin, and Lovastatin
main 3 indication of ACE Inhibitors hypertension, heart failure, post-MI, chronic kidney disease (CKD)
drug class of ramipril ACE Inhibitors
drug class of perindopril ACE Inhibitors
drug class of enalapril ACE Inhibitors
drug class of lisinopril ACE Inhibitors
MOA of ACE Inhibitors block angiotensin I from converting into angiotensin II → less angiotensin II and less aldosterone → vasodilation and less sodium/water retention
Which cardiovascular drug classes are contraindicated in pregnancy? ACE inhibitors and ARBs
Long name for ARBs Angiotensin II Reductase Inhibitors
Most notable side effects (3) of ACE inhibitors dry cough, hyperkalemia, increased creatinine
When are ARBs generally prescribed? When ACE inhibitors are not tolerated
drug class of losartan ARBs
drug class of candesartan ARBs
drug class of valsartan ARBs
drug class of telmisartan ARBs
drug class of irbesartan ARBs
MOA of ARBs block the angiotensin II receptor → vasodilation and less sodium/water retention
Most notable side effects (2) of ARBs hyperkalemia, increased creatinine
What is creatinine? a waste product from metabolism, high levels in the blood can indicate that the kidneys are not filtering waste effectively
main 3 indications of beta blockers hypertension, angina, post-MI
drug class of metoprolol beta blockers
drug class of atenolol beta blockers
drug class of bisoprolol beta blockers
drug class of propranolol beta blockers
drug class of carvedilol beta blockers
MOA of beta blockers block beta adrenergic receptors → lower heart rate and contractility
Most notable 3 side effects of beta blockers bradycardia (slow heart rate), fatigue, dizziness
What time of day should you generally take statins bedtime
Which two body parameters are monitored while patients are on ACE inhibitors renal function and potassium
Why should you not suddenly stop taking beta blockers can cause abrupt rebound symptoms, including severe hypertension, angina and stroke
Which beta blockers are high risk for bronchospasm / bronchoconstriction? propranolol, nadolol, timolol
drug class of nadolol beta blockers
drug class of timolol beta blockers
Created by: ella.brennan
 

 



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