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Seminar
Prophylaxis of Opportunistic Infections
| Opportunistic Infection | Criteria for Screening | Primary Prophylaxis | Criteria for Discontinuing | |
|---|---|---|---|---|
| PJP | CD4 < 100 cells/mm3 CD4 < 100-200 cells/mm3 if HIV RNA level detectable | Bactrim DS or SS Daily | CD4 Count greater than or equal than 200 cells/mm3 for 3 months + | Dapsone, Atovaquone OR Dapsone + Pyrimethamine+ Leucorvorin |
| Toxoplasma gondii | Toxoplasma IgG Positive and CD4 < 100 cells/mm3 | Bactrim DS Daily | CD4 > 200 cells/mm3 for 3 months + on ART | Dapsone, Atovaquone OR Dapsone + Pyrimethamine+ Leucorvorin |
| Mycobacterium avian complex (MAC) | IF NOT TAKING ART CD4 < 50 and no active infection | Azithromycin 1200 mg Weekly | Taking Fully Suppressive ART | Azithromycin 600 mg 2 x Weekly Clarithromycin 500 mg BID |