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MOA

DrugMOA
Carbamazepine Blocks firing of action potentials presynapticallyq
Aripiprazole Partial D2 and D3 receptor agonist
Lurasidone High affinity D2, 5-HT2, and 5-HT7 receptors
Olanzipine Potent D2 and 5HT2 receptor antagonist
Quetiapine H1 antagonist, 5HT1A and 5HT2
Risperidone Potent 5HT2 antagonist weak D2
Ziprasidone 5HT2A to D2 blockade
Butalbital APAP Caffeine Inhibits phosphodiesterase, GABA receptors
Phenytoin Inhibits synaptic post tetanic potentiation
Divalproex Inhibits GABA metabolism
Lacosamide Stabilizes hyperexcitable neuronal membranes
Clobazam Potentiation due to binding in Benzo site of GABA-A
Levetiracetam facilitation of GABA-ergic inhibitory transmission
Topiramate Antagonizes the AMPA/kainite glutamate receptor
Oxcarbazepine Blockade of VG sodium channel and inhibition of repetitive neuronal firing
Phenobarbital Depress monosynaptic responses in the CNS
Lamotrigine Inhibits VG sodium channels = reduces the release of glutamate and aspartate
Lithium Alters cation transport across cell membrane
Benztropine Inhibits cholinergic and histamine receptors
Carbidopa Levodopa Increases levodopa at the BBB, crosses BBB and is converted to dopamine
Pramipexole Nonergot-derived dopamine subtype-selective agonist D2 and D3
Ropinirole Nonergloine dopamine agonist for D2
Donepezil Inhibits AChE = enhances acetylcholine
Memantine Uncompetitive NMDA receptor antagonist
Rizatriptan Selective agonist for serotonin in cranial arteries, vasoconstriction
Created by: simsm6102
 

 



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