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A&P Lecture 12

QuestionAnswer
The urinary system is also called the excretory system
US function filters blood to remove metabolic waste, toxins, and excess water, producing urine to maintain homeostasis
The urinary system consists of 2 kidneys that serve as primary excretory organs 1 urinary bladder to store urine 2 ureters connected each kidney to the bladder Urethera where liquid waste is eliminated
two kidneys filter waste from ______ and form ______ blood urine
Functions of a kidney (7) 1. Urine formation 2. Excretion 3. Regulation of blood volume an pressure 4. Regulation of blood solute concentrations 5. Regulation of extracellular pH 6. Regulation of red blood cell synthesis 7. Regulation of vitamin D synthesis
Urine is composed of excess water, excess ions, metabolic waste, and toxins
Kidney anatomy Two bean-shaped organs located flanking the last thoracic (T12) to the third lumbar (L3) vertebrae Each kidney is around the size of a fist, 130 grams
The renal artery and nerves enter the kidney at the hilum, the concave medial aspect of the kidney
The renal vein and ureter also exit at the kidney at the hilum
The kidneys are organized into 2 major regions: Renal cortex = superficial Renale medulla = deep
The cortex is the location for the blood-filtering structures of the kidneys
The medulla is composed of many cone-shaped structures called renal pyramids, whose bases project into the cortex
Renal papilla the medullary tip of pyramid
Renal columns are extensions of cortical tissue between each pyramid
Renal sinus is the fat-filled cavity in the middle of the kidney that cushions important parts. Here a set of tubes collects the urine for movement to the urinary bladder
The nephrons are the functional unit of the kidney
A nephron is composed of 2 major parts Glomerular capsule (or Bowman's capsule) Renal tubule Many nephrons then connect to a shared collecting duct
3 Steps in nephron function 1. Glomerular filtration 2. Tubular reabsorption and secretion 3. Water conservation
Glomerular filtration Here is where blood enters to be filtered. High osmotic pressure and high concentration of solutes in blood allows water and solutes to leave the blood and enter the capsule. This liquid that enters the nephron is called glomerular filtrate
Glomerulur filtration (GFR) is a blood test that determines how much blood passes through these filters each minute
Tubular reabsorption and secretion water and solutes (Na, K, Cl, glucose, amino acids) are reabsorbed from tubule into capillaries. Conversely, metabolic waste and other produces from the blood are secreted into the tubule
Water conservation concentration of urine at collecting duct through reabsorption of water
Glometrular filtration rate (GFR): determines how much blood passes through glomerulus GFR is very stable and does not significantly change even when there is a larger change of blood pressure.
GFR of individuals varies by age, sex, and race
GFR is determined by comparing values of serum proteins such as ______ and _______ (a waste product of muscle activity) between blood and urine albumin creatine
Healthy GFR Values below 120/min. 90 are abnormal
Values under _____ indicates kidney failure and require hemodialysis 15ml/min
Hemodialysis using an external machine as a kidney to filter blood
How hemodialysis works your entire blood is circulated outside your body in a machine placed outside the body known as a dialyzer. This dialyzer acts like an artificial kidney that cleans and returns the blood to your body. This is done either at a facility or at home.
Hemodialysis is an alternative to kidney replacement or a temporary treatment for those awaiting a kidney. Generally require a 4 hour visit 3 times a week.
KT Pros Patients can lead a more normal life without having to watch what they eat and drink Cheaper for the NHS overall Much longer life expectancy
KT Con Must take immunosuppressant drugs which increase the risk of infection Shortage of organ donors Kidneys only last 8-9 ears Any operation carries a risk
KD Pro Available to all kidney patients No need for immuno suppressant drugs
KD Con Patients must limit their salt and protein intake between dialysis sessions Expensive for the NHS Regular dialysis appointments affects the patient’s life style
Created by: liladdoyle
 

 



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