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Cardio 3 and 4
| Question | Answer |
|---|---|
| dabigatran | Pradaxa |
| apixaban | Eliquis |
| rivaroxaban | Xarelto |
| warfarin | Coumadin |
| warfarin | Jantoven |
| enoxaparin | Lovenox |
| heparin | ---- |
| clopidogrel | Plavix |
| ticagrelor | Brilinta |
| aspirin | Bayer |
| aspirin other notes | Bufferin Ecotrin |
| nitroglycerin | Nitrostat |
| alteplase | Cathflo Activase |
| What is the direct thrombin inhibitor? | dabigatran |
| Which ONE medication can be used for PAD?? That's peripheral artery disease | rivaroxaban |
| What is the anticoagulant and vitamin K antagonist? | warfarin |
| What is the plain jane anticoagulant? | heparin |
| What medication can be used for CAD and stoke? | clopidogrel |
| what medication is ONLY for ACS? | ticagrelor |
| what is the vasodilator? | nitroglycerin, Nitrostat |
| amiodarone | Pacerone Nexterone |
| ezetimibe | Zetia |
| fenofibrate | Tricor Trilipix |
| gemfibrozil | Lopid |
| atorvastatin | Lipitor |
| lovastatin | Altoprev |
| pravastatin | Pravachol |
| rosuvastatin | Crestor IMPORTANT |
| simvastatin | Zocor |
| omega-3 ethyl esters | Lovaza |
| icosapent ethyl | Vascepa |
| What are the medications indicated for hypertriglyceridemia? | Fibric acid derivative Omega-3 fatty acids |
| amiodarone indications | AF (rhythm control) ventricular fibrillation ventricular tachycardia |
| what medications should you avoid excessive grapefruit juice intake and should avoid during pregnancy and breastfeeding? | HMG-CoA reductase inhibitors STATINS |
| Which medication is intended only for life-threatening arrhythmias; pulmonary toxicity, hepatoxicity; proarrhythmic? | amiodarone/ Pacerone, Nexterone |
| why does amiodarone cause epithelial keratopathy and photosensitivity? | Amiodarone (Amiodarone) causes epithelial keratopathy because it deposits in corneal epithelial cells (lipid-rich drug accumulation), forming microdeposits. It causes photosensitivity because the drug absorbs UV light and generates reactive oxygen species, leading to skin damage. |
| amiodarone has this really cool side effect about the thyroid what is it? | hypothyroidism, hyperthyroidism |
| What kind of weird lab value can taking a STATIN cause? | hepatic transaminases |
| What medication has the potential to cause skin necrosis | rivaroxaban / Xarelto |
| what is the US BBW of warfarin? also its a NTI what does that mean? | bleeding risk Narrow therapeutic index drug and therapeutic monitoring is recommended with INR |
| what are the special notes for dabigatran? | dabigatran is DIRECT she swallows whole and gets rid of them after 4 months. Direct thrombin inhibitor Swallow whole dispense and store in original package- discard 4 months after opening |
| Which medication has a BBW for reduced effectiveness in PM? | clopidogrel/Plavix |
| which medication has a BBW for significant sometimes fatal bleeding; do not exceed aspirin greater than 100 mg daily due to reduce effectivness? | Ticagrelor |
| Which medication is CI in children with viral infections? | aspirin |
| which medication has in the notes "do not use with a PDE-inhibitors TACHYPHYLAXIS and can aggravate angina caused by hypertrophic cardiomyopathy | nitroglycerin |
| how do the nitroglycerin side effect happen? | Do not use with PDE-5 inhibitors (e.g., sildenafil): both increase cGMP, causing massive vasodilation → severe hypotension. Tachyphylaxis: continuous exposure depletes sulfhydryl groups needed to generate nitric oxide, so the drug effect rapidly decreases. Can worsen angina in hypertrophic cardiomyopathy: it reduces preload, which worsens left ventricular outflow obstruction, decreasing cardiac output and coronary perfusion. |
| what is tachyphyaxis | Tachyphylaxis is a rapid decrease in a drug’s effect after repeated or continuous use, even if the same dose is given. |