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STS 650 chapter 9
Meds that affect Coagulation
| Question | Answer |
|---|---|
| What is a thrombolytic? | agents used to help to speed the breakdown of EXISTING blood clots |
| Does blood contain BOTH coagulants and anticoagulants? T or F | True |
| Name 3 stages of clot formation and describe | Thromboplastin is formed, Thromboplastin converts prothrombin into thrombin, and Thrombin converts fibrinogen to fibrin |
| Clotting that takes place in a broken blood vessel is a thrombus, T or F? | False |
| What are coagulants? | Drugs that promote or accelerate, or make possible blood coagulation |
| T or F Hemostatics are agents that decelerate blood clots at a surgical site | False |
| Gelatin hemostats can ONLY be used when moistened with saline | False |
| Give an example of a gelfoam used in an otologic surgery, what is the name of it? | pledgets |
| Name 2 "flowable " types of absorbable gelatin | Floseal and Surgiflow |
| Absorbable sponges are made from purified bovine collagen T or F | True |
| Avitene Microfibrillar Collagen Hemostat (MCH) is a wet preparation of porcine collagen. T or F | False |
| What leads to the formation of a fibrin clot when applying an MCH? | Direct pressure |
| Avitene available in a powder form called "flour" T or F | True |
| Surgicel is absorbable and bactericidal. T or F | True |
| How is thrombin measured? | in units |
| Thrombin is an enzyme that helps start the cascade of blood-clotting. T or F | True |
| Name 3 ways thrombin can be applied | Topically in a solution, powder, in combination with a gelatin sponge |
| What are 2 examples of a fibrin SEALANT? | Tisseel and Evicel |
| Freeze dried thrombin examples are Surgiflo and Floseal. T or F | True |
| What is bone wax made from? | Bees wax |
| Bone wax is used as a matrix for clotting? T or false | False |
| Name 2 ways that bone wax is applied | Gloved fingers and on an instrument |
| Tannic acid is made from animal collagen. T or F | False |
| Name a surgery that tannic acid is used? | Tonsillectomy |
| Silver nitrate is safe to use around the eyes. T or F | False |
| Silver nitrate can cauterize wounds and removes warts. T or f | True |
| Name the brown mixture of ferrous sulfate, sulfuric acid, and nitric acid diluted with water. | Monsel's solution |
| What are the 2 blood factors missing if one is a hemophiliac? | VIII and IX |
| Define anticoagulant | drugs that prevent or interfere with blood coagulation |
| Anticoagulants dissolve formed clots. T or F | False |
| Anticoagulants are used in surgery to help prevent clot formation as a response to trauma or manipulation of blood vessels. T or F | True |
| Name 3 ways Parental drugs are administered | IV, subq, and topically |
| What is the primary anticoagulant used intraoperatively in peripheral and cardiovascular procedures? | Heparin |
| Heparin can be administered directly into the affected artery through an irrigating catheter to clear out debris. Tor F | True |
| The antagonist for Heparin is Coumarin. T or F | False |
| Are oral anticoagulants ok to use in an emergency situation? | No |
| What is the antedote for excessive Warfarin? | Vitamin K |
| Fresh frozen plasma (FFP) can be administered in emergency situations. Tor F | True |
| Aspirin is considered an anticoagulant. T or F | True |