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CNS medications
CNS
| Generic | Brand | Class/Category | Receptor activity |
|---|---|---|---|
| Carbemazepine | Tegretol | Na+ Channel Inhibition | |
| Eslicarbazepine | Aptiom, | Na+ Channel Inhibition | |
| Oxcarbazepine | Trileptal | Na+ Channel Inhibition | |
| Lacosamide | Vimpat | Na+ Channel Inhibition | |
| Lamotrigine | Lamictal | Na+/ Ca2+ Channel inhibition | |
| Phenytoin | Dilantin | Na+ Channel Inhibition | |
| Topiramate | Topamax | Na+/GABA/misc Channel Inhibition | |
| Valproic Acid | Depakote/Depakene | Na+/Ca2+/GABA Channel Inhibition | |
| Zonisamide | Zonegran | Na+/Ca2+/Misc Channel Inhibition | |
| Cenobamate | Xcopri | Na+/GABA Channel Inhibition | |
| Ethosuximide | Zarontin | Ca2+ channel inhibition | |
| Gabapentin | Neuronin | Ca2+ channel inhibition | |
| Pregabalin | Lyrica | Ca2+ channel inhibition | |
| Phenobarbital | Luminal | GABA Enhancement | |
| Primidone | Mysoline | GABA Enhancement | |
| ALL Benzodiazepines | GABA Enhancement | ||
| Tigabine | Gabitril | GABA Enhancement | |
| Vigatrin | sabril | GABA Enhancement | |
| Dihydroergotamine | Migranol | ||
| Ergotamine | Ergomar | ||
| Sumatriptan/Naproxen | Treximet | ||
| Zolmitriptan | Zomig/ZMT | ||
| Rizatriptan | Maxalt/MLT | ||
| Frovatriptan | Frova | ||
| Almotriptan | Axert | ||
| Eletriptan | Relpax | ||
| Naratriptan | Amerge | ||
| Asprin, Butalbitol, Caffeine | Florinal | ||
| Tylenol, Butalbitol, Caffeine | Fioricet | ||
| Butorphenol (nasal spray) | Stadol | ||
| Lasmiditan | Reyvow | ||
| Ubrogepant | Ubrelvy | ||
| Rimegepant | Nurtec | ||
| Zavegepant | Zavzpret | ||
| Erenumab | Aimovig | ||
| Fremanezumab | Ajovy | ||
| Galcanezumab | Emgality | ||
| Eptinezumab | Vyepti | ||
| Atogepant | Quilipta | ||
| Sumatriptan | Imitrex | ||
| Fluvoxamine | Luvox | SSRI | SERT |
| Fluoxetine | Prozac | SSRI | SERT, 5HT2 |
| Paroxetine | Paxil | SSRI | SERT, NET, m1, a1 |
| Citalopram | Celexa | SSRI | SERT |
| Sertraline | Zoloft | SSRI | SERT |
| Vortioxetine | Trintellix (Atypical Antidepressants) | SSRI, 5-HT1a presynaptic autorecptor and post synaptic agonist | SERT, NET |
| Venalfaxine/dessvenlafaxine | Effexor/prestiq | SNRI | SERT>>NET |
| Duloxetine | Cymbalta | SNRI | SERT, NET |
| Milnacipran | Savella | SNRI | SERT<<NET |
| Levomilnacipran | Fetzmia | SNRI | SERT<<NET |
| Amoxapine | - | TCA (blockade of receptor) | 5HT-2 has highest potency |
| Dozepin | Silenor | TCA (blockade of receptor) | H1, a1 have highest potency |
| Imipramine | Tofranil | TCA (blockade of receptor) | SERT, M1 have highest potency |
| Desipramine | Norpramin | TCA (blockade of receptor) | NET has highest potency |
| Clomipramine | Anafranil | TCA (blockade of receptor) | SERT has highest potency |
| Amitriptyline | Elavil | TCA (blockade of receptor) | M1, a1 has highest potency |
| Nortriptyline | Pamelor | TCA (blockade of receptor) | NET has highest potency |
| Buproprion | Wellbutrin SR/XL, Zyban | DNRI | DAT>>>NET |
| Buproprion + DXM | Auvelity | DNRI and NMDA receptor antagonist. Sigma-1 receptor agonist | |
| Gepirone | - | Atypical Antidepressants | |
| Trazadone | Deseryl | Atypical Antidepressants | |
| Vilazodone | Viibryd | Atypical Antidepressants | |
| Mirtazapine | Remeron | Atypical Antidepressants | 5HT2/3, H1, a2 |
| Isocarboxazid | Marplan | MAOI | Inhibit MOA-A and MOA-B |
| Phenelzine | Nardil | MAOI | Inhibit MOA-A and MOA-B |
| Selegline Patch | Ensam | MAOI | Inhibit MOA-A at high doses and MOA-B at normal doses |
| Tranylcypromine | Parnate | MAOI | Inhibit MOA-A and MOA-B |
| Lorazepam | Ativan | BZD | |
| Oxazepam | Serax | BZD | |
| Alprazolam | Xanax | BZD | |
| Chlordiazepoxide | Librium | BZD | |
| Clonazepam | Klonipin | BZD | |
| Diazepam | Valium | BZD | |
| Methylphenidate | Concerta | ||
| Methylphenidate | Aptensio-XR | ||
| Methylphenidate | Daytrana | ||
| Methylphenidate | Quillivant XR/Quillichew ER | ||
| Methylphenidate | Cotempla XR-ODT | ||
| Methylphenidate | Jornay PM | ||
| Amphetamine | Adderall | ||
| Amphetamine | Aszenys XR-ODT/ER | ||
| Amphetamine | Dyanavel XR | ||
| Amphetamine | Mydayis | ||
| Amphetamine | Evekeo | ||
| Disulfram | Antabuse | Inhibit ADH | |
| Acamprosate | Campral | GABA agonist, NMDA antagonist | |
| Nalmefene | Opvee | Opioid use mitigtion | |
| Buprenorphine | Buprenex | Opioid use mitigtion | |
| L-Dopa + Carbidopa | Sinemet | ||
| Foslevodopa + Foscarbidopa | Vyalev |
Created by:
Danielle9685