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Toxicology

med emergenceis

QuestionAnswer
any substance whose chemical action can damage body structures or impair body function poison
poisonous substance produced by bacteria, animals, plants, or any chemical that causes adverse effects on an organism Toxin
4 routes of poison entrance to the body ingestion, inhalation, absorption, injection
most common route of poisoning ingestion
what are some ways to prevent absorption of poison ? cathartics, gastric lavage, activated charcoal
poison help line 1-800-222-1222
what is in a cyanokit and what is it used for? hydroxocobalamin Adult 5g over 15min max of 10 and pedi 70mg/kg max of 5 over 15min
treatment sequence for beta blocker overdose glucagon 3-10mg IVP followed by 3-5mg/hr infusion calcium chloride 0.5-1g
treatment for calcium channel blocker overdose calcium chloride 1-2g followed by infusion 1-2g/hr Glucagon 3-10mg IVP followed by 3-5mg/hr
treatment of TCA overdose for adult and pedi Adult: Sodium bicarb 8.4% 1mEq/kg pedi: 4.2% Sodium bicarb 1mEq/kg
what is a typical symptom of salicylate overdose tinnitus
why do we treat sympathomimetics, specifically cocaine and caffeine with sodium bicarb and benzos they can act as sodium channel blockers and it's overactivation of sympathetic system so benzos help depress the CNS by increasing inhibitory GABA
why do we treat cholinergic overdose with atropine and pralidoxime atropine is an anticholinergic and pralidoxime reactivates AChE
anticholinergic overdoses are treated with physostigmine
inhibits cytochrome c oxidase in the electron transport chain from accepting oxygen - can't use oxygen at cellular level to make ATP cyanide
how do you treat lithium overdose activated charcoal doesn't work, Sodium Bicarb, mannitol, hemodialysis
atropine, Benadryl, jimsonweed, and amitriptyline (TCA) = are all what kind of agents? Anticholinergic
DUMBBBELSSS stand for? Diarrhea, Urination, Miosis, Bronchorrhea, Bradycardia, Bronchospasm, Emesis, Lacrimation, Seizure, salivation, sweating
Created by: Lindsey.George
 

 



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