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anatomy test 2
part 3
| Question | Answer |
|---|---|
| know the basic parts of the large intestine. what is the order from proximal to distal? | cecum- a pouch connected to the junction of the small and large intestines appendix ascending colon transversal colon descending colon sigmoid colon - s-shaped portion that becomes the rectum anal canal |
| what are the flexures? | -bends or curves in the large intestine that help facilitate the movement of waste hepatic flexure- between ascending and transverse colon splenic flexure- between transverse descending colon -assist in efficient passage of fecal matter through colon |
| what are the basic steps of digestion of proteins? | -broken down to peptides by pepsin (stomach) -broken down to peptides by trypsin and chymotrypsin in small intestine (pancreatic enzymes) -amino acids are absorbed via the small intestine -transported to liver |
| what are the basic steps of digestion of carbohydrates? | -amylose/starch is broken down to disaccharides by the brush border enzymes and pancreatic amylase -SI brush border enzymes break disaccharides down to monosaccharides -monosaccharides are absorbed via the small intestine -transported to liver |
| what are the basic steps of digestion of nucleic acids? | -DNA and RNA are degraded to nucleotides by pancreatic DNA-ase and RNA-ase nucleotides are broken down to pentose by SI brush border enzyme (nucleotideases) -absorbed via the small intestine -transported to the liver |
| what are the basic steps of digestion of lipids? | |
| how does each digestion process get to the liver? | via the superior mesenteric vein and hepatic portal vein |
| what is the function of the superior mesenteric vein? | -drains blood from the small intestine and parts of the large intestine. -collects nutrient-rich blood from several smaller mesenteric veins -transports blood to the hepatic portal vein for processing by the liver. |
| what are some of the functions of the liver? | digestive function-bile production- bile salts facilitate emulsification of fat to allow efficient lipase action -carbohydrate, lipid, protein metabolism -synthesis of blood proteins -stores iron as ferritin -detoxification- alcohol, toxins, drugs |
| what are some properties of the liver? | -encased by the ribs and attached to the diaphragm -larger right lobe, smaller left lobe -hepatic portal vein- delivers nutrient rich blood to the liver via the s and i mesenteric veins -hepatic artery- carries 02 rich blood to the liver |
| what are some properties of the liver (bile carrying ducts) ? | -the right and left hepatic ducts carry bile from the liver and merge to form common hepatic duct- merges with the cystic duct to form common bile duct cystic duct carries to the gall bladder for storage common bile duct delivers to the duodenum |
| blood flow in and out of the liver. | blood enters hepatic lobule (functional unit of liver) via branches of portal vein + hepatic arteries -flows through sinusoid vessels and hepatocytes (cells) + absorb nutrients -blood exits lobule via central vein and exits liver via hepatic vein |
| what kinds of products does the pancreas produce? | digestive enzymes amylase- breaks down carbohydrates lipase- breaks down fats nucleases break down DNA and RNA proteases- break down proteins (trypsin, chymotrypsin, carboxypeptidase) |
| how are the proteases from the pancreas activated? | proteases are synthesized as inactive precursors-> zymogens (trypsinogen) in pancreas zymog. are secreted duodenum intestinal enteropeptidase makes trypsinogen -> trypsin trypsin makes EZ into active forms and protein is broken down to peptides and AA |
| how is fecal matter ejected from the anus? | mass movements move feces into rectum + there is urge to defecate controlled via defecation reflex muscles of sigmoid colon + rectum contract in peristalsis internal sphincter relax voluntary relaxation of external anal sphincter valsalva maneuver |
| what is the valsalva maneuver? | last step in how fecal matter is ejected from anus -deep breath and close epiglottis to increase lung pressure -contract abdominal muscles -abdominal pressure is up -feces are expelled |
| what is defecation reflex? | - is triggered when the rectum fills with stool, activating stretch receptors. -these receptors send signals to the spinal cord and brain, indicating the need to defecate |
| what are kupffer cells? | specialized macrophages (type of white blood cell that engulf and digest pathogens, dead cells, and debris) located in the liver. - filter pathogens from the blood -phagocytize bacteria and work out RBC's |
| what is the name of an inactive enzyme? | zymogen |
| what is pepsinogen? | inactive enzyme, precursor to pepsin (which breaks down proteins into mostly peptides) |
| what are the teniae coli? | -3 bands of longitudinal muscle in the large intestine -on the outside of the ascending, transverse and descending colon |
| what is hepatopancreatic ampulla? (ampulla of Vater) | - located where the bile duct + pancreatic duct converge + empty into duodenum -surrounded by sphincter of Oddi, which controls the release of digestive fluids regulates bile and pancreatic juice flow into the small intestine |
| is chemical digestion the only type of food digestion? | -no, food can also be mechanically broken down through segmentation and peristalsis. |
| what is the enterogastric reflex? | -inhibits stomach -occurs when small intestine detects food or acid - inhibits gastric movements and secretion to slow down digestion helps prevent overload of the small intestine with chyme mediated by neural and hormonal signals from intestines |
| what is the gastroesophageal sphincter? | -a muscular ring at the junction of the esophagus and stomach -prevents the backflow of stomach contents into the esophagus. |
| what are the three phases of gastric secretion? | 1. cephalic phase - smell/see food etc your stomach starts getting ready and produces acids 2. gastric phase- food enters stoma. enhancing secretion -> chemical signals. 3. intestinal phase- chyme enters SI, regulating secretion to prevent overload. |
| what is sterlobilin? | Sterlobilin is a brown pigment formed from the breakdown of bilirubin in the intestines. It is primarily responsible for the brown color of feces |
| what chemical gives urine its color? | Urochrome is a pigment responsible for the yellow color of urine. It is produced from the breakdown of hemoglobin in red blood cells. |
| what is secretin? | digestive hormone that stimulates liver to produce bile pancreas to release HCO3 |
| what is CCK | cholecystokinin digestive hormone that stimulates pancreas to release enzymes gall bladder to eject bile satiety |
| what is intrinsic factor? | a substance secreted by the stomach (pariteal) which enables the body to absorb vitamin B12 |
| what is pernicious anemia? | an autoimmune condition that prevents your body from absorbing vitamin B12. Without adequate vitamin B12, you have fewer red blood cells carrying oxygen throughout your body. |