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ID 4
| Cateogry | Generic | Brand | Indications | Clasification | EK |
|---|---|---|---|---|---|
| Allylamine antifungal | terbinafine (PO,topical) | Lamisil | Onychomycosis | Topical: OTC | Key Side Effects: nausea, abdominal pain, diarrhea, elevated hepatic transaminases, headache |
| Azole antifungal | fluconazole (PO,IV) | Diflucan | Vuvovaginal candidiasis, oropharyngeal candiddiasis, invasive candidiasis | Key Side Effects: nausea, abdominal pain, diarrhea, QTc prolongation, elevated hepatic transaminases | |
| Azole antifungal | ketoconazole (PO,topical) | Nizoral | Tinea infections | Topical: OTC | Key Side Effects: nausea, abdominal pain, diarrhea, QTc prolongation, increased hepatic transaminases |
| Polyene antifungal | nystatin (PO) | nystatin | Oropharyngeal candidiasis | Key Side Effects: phlebitis, diarrhea, vomiting, anemia, fever | |
| Polyene antifungal | nystatin (Topical) | Nystop | Cutaneous and mucocutaneous fungal infections | Key Side Effects: burning, itching Other Notes: only use oral solutions for thrush | |
| Echinocandin antifungal | micafungin (IV) | Mycamine | Invasive candidiasis | Key Side Effects: no major side effects | |
| Glucocorticoid and azole antifungal | betamethasone and clotrimazole (Topical) | Lotrisone | Cutaneous fungal infections | Key Side Effects: burning, itching, dryness, skin atrophy Other Notes: do not use for diaper dermatitis; adrenal suppression with long-term use over large areas of skin | |
| Neuraminidase inhibitor antivirial | oseltamivir (PO) | Tamiflu | Influenza | Key Side Effects: nausea, vomiting, neuropsychiatric events (i.e., confusion, delirium, hallucinations) in pediatric patients (rare) | |
| Antiviral | acyclovir (PO,IV) | Zovirax | Herpes simplex virus | Key Side Effects: nausea, increased hepatic transaminases, crystalluria Other Notes: vesicant | |
| Antiviral | valacyclovir (PO) | Valtrex | Herpes simplex virus | Key Side Effects: nausea, increased hepatic transaminases | |
| Antiviral | nirmatrelvir + ritonavir (PO) | Paxlovid | Covid-19 | Key Side Effects: diarrhea, dysgeusia US Boxed Warning: significant drug interactions; strong CYP3A inhibitor | |
| Antiviral | remdesivir (IV) | Veklury | Covid-19 | Key Side Effects: hyperglycemia, renal impairment, bradycardia, increased liver enzymes, hypersensitivity | |
| Nucleoside/Nucleotide Reverse Transcriptase Inhibitor (NRTI) | emtricitabine + tenofovir disoproxil fumarate (PO) | Truvada | HIV Infection, PreP, PEP | Key Side Effects: decreased bone mineral density, kidney injury, nausea, diarrhea US Boxed Warnings: post treatment acute exacerbation of hepatitis B, risk of drug resistance with use for preexposure prophylaxis | |
| Nucleoside/Nucleotide Reverse Transcriptase Inhibitor (NRTI) and integrase strand transfer inhibitor (INSTI) | emtricitabine (NRTI) + tenofovir alafenamide (NRTI) + bictegravir (INSTI) | Biktarvy | HIV infection | Key Side Effects: increased serum bilirubin, headache, weight gain, insomnia, diarrhea, nausea |