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Chapter 22

QuestionAnswer
Functions of Repiratory System (7) 1) gas exchange 2) moves air to and from lungs 3) protects respiratory surfaces from outside enviroment 4) Produces sounds 5) participates in olfactory sense 6) acid-baase balance 7) formation of angiotensin II
Anatomically respiratory system is divided into (2) - Upper respiratory system - Lower respiratory system
Upper respiratory system (3) above larynx: - Nose - Nasal Cavity - Pharynx
Lower respiratory system (5) below larynx: - Trachea - Bronchial tree - Respiratory bronchioles - Aveolar duct - Aveoli
Physiologically respiratory system is divided into (2) - Conducting Zone - Respiratory Zone
Conducting zone (5) - Nasal Cavity - Pharynx - Larynx - Trachea - Bronchial tree
Respiratory zone (4) - Respiratory bronchioles - Alveolar ducts - Alveolar sacs - Alveoli
Bronchial tree (4) - Primary bronchi - Secondary bronchi - Tertiary bronchi - Terminal bronchioles
Alveoli Air-filled pockets within the lungs where gas exchange takes place
External strucutre of nose (6) - root - bridge - dorsum nasi - apex - ala - external nasal aperture (nostrils)
Openings of nasal cavity (3) - external nasal aperature, or nostrils leads to nasal vestibule - internal nasal aperature or choanae - Paranasal sinuses
Medial wall of nasal cavity also known as nasal septum: divides nasal cavity into left and right
Nasal septum made of (2) - bone - cartilage
Lateral wall of the nasal cavity (2) - Lateral masses of the ethmoid - Inferior choncha and meatus
Roof of the nasal cavity (olfactory region) cribriform plate of the ethmoid
Floor of the nasal cavity (2) - hard palate - soft palate
Lining of the nasal cavity (2) - olfactory mucosa - respiratory mucosa
olfactory mucosa (2) - covers roof and superior chonchae - contains olfactory receptors
respiratory mucosa (2) - pseudostratified columnar ciliated epithelium - goblet cells
Nasal cavity functions (4) - Air passage - Conditions air - Olfaction - Phonation
how does the nasal cavity conditions air (3) - filters - humidifies - warms
Pharynx (2) - A chamber shared by digestive and respiratory systems - Extends from internal nares to entracnes to larynx and esophagus
Pharynx divided into three parts - nasopharynx - oropharynx - laryngopharynx
Nasopharynx (2) - Internal nares to soft palate - Pseudostratified columnar ciliated epithelium
Related structures to nasopharynx (2) - Pharyngeal tonsils - Openings to left and right auditory tubes
Oropharynx (2) - Soft palate to the level of the hyoid bone - Stratified squamous epithelium
Related structures to oropharynx (3) - Fauces - Palatine tonsils – between palatine arches - Lingual tonsils
Laryngopharynx (3) - Level of the hyoid bone to cricoid cartilage - Stratified squamous epithelium - Opens anteriorly to the larynx and inferiorly to esophagus
Cartilages of the larynx (2) - Three large, unpaired cartilages - Three small, paired cartilages
Three large, unpaired cartilages - Thyroid cartilage - Cricoid cartilage - Epiglottis
Three small, paired cartilages - Arytenoid cartilages - Corniculate cartilages - Cuneiform cartilages
Thyroid and cricoid cartilages support and protect (2) - The glottis - The entrance to trachea
During swallowing (3) - The larynx is elevated - The epiglottis folds back over glottis - Prevents entry of food and liquids into respiratory tract
Corniculate and arytenoid cartilages function in (2) - Opening and closing of glottis - Production of sound
Ligaments of the larynx (2) - Vestibular ligaments - Vocal ligaments
Vestibular ligaments and vocal ligaments (2) - Extend between thyroid cartilage and arytenoid cartilages - Are covered by folds of laryngeal epithelium that project into glottis
Epithelium of vocal ligaments and vocal ligaments (2) - Stratified squamous on and above vocal ligaments - Pseudostratified columnar ciliated below vocal ligaments
The vestibular ligaments lie within folds to protect the vocal folds
Sound production (3) - Air passing through glottis - Vibrates vocal folds - Produces sound waves
Sound is varied by (2) - Tension of vocal folds - Force of air moved
The larynx is associated with (2) - Extrinsic muscles - Intrinsic muscles
Extrinsic muscles of larynx (2) - Neck - Pharynx
Intrinsic muscles (2) - Control vocal folds - Open and close glottis
Innervation of the larynx (2) - Superior laryngeal nerve - Recurrent laryngeal nerve
Superior Laryngeal Nerve (2) - Internal - External
Recurrent Laryngeal Nerve (2) - Left: loops around aortic arch - Right: loops around subclavian artery
Sensory Innervation of Larynx (2) - Above the vocal cords - Below the true vocal cords
Sensory Innervation of Larynx, above the vocal cords Internal laryngeal
Sensory Innervation of Larynx, below the true vocal cords Recurrent laryngeal nerve
Innervation of Intrinsic Laryngeal Muscles (2) - Criothyroid muscle - All other muscles
Innervation of Intrinsic Laryngeal Muscles, Criothyroid muscle External laryngeal nerve
Innervation of Intrinsic Laryngeal Muscles. All other muscles Recurrent laryngeal nerve
The Trachea (2) - Extends from C5 to T5-7 (9-15cm in length) - 15-20 "C" shaped cartilages with trachealis muscle
Layers of trachea inner to outer (4) - Mucosa - Submucosa - Cartilage/trachealis muscle - Adventitia
The Primary Bronchi's (2) - Right and Left Primary Bronchi - Seperated by an internal ridge (carina)
Right primary bronchi (2) - 2.5 cm long, 15 mm wide - Descends at a steeper angle
Left primary bronchi (2) - 5 cm long, 13mm wide - More horizontal
Bronchial division 2 Primary (main) → 2-3 Secondary (lobar) → 8-10 Tertiary (segmental)
Walls of primary, secondary, and tertiary bronchi (3) - Contain progressively ↓ cartilage and ↑ smooth muscle - Increased smooth muscle tension affects airway constriction and resistance - Epithelium changes – pseudostratified to simple columnar
Bronchioles (3) - Each tertiary bronchus branches into multiple bronchioles - Bronchioles branch into terminal bronchioles - One tertiary bronchus forms about 6500 terminal bronchioles
Bronchioles Structure (3) - Have no cartilage - Are dominated by smooth muscle - Epithelial changes – simple columnar to simple cuboidal
Alveolar Ducts and Alveoli (3) - Respiratory bronchioles are connected to alveoli along alveolar ducts - Alveolar ducts end at alveolar sacs - Each alveolus has an extensive network of capillaries
Alveolar primary cell types (3) - Pneumocytes type I - Alveolar macrophages - Pneumocytes type II
Epithelium of pneumocytes type I simple squamous epithelium
pneumocytes type II produce surfactant
surfactant (2) - Is an oily secretion containing phospholipids and proteins - Coats alveolar surfaces and reduces surface tension
Three Layers of the Respiratory Membrane 1. Squamous epithelial cells lining the alveolus 2. Endothelial cells lining an adjacent capillary 3. Fused basement membranes between the alveolar and endothelial cells
Fissures of lungs (2) - Right has 2 (horizontal and oblique) - Left has 1 (oblique)
Hilum of lungs Where pulmonary nerves, blood vessels, lymphatics enter lung
Root of lungs Complex of connective tissues, nerves, and vessels in hilum
Surfaces of lungs (3) - Costal - Mediastinal - Diaphragmatic
Lobes of lungs (2) - Right has 3 (superior, middle and inferior) - Left has 2 (superior and inferior)
Segments of lungs (Bronchopulmonary Segments) (2) - Right lung has 10 - Left lung has 8 or 9
Blood supply of lungs consist of two sources 1. Pulmonary artery 2. Bronchial artery
The Pleura consists of (4) - Two layers: 1. Parietal pleura 2. Visceral pleura - Pleural cavity -Pleural fluid
Pleural fluid lubricates space between parietal pleura and visceral pleura
Pulmonary Ventilation the physical movement of air in and out of respiratory tract which depends upon pressure gradient
Atmospheric pressure (2) - The weight of air - Normal atmospheric pressure = 1 atm = 760 mm Hg
Pulmonary Ventilation provides alveolar ventilation
Pulmonary Ventilation is by the expansion or contraction of diaphragm or rib cage volume
Volume changes create changes in pressure as governed by Boyles law (P = 1/V)
Pressure Changes during Inhalation and Exhalation can be measured Inside (intrapulmonary) or outside the lungs (atmospheric)
Intrapulmonary Pressure (intra-alveolar pressure) Is relative to atmospheric pressure
In relaxed breathing, the difference between atmospheric pressure and intrapulmonary pressure is small, about -1 mm Hg on inhalation or +1 mm Hg on exhalation
Maximum straining, a dangerous activity, can increase range from -30 mm Hg to +100 mm Hg
The Intrapleural Pressure Pressure in space between parietal and visceral pleura
The Intrapleural Pressure averages, maximum and remains - Averages −4 mm Hg - Maximum of −18 mm Hg - Remains below atmospheric pressure throughout respiratory cycle
Injury to the Chest Wall (2) Pneumothorax - Atelectasis
Pneumothorax allows air into pleural cavity
Atelectasis (also called a collapsed lung) is a result of pneumothorax
The Respiratory Cycle - Single cycle of inhalation and exhalation - Tidal Volume (VT) - Inhalation - Exhalation
Tidal Volume (VT) of the Respiratory Cycle Amount of air moved in or out of lungs during a single respiratory cycle
Inhalation of Respiratory Cycle always active
Exhalation of Respiratory Cycle active or passive
Diaphragm used in inhalation (2) - Contraction draws air into lungs - 75% of normal air movement
External intercostal muscles used in inhalation (2) - Assist inhalation - 25% of normal air movement
Accessory muscles assist in elevating ribs (4) - Sternocleidomastoid - Serratus anterior - Pectoralis minor - Scalene muscles
Internal intercostal and transversus thoracis muscles depress the ribs
Abdominal muscles Compress abdomen and force diaphragm upward
Respiratory movements are classified by (2) - pattern of muscle activity - Quiet breathing (eupnea) - Forced breathing (hyperpnea) - Not breathing (apnea)
Quiet breathing (eupnea) (2) - Diaphragmatic - Costal
The Respiratory Minute Volume (VE) (2) - Amount of air moved in or out per minute - Measures pulmonary ventilation
how to calculate The Respiratory Minute Volume (VE) respiratory rate x tidal volume
Alveolar Ventilation (VA) the amount of air reaching alveoli each minute
At rest Alveolar Ventilation is calculated as Respiratory rate x (tidal volume − anatomic dead space)
Alveoli contain less ... , more ... than atmospheric air O2 and CO2
Respiratory Performance and Volume Relationships Total lung volume is divided into a series of volumes and capacities useful in diagnosing problems
Four Pulmonary Volumes - Resting tidal volume (Vt) - Expiratory reserve volume (ERV) - Residual volume - Inspiratory reserve volume (IRV)
Four Calculated Respiratory Capacities - Inspiratory capacity - Functional residual capacity (FRC) - Vital capacity - Total lung capacity
Inspiratory capacity Tidal volume + inspiratory reserve volume
Functional residual capacity (FRC) Expiratory reserve volume + residual volume
Vital capacity Expiratory reserve volume + tidal volume + inspiratory reserve volume
Total lung capacity Vital capacity + residual volume
Dalton’s Law and Partial Pressures: In a mixture of non-reacting gases, the total ... exerted is equal to the sum of the ... of the individual gases. pressure and partial pressure
Partial pressures are proportional to percentage of the gas in the mixture
Composition of Atmospheric Air (760 mm of Hg) - Nitrogen - Oxygen - Carbond dioxide - nitrogen about 78.6% PN2 = 597 mm of Hg) - Oxygen about 20.9% (PO2 = 159 mm of Hg) - Carbon dioxide about 0.04% (PCO2 = 0.3 mm of Hg)
Created by: JessicaKim1230
 

 



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