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Prevalence & Aetiolo
| Question | Answer |
|---|---|
| Annual statistics cancer | 1 in 2 people will develop cancer. Over 375,000 new cases/year. Survival improving due to early diagnosis & better treatments. |
| How is it diagnosed | How is cancer diagnosed? A: Screening (breast, cervical, bowel), GP referral, imaging (CT/MRI), biopsy to confirm. Early detection improves survival. |
| Survivorship | People living during and after cancer treatment. >3 million in UK. May face fatigue, deconditioning, psychological distress, long-term side effects. |
| Living with cancer | Fatigue, reduced physical function, anxiety/depression, weight changes, fear of recurrence. Exercise & rehab improve quality of life. |
| Most common cancers | Prostate (men), Breast (women), Bowel (both). Risk increases with age; influenced by hormones, lifestyle. |
| Aetilogy | Genetic mutations, hormones, lifestyle (smoking, alcohol, diet, inactivity), infections (viruses like HPV), environmental exposures (UV). |
| Lifestyle risk | Smoking ↑lung, bladder cancer; |
| lifestyle risk | Alcohol ↑breast, liver, bowel; |
| Lifestyle risk | Diet high in processed meat ↑bowel cancer; |
| lifestyle risk | inactivity & obesity various cancers & Sunburn ↑skin cancer. |
| leptin/ obesity and cancer risk P1 | More body fat → more leptin hormone Making cancer cells divide |
| Leptin/ Obesity and cancer risk P2 | Helping blood supply to tumours • Causing inflammation |
| leptin Obesity cancer risk P3 | Boosting oestrogen (for breast/endometrial cancer) • Prevent: healthy weight, exercise, good diet |
| Leptin | A: A hormone from fat cells that controls appetite and can promote cancer growth in obesity. |
| BMI (Body Max Index) | Underweight: <18.5 • Healthy weight: 18.5–24.9 • Overweight: 25–29.9 • Obese (Class 1): 30–34.9 • Obese (Class 2): 35–39.9 |