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CNS Drugs-Seizures
| Question | Answer |
|---|---|
| Epilepsy | a neurological disorder characterized by recurrent, unprovoked seizures caused by abnormal electrical activity in the brain. |
| Absence Seizures | are a type of generalized seizure characterized by brief episodes of staring or loss of awareness, typically lasting only a few seconds. |
| Tonic-Clonic Seizures | also known as grand mal seizures, are a type of generalized seizure that involves two phases: the tonic phase, where the body stiffens and muscles contract, and the clonic phase, characterized by rhythmic shaking or jerking movements. |
| Tonic | stiffening of limbs |
| Clonic | limbs and face begin to jerk |
| Status epilepticus seizures | are continuous tonic-clonic seizures that last longer than five minutes or recur before the end of the postictal period of the previous seizure |
| Partial Seizures | also known as focal seizures, originate in a specific area of the brain and can be classified into two types: simple partial seizures and complex partial seizures. |
| carbamazepine (Tegretol) | First drug of choice for Partial Seizures |
| lamotrigine (Lamictal) | First drug of choice for Tonic-Clonic Seizures |
| ethosuximide (Zarontin) | First drug of choice for Absence Seizures |
| diazepam (Valium) | First drug of choice for Status epilepticus |
| Stevens-Johnson syndrome | is a severe, potentially life-threatening skin condition characterized by widespread skin rash, blistering, and mucous membrane involvement |
| Stomatitis | inflammation of the mucous membranes in the mouth, which can cause symptoms like soreness, swelling, and ulcers |
| Erythema multiforme | a skin condition characterized by the sudden appearance or red, target-like lesions of spots on the skin, often triggered by infections, medications, or other factors |
| Trigeminal neuralgia | a chronic pain condition characterized by sudden, severe facial pain along the distribution of the trigeminal nerve |
| Antiseizure Agents | gabapentin (Neurontin) lamotrigine (Lamictal) levetiracetam (Keppra, Keppra XR) phenytoin (Dilantin) pregabalin (Lyrica) valproate (Depacon, Depakote) carbamazepine (Tegretol) |
| Barbiturate / Antiseizure agent | phenobarbital (Sezaby) (Luminal) |
| gabapentin Neurontin | antiseizure agent |
| lamotrigine Lamictal | Antiseizure agent |
| levetiracetam Keppra, Keppra XR | antiseizure agent |
| phenytoin Dilantin | antiseizure agent |
| pregabalin Lyrica | antiseizure agent |
| valproate sodium Depacon, Depakote | antiseizure agent |
| phenobarbital Sezaby, Luminal | Barbiturate / Antiseizure agent |
| carbamazepine Tegretol | antiseizure agent |