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Infectious Disease 3
| CATEGORY | GENERIC NAME | BRAND NAME | INDICATORS | ACTIVITY | SIDE EFFECTS | US BOXED WARNINGS |
|---|---|---|---|---|---|---|
| Lincosamide Antibiotic | Clindamycin (PO, IV) | Cleocin | SSTI, pharyngitis | MRSA/MSSA, streptococcus species, anaerobes | Diarrhea, clostridioides difficile diarrhea | Clostridioides difficile-associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including clindamycin, and may range in severity from mild diarrhea to fatal colitis |
| Sulfonamide Antibiotic | Sulfamethoxazole and Trimethoprim (PO,IV) | Bactrim, Bactrim DS | SSTI, cystitis, pyelonephritis, opportunistic infection prophylaxis | MRSA, Enterobacteriaceae | Nausea, vomiting, diarrhea, skin rashes (rarely SJS or TEN), photosensitivity, crystalluria, hyperkalemia, increased serum creatinine, hypersensitivity reactions | |
| Urinary Antibiotic | Nitrofurantoin (PO) | Macrobid | Cystitis | Escherichia coli | Nausea, pulmonary fibrosis (chronic use) | |
| Urinary Antibiotic | Fosfomycin (PO) | Monurol | Cystitis | Escherichia coli | Headache, diarrhea, nausea | |
| Aminoglycoside Antibiotic | Tobramycin (IV, inhaled) | Tobi (inhaled) | HAP, cystic fibrosis (nebulized only) | Escherichia coli, Pseudo aeruginosa | Nephrotoxicity, ototoxicity | |
| Glycopeptide Antibiotic | Vancomycin (IV, PO) | Vancocin | IV: SSTI, HAP, meningitis, endocarditis, CRBSI PO: CDI | MRSA, clostridioides difficile (PO only) | Nephrotoxicity, vancomycin infusion reaction, ototoxicity | |
| Antibiotic | Metronidazole (PO, IV) | Flagyl | Anaerobic infections, CDI | Bacteroides species, Clostridioides difficile | Nausea, metallic taste, disulfiram reaction with alcohol, peripheral neuropathy (long-term use) | |
| Antibiotic | Mupirocin (topical) | Bactroban | MRSA decolonization | --- | No major side effects | |
| Topical Antiobiotic | Neomycin + Polymyxin B + Bacitracin (topical, ophtalmic) | Top: Neosporin (OTC) Oph: Neo-Polycin | Topical infection prevention Ocular infections | --- | Reddening, itching |