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Mammography

breast anatomy

QuestionAnswer
The breast is a well-differentiated ____ _____ gland of the same type found in the axilla, groin and elsewhere in the body. modified apocrine
- Also called mammary glands - A specialized version of the typical apocrine sweat glands, which have adapted to perform specific functions in various parts of the body Modified Apocrine glands
MODIFIED APOCRINE GLANDS - Consist of apocrine and eccrine gland - Apocrine: basis of the mammary gland, open into the_____ ____, which then open at the nipple - ________: opens directly to the skin lactiferous ducts : Eccrine
WHAT GLAND - Located in the ear canal - Produces earwax (cerumen), which helps trap dust and foreign particles and protects the eardrum Ceruminous gland
WHAT GLAND - Located in the eyelid, near the eyelashes - Produces sweat-like secretions that help lubricate and protect the eyelid margin Ciliary gland (glands of Moll)
WHAT GLAND - Located in the breast - Undergoes significant growth and functional changes during pregnancy and lactation Mammary gland
Radiographic exam that uses a specialized equipment that uses high contrast resolution Mammography
MALE OR FEMALE? - More prominent and developed mammary gland - Larger size due to greater glandular and fatty tissue Female breast
MALE OR FEMALE? - Poorly developed mammary glands - Contains mostly connective tissue - Smaller size Male breast
MALE OR FEMALE? - Mainly influenced by estrogen and progesterone, which stimulate breast development and changes Female breast
MALE OR FEMALE? - Mainly influenced by testosterone, which limits mammary gland development Male breast
MALE OR FEMALE? - Capable of lactation or breastfeeding after pregnancy Female breast
MALE OR FEMALE? - Do not play a role in lactation Male breast
MALE OR FEMALE? - Nipple and areola are larger and may appear darker, especially during puberty, pregnancy, and lactation Female breast
MALE OR FEMALE? - Smaller and less prominent nipple and areola Male breast
BREAST UNDERGOES DEVELOPMENTAL CHANGES which occurs over several stages influenced by ____ and life stages such as _____, ______, and _____. hormones : puberty : pregnancy : aging
FETAL STAGE (EMBRYONIC DEVELOPMENT) - Around ______ week of gestation, a thickening called _______ _____ or milk line forms in the fetus, which extends from the armpit to groin on each side of the body 4th -6th : mammary ridge
FETAL STAGE (BUD FORMATION) - By the _______ week, the mammary ridge begins to develop into _________ _____ in both male and female fetuses 7th-8th : mammary buds
PUBERTY STAGE - Described using the Tanner stages, named after pediatrician ______ _________, which outline the physical stages of sexual development James Tanner
WHAT TANNER STAGE - No visible breast tissue - Usually seen in 6–9-year-old children - The areola is flat against the chest Pre-pubertal stage
WHAT TANNER STAGE - The first signs of breast development appear as small lumps (breast buds) from under the nipples Breast bud stage
WHAT TANNER STAGE - Commonly occurs between 8–13 years old - Average onset is around 9–10 years old - Often accompanied by the appearance of pubic hair Breast bud stage
WHAT TANNER STAGE - The breast and areola continue to grow, but there is no clear distinction between the two yet - Typical age: 10–14 years Breast elevation
WHAT TANNER STAGE - Average: 11–12 years - Pubic hair becomes darker and spreads, continuing its development Breast elevation
WHAT TANNER STAGE - The areola and nipple form a secondary mound, projecting from the contour of the breast Nipple and areola mound
WHAT TANNER STAGE - Typical age: around 12–14 years, but can vary - The areola becomes more elevated or protruding Nipple and areola mound
WHAT TANNER STAGE - The areola usually returns to the level of the breast contour, with the nipple projecting outward Mature Stage or Adult Contour
TANNER STAGE - Onset usually begins around _________ years old - Male breast bud corresponds to Tanner Stage ___, similar to females - Testosterone suppresses further breast development, so growth usually stops around _______ years old 11–12 : II 15–17
CYCLIC CHANGES - ______ and _________ lead to swelling, tenderness and sometimes lumpiness as the glands prepare for a potential pregnancy - Changes occur cyclically due to _____ fluctuations Estrogen, progesterone : hormonal
PREGNANCY (RAPID GROWTH) - Breasts enlarge significantly due to ______ estrogen and progesterone levels. - Milk-producing glands (______) expand in preparation for lactation increased : alveoli
LACTATION (MILK PRODUCTION) - Following childbirth, the hormone ______ (lactotropin) stimulates milk production. ______ triggers the “let- down” reflex, allowing milk flow from lobules through the ducts. prolactin : Oxytocin
LACTATION (MILK PRODUCTION) - Oxytocin: Triggers let-down reflex by causing ______ cells to contract, allowing milk to flow from lobules through the ducts myoepithelial
LACTATION (COLOSTRUM PRODUCTION) - Initially, the breasts produce colostrum, a nutrient-rich yellowish fluid that provides essential _____ and ______ to the newborn antibodies, nutrients
The stage in a woman’s life when menstrual cycles permanently stop. Menopause
The period after menstruation has permanently stopped. Post-menopause
The period after menstruation has permanently stopped. Glandular tissue
The breast tissue that shrinks during menopause due to decreased estrogen levels. Fat tissue
Shrinkage of glandular tissue due to less estrogen: - Reduction in Size and Density - Increased Fat Tissue (as glandular tissue is gradually replaced by fat) - Sagging and Changes in Shape
MENOPAUSE/POST-MENOPAUSE - Breasts become ____ and ____ _____ because fat replaces most of the glandular tissue softer, less firm
QUADRANTS OF THE BREAST Upper Outer quadrant Upper Inner quadrant Lower Outer quadrant Lower Inner quadrant
CLOCK/FACE TIME REFERENCES OF THE BREAST 12 o'clock 3 o'clock 6 o'clock 9 o'clock
Specific guide points on the body used in medical practice - Examples? External landmark: Nipple, axilla, inframammary fold
Visible or palpable structures on the surface of the breast - Examples? External anatomy : Skin, nipple, and areola
EXTERNAL ANATOMY - _____: Adjacent/near the chest wall - _____: Adjacent/near the nipple Base Apex
Refers to the border of normal tissue around a tumor that is removed during surgery Breast margins
WHAT BREAST MARGIN - No cancer cells at the outer edge Negative (Clear) Margins
WHAT BREAST MARGIN - Cancer cells are present at the outer edge - Needs more surgery Positive Margins
WHAT BREAST MARGIN - The cancer cells are near but not at the ridge - May or may not call for surgery Close Margins
______ of the breast refer to anatomical directions and boundaries used when describing the location of the breast tissue or tumors within the breast Margins
- Refers to the upper part of the breast? - Refers to the lower part of the breast? Superior : Inferior
- Refers to the armpit or underarm area? - Refers to the inner or middle part of the breast closest to the sternum? Axillary : Medial
- Smooth circular darkened area surrounding the nipple? - Small glands found on the areola that enlarge during pregnancy? Areola : Montgomery’s glands (Morgagni’s tubercles)
It is a raised, darkened circular extensions with multiple crevices or narrow opening Nipple
NIPPLE - Within the nipple's crevices are ____ orifices (collecting ducts) that transfers milk from the lactiferous ducts 5-7
The skin covering of the breast is thickest at the ____ of the breast (about ______ thick) and becomes thinner as it approaches the _____ (0.5mm) base : 2mm : nipple
Triangular shaped projection where the breast tissue extends into the lower axilla - Common site of breast cancer Tail of Spence/Axillary tail of Spence
- Also known as the inframammary crease or line - It is a natural fold or crease where the bottom of the breast meets the chest wall Inframammary fold
- Important in breast surgery to achieve symmetry and aesthetic results - Serves as a surgical guide for incisions and implant placement Inframammary fold
WHAT FASCIAL LAYERS - consists of fat and fibrous tissue which helps give the breast its shape and mobility Superficial Fascia or Camper’s Fascia
WHAT FASCIAL LAYERS - layer of dense connective tissue that plays a crucial role in supporting and anchoring the breast to the chest wall Deep Fascia or Pectoral Fascia
WHAT FASCIAL LAYERS - Strong and firm - Relatively fixed to underlying structures, providing stability to the breast Deep Fascia or Pectoral Fascia
The supportive structure of the breast that extends outward attaching to the anterior superficial fascia of the skin Cooper's ligament
- Surround the breast and support glandular tissue - Help maintain the shape and contour of the breast Cooper's ligament
The pendulous presentation when the breast is stretched - Causes: ________ of ligaments (commonly after pregnancy, weight gain, or weight loss) and _________ of supportive tissue Cooper's droop : Stretching, weakening
NOTE - Not all breast sagging is Cooper’s droop - ________ can also occur due to tissue changes, especially from decreased ______ Sagging : estrogen
It is a space formed by a layer of adipose tissue and connective fascia that separates the breast from the pectoralis muscle Retromammary fat space
- Acts as a slippery layer, allowing the breast to slide smoothly over the chest wall - Provides cushioning and mobility Retromammary fat space
Internally, the breast includes a varying mixture of fatty tissue and parenchyma - Components? - Glandular Components - Lymphatic Networks - Blood Vessels - Connective and Supportive Stroma
GLANDULAR PARENCHYMA (GLANDULAR TISSUE) - It consists of ______ lobes that extends from the nipple in a _____ pattern where the ductal flow will follow 15-20 : radial
LOBES AND DUCTAL STRUCTURES - Each 15–20 lobes contains a _____ pattern of ductal structures - There are ___ layers of epithelial cells that lines the lumen of the ducts - Beneath the epithelial layer is a layer of _____________ treelike : 2 : myoepithelium
LOBES AND DUCTAL STRUCTURES - Extending from the nipple orifice, the duct starts as a ______ _____ that immediately widens into the___________ _____ (ampulla), it is a pouch-like structure that again narrows as it joins one or more segmental duct collecting duct : lactiferous sinus :
- It is the minute (1 to 2 mm) portion of the duct the holds the milk-producing elements of the breast - A single lobe contains many of these Lobules
-It is a small duct just outside and leading to the lobule? - It is a small duct inside the lobule? Extralobular Terminal Duct : Intralobular Terminal Duct
- Located at the end of the intralobular duct - It is a blind ending to the ductal pattern corresponding to acinus Terminal Ductules
- These are sac-like, milk producing unit of the breast - The functional units of the breast where milk is produced. Acini
ACINI - The cells within the ____ secrete milk into small ducts, which then carry it through the ______ _____ and larger milk ducts to the nipple - ___ and _____ stimulate growth of acini - ___ stimulates milk production acini : terminal ductules : Estrogen, progesterone : Prolactin
- is the critical hub of the functioning breast and is responsible for milk production and hormonal and nutritional exchange. Terminal Duct Lobular Unit
- Starts from extralobular terminal duct → acini - Most of the pathology arise from TDLU Terminal Duct Lobular Unit
___ → Lobules → Terminal ductules → Intralobular duct → Extralobular duct → Segmental duct → _____ ____ → Lactiferous duct → Nipple Acini : Lactiferous sinus
The TDLU is composed of: - ___ ___ __: The small duct just outside the lobule that leads into it. - ___ ___ ___: The duct inside lobule. - ___ ___: Smaller ducts that branch from intralobular duct. - ____: Milk-producing sacs at ends of the ductules. Extralobular terminal duct : Intralobular terminal duct : Terminal ductules : Acinus (Acini)
Created by: yulyae
 

 



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