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chapter 14
| Term | Definition |
|---|---|
| Epilepsy: | is a neurological disorder characterized by recurrent, unprovoked seizures caused by abnormal electrical activity in the brain. |
| Absence Seizures: | are a type of generalized seizure characterized by brief episodes of staring or loss of awareness, typically lasting only a few seconds. |
| Tonic-Clonic Seizures: | also known as grand mal seizures, are a type of generalized seizure that involves two phases: the tonic phase, where the body stiffens and muscles contract, and the clonic phase, characterized by rhythmic shaking or jerking movements. |
| Tonic: | stiffening of limbs |
| Clonic: | limbs and face begin to jerk |
| Status epilepticus seizures: | are continuous tonic-clonic seizures that last longer than five minutes or recur before the end of the postictal period of the previous seizure |
| Partial Seizures: | also known as focal seizures, originate in a specific area of the brain and can be classified into two types: simple partial seizures and complex partial seizures. |
| carbamazepine (Tegretol) – | First drug of choice for Partial Seizures |
| lamotrigine (Lamictal) – | First drug of choice for Tonic-Clonic Seizures |
| ethosuximide (Zarontin) – | First drug of choice for Absence Seizures |
| diazepam (Valium) – | First drug of choice for Status epilepticus |
| Stevens-Johnson syndrome: | is a severe, potentially life-threatening skin condition characterized by widespread skin rash, blistering, and mucous membran involvement. |
| Stomatitis: | inflammation of the mucous membranes in the mouth, which can cause symptoms like soreness, swelling, and ulcers. |
| Erythema multiforme – | a skin condition characterized by the sudden appearance or red, target-like lesions of spots on the skin, often triggered by infections, medications, or other factors |
| Trigeminal neuralgia – | a chronic pain condition characterized by sudden, severe facial pain along the distribution of the trigeminal nerve. |
| Antiseizure Agents | gabapentin (Neurontin), lamotrigine (Lamictal), levetiracetam (Keppra, Keppra XR), phenytoin (Dilantin), pregabalin (Lyrica), valproate (Depacon, Depakote), carbamazepine (Tegretol) |
| Barbiturate / Antiseizure agent | phenobarbital (Sezaby) (Luminal) |