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ID 4

BrandGenericPharmacologic CategoryIndicationEssential Knowledge
Lamisil terbinafine (PO. topical (OTC)) Allylamine antifungal Onychomycosis Key Side Effects: nausea, abdominal pain, diarrhea, elevated hepatic transaminases, headache
Diflucan fluconazole (PO, IV) Azole antifungal Vulvovaginal candidiasis, oropharyngeal candidiasis, invasive candidiasis Key Side Effects: nausea, abdominal pain, diarrhea, QTc prolongation, elevated hepatic transaminases
Nizoral ketoconazole (PO, topical) Azole antifungal Tinea infections nausea, abd pain, diarrhea, QTc prolongation, increased hepatic transaminases BW: serious hepatotoxicity, including cases w/ a fatal outcome/ requiring liver transplantation; may cause QTc prolongation and drug interactions leading to QTc prolongation
-- nystatin (PO) Polyene antifungal Oropharyngeal candidiasis Key Side Effects: phlebitis, diarrhea, vomiting, anemia, fever
Nystop nystatin (topical) Polyene antifungal Cutaneous and mucocutaneous fungal infections Key Side Effects: burning, itching Other Notes: only use oral solutions for thrush
Mycamine micafungin (IV) Echinocandin antifungal invasive candidiases Key Side Effects: no major side effects
Lotrisone betamethasone and clotrimazole (topical) Glucocorticoid and azole antifungal Cutaneous fungal infections Key Side Effects: burning, itching, dryness, skin atrophy Other Notes: do not use for diaper dermatitis; adrenal suppression with long-term use over large areas of skin
Tamiflu oseltamivir (PO) neuraminidase inhibitor antiviral influenza Key Side Effects: nausea, vomiting, neuropsychiatric events (i.e.,c onfusion, delirium, hallucinations) in pediatric patients (rare)
Zovirax acyclovir (PO, IV) antiviral herpes simplex virus Key Side Effects: nausea, increased hepatic transaminases, crystalluria Other Notes: vesicant
Valtrex valacyclovir (PO) antiviral herpes simplex virus Key Side Effects: nausea, increased hepatic transaminases
Paxlovid nirmatrelvir + ritonavir (PO) antiviral COVID-19 Key Side Effects: diarrhea, dysgeusia US Boxed Warning: significant drug interactions; strong CYP3A inhibitor
Veklury remdesivir (IV) antiviral COVID-19 Key Side Effects: hyperglycemia, renal impairment, bradycardia, increased liver enzymes, hypersensitivity
Truvada emtricitabine + tenofovir disoproxil fumarate (PO) nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) HIV infection, PreP (pre-exposure prophylaxis), PEP (post-exposure prophylaxis) Key Side Effects: decreased bone mineral density, kidney injury, nausea, diarrhea US Boxed Warnings: post treatment acute exacerbation of hepatitis B, risk of drug resistance with use for preexposure prophylaxis
Biktarvy emtricitabine (NRTI) + tenofovir alafenamide (NRTI) + bictegravir (INSTI) nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) and Integrase strand transfer inhibitor (INSTI) HIV infection SE: increased serum bilirubin, headache, weight gain, insomnia, diarrhea, nausea BW: post treatment acute exacerbation of hepatitis B Other Notes: take oral INSTIs 2 hours before or 6 hours after products containing Ca, Al, Mg, or Fe
Created by: Kaitlynyip
 

 



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