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Study guide
| Term | Definition |
|---|---|
| Correct order for lymphocyte circulation | bone marrow & thymus, venous blood, arterial blood, lymphoid tissue, peripheral tissue, capillary network, lymph vessel, lymph node |
| What are 3 examples of antigens | Bacteria, viruses, fungi |
| What are the types of acquired immunity | Humoral and Cellular |
| How do antigens initiate the immune response | They act as foreign markers that bind to specific receptors on B and T lymphocytes |
| What is the major role of macrophages | Engulfs and digest foreign particles and do antigen presentation |
| What does a plasma cell do | Produces lots of immunoglobulin and cranks out antibodies to identify antigens |
| What is immunoglobulin and what does it do | A Y shaped glycoprotein produced by plasma cells that recognizes foreign substances, activates complement, and binds to and neutralizes antigens like bacteria and viruses |
| What is complement | Group of blood born proteins activated after binding to antibody covered antigens. When activated, causes lysis of the microorganisms and enhances inflammatory response |
| Lymphokines | Chemicals released by sensitized T cells |
| Monokines | Chemicals released by activated macrophages |
| Allergic reaction | Peanut proteins enter body and bind to IgE antibodies on mast cells. Mast cells release Histamine, causing allergic reactions to the skin, nose, lungs, Digestive System, and blood vessels. Could go into anaphylactic shock |
| Anaphylactic Shock | Systemic (Body wide) acute allergic response |
| Congenital immunodeficiency illness | SCID. The person is born with the condition- caused by genetic defects. Symptoms appear in infancy or early childhood |
| Acquired immunodeficiency illness | AIDS. The condition develops later in life. Immune system was normal at birth but was weakened form infections, diseases, malnutrition, medical treatments, etc. |
| Examples of autoimmune diseases | Grave's disease, rheumatoid arthritis, multiple sclerosis |
| What goes wrong in autoimmune diseases | The immune system doesn't tolerate self antigens, but still recognizes and attacks foreigns. So the body produces antibodies and sensitized T cells that attack and damage its own tissues |
| Where are the three main lymph nodes | Axillary, Cervical, Inguinal |
| What are the three main points about the specific body defenses | It's systemic, it's antigen specific, it has memory |
| Primary Organs | where lymphocytes are made and trained |
| Secondary organs | where trained lymphocytes gather and respond to infection |