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Infectious Disease 4
| Generic Name | Brand Name | Pharmacological Category | Common Indications | Classification | Key Side Effects |
|---|---|---|---|---|---|
| Terbinafine (PO, topical) | Lamisil | Allylamine antifungal | Onychomycosis | Topical: OTC | Key Side Effects: nausea, abdominal pain, diarrhea, elevated hepatic transaminases, headache |
| Fluconazole (PO,IV) | Diflucan | Azole antifungal | Vulvovaginal candidiasis, oropharyngeal candidiasis, invasive candidiasis | Key Side Effects: nausea, abdominal pain, diarrhea, QTc prolongation, elevated hepatic transaminases | |
| Ketoconazole (PO, topical) | Nizoral | Azole antifungal | Tinea infections | Topical: OTC | Key Side Effects: nausea, abdominal pain, diarrhea, QTc prolongation, increased hepatic transaminases |
| Nystatin (PO) | --- | Polyene antifungal | Oropharyngeal candidiasis | Key Side Effects: phlebitis, diarrhea, vomiting, anemia, fever | |
| Nystatin (topical) | Nystop | Polyene antifungal | Cutaneous and mucocutaneous fungal infections | Key Side Effects: burning, itching | |
| Micafungin (IV) | Mycamine | Echinocandin antifungal | Invasive candidiasis | Key Side Effects: no major side effects | |
| Betamethasone and clotrimazole (topical) | Lotrisome | Glucocorticoid and azole antifungal | Cutaneous fungal infections | Key Side Effects: burning, itching, dryness, skin atrophy | |
| Oseltamivir (PO) | Tamiflu | Neuraminidase inhibitor antiviral | Influenza | Key Side Effects: nausea, vomiting, neuropsychiatric events (i.e., confusion, delirium, hallucinations) in pediatric patients (rare) | |
| Acyclovir (PO, IV) | Zovirax | Antiviral | Herpes simplex virus | Key Side Effects: nausea, increased hepatic transaminases, crystalluria | |
| Valacyclovir (PO) | Valtrex | Antiviral | Herpes simplex virus | Key Side Effects: nausea, increased hepatic transaminases | |
| Nirmatrelvir + ritonavir (PO) | Paxlovid | Antiviral | COVID-19 | Key Side Effects: diarrhea, dysgeusia | |
| Remdesivir (IV) | Veklury | Antiviral | COVID-19 | Key Side Effects: hyperglycemia, renal impairment | |
| Emtricitabine + Tenofovir disoproxil fumarate (PO) | Truvada | Nucleoside/Nucleotide reverse transcriptase inhibitor (NRTI) | HIV infection, PreP, PEP | Key Side Effects: decreased bone mineral density, kidney injury, nausea, diarrhea | |
| Emtricibine (NRTI) + Tenofovir alefenamide (NRTI) + bictegavir (INSTI) (PO) | Biktarvy | Nucleoside/Nucleotide reverse transcriptase inhibitor (NRTI) and integrase strand transfer inhibitor (INSTI) (PO) | HIV infection | Key Side Effects: increased serum bilirubin, headache, weight gain, insomnia, diarrhea, nausea |