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Cardiovascular 4
CV 4
| Generic | Brand | Pharmacologic Category | Common Indication | Essential Knowledge |
|---|---|---|---|---|
| amiodarone (PO, IV) | Pacerone, Nexterone | Antiarrhythmic | AF (rhythm control), ventricular fibrillation, ventricular tachycardia | Key Side Effects: hyperthyroidism, pulmonary toxicity, hepatotoxicity, epithelial keratopathy, US Warnings: intended only for life-threatening arrhythmias; pulmonary toxicity, hepatotoxicity; proarrhythmic Other Notes: many drug interactions |
| ezetimibe (PO) | Zetia | Cholesterol absorption inhibitor | Dislipidemia | Key Side Effects: myalgias, diarrhea |
| fenofibrate (PO) | Tricor, Trilipix | Fibric acid derivative | Hypertriglyceridema | Key Side Effects: dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases |
| gemfibrozil (PO) | Lopid | Fibric acid derivative | Hypertriglyceridema | Key Side Effects: dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases |
| atorvastatin (PO) | Lipitor | HMG-CoA reductive inhibitor | Dyslipidemia, CAD, stoke | Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
| lovastatin (PO) | Altoprev | HMG-CoA reductive inhibitor | Dyslipidemia, CAD, stoke | Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
| pravastatin (PO) | Pravachol | HMG-CoA reductive inhibitor | Dyslipidemia, CAD, stoke | Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
| rosuvastatin (PO) | Crestor | HMG-CoA reductive inhibitor | Dyslipidemia, CAD, stoke | Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
| simvastatin (PO) | Zocor | HMG-CoA reductive inhibitor | Dyslipidemia, CAD, stoke | Key Side Effects: myopathy/rhabdomyolysis Other Notes: avoid excessive grapefruit juice intake, avoid in pregnancy and breastfeeding |
| omega-3 ethyl esters (PO) | Lovaza (OTC available; Rx:Lovaza & Vascepa) | Omega-3-fatty acid | Hypertriglyceridema | Key Side Effects: dyspepsia, eructation, fishy aftertaste Other Notes: can prolong bleeding time when used with other medication that can increase bleeding risk, use caution with fish/shellfish allergy |
| icosapent ethyl (PO) | Vascepa (OTC available; Rx:Lovaza & Vascepa) | Omega-3 fatty acid | Hypertriglyceridema | Key Side Effects: eructation, arthralgia Other Notes: can prolong bleeding time when used with other medication that can increase bleeding risk, use caution with fish/shellfish allergy |