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Acquired immunity

TermDefinition
T cells cell mediated immunity
B cells humoral immunity antibody response
antigen generated antibody if foreign
epitope specific portion of antigen that stimulates immune response
antibody produced by B-cells, tag antigens
antigen presenting cells presents antigen to B+T cells phagocytize pathogen digest pathogen to sep. epitope display epitope on cell surface to present to adaptive immune system
T cell function respond to pathogen inside cells made in bone marrow mature in thymus
Activated T cells cytotoxic T cells Helper T cells Memory T cells
cytotoxic t cells secrete chemicals to kill infected cells
helper T cells assist other cells (activate B cells)
memory T cells reserved for future infection events with same pathogen
Immunocompetence body can properly activate lymphocytes in response to foreign antigen
Major histocompatibility complex (MHC) display antigen on cell surface
MHC1 self & non self; all nucleated cells
MHC2 nonself antigen (macrophages, dendrites, B-cells, APC's
B cell functions humoral/ antibody immunity respond to pathogens in blood antibody!! made in bone marrow matures in bone marrow
B cells when activated by helper T cells become plasma cells & memory B cells
plasma cells secrete antibody
memory B cells reserved for future infection events
pyrogens 2nd line of defense signals fever via hypothalamus increase immune function kill pathogens that are temp. sensitive
antibodies protein (globulin) made by plasma B cells have antigen binding sites dont directly kill antigens or pathogens
agglutination formation of "clump" bc the binding of multiple antigens @ once
neutralization antibodies occupy binding sites & prevents other actions
opsonization tag antigens, makes an easier target for phagocytes
complement fixation participate w completement proteins for cell lysis
Created by: huntybaby
 

 



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