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Humans and Microbes
Interactions between Humans and Microbes
| Term | Definition |
|---|---|
| Microbial antagonism | Competition between microbes |
| Symbiosis | Relationship between two organisms where at least one is dependent on the other |
| Infection | Microbes get past host defenses, enter tissues, and multiply |
| Disease | Deviation from health that results when cumulative effects of infection damage or disrupt tissues and organs |
| Infectious disease | Disease that causes harm to organism |
| Pathogenicity | An organism's potential to cause disease |
| True Pathogens | Dangerous at all times (ex. flu) |
| Opportunistic Pathogens | Cause disease when host defenses are compromised |
| Virulence | Severity of a disease by a particular microbe (degree of pathogenicity) |
| Virulence Factor | Characteristics and structure of microbe that contributes to the ability of it to damage organism |
| Exogenous | Enters from outside the body |
| Endogenous | Begins from somewhere in the same host |
| Infectious Dose (ID) | Minimum number of microbes needed to cause an infection |
| Adhesion | Microbe attachment to host tissues |
| Phagocytes | Immune cells that engulf and destroy pathogens |
| Leukocidins | Kill phagocytes |
| Capsules and slime layers | Difficult for the phagocyte to engulf pathogen |
| Toxin | A specific chemical product of microbes that is poisonous to other organisms |
| Exotoxins | Secreted proteins that are deadly in small amounts |
| Endotoxins | LPS from gram-negative cells |
| Local Infection | Pathogens are limited to a small area of the body |
| Systemic Infection | An infection throughout body |
| Focal Infection | Begins as localized infection and turns into systematic infection |
| Primary Infection | Acute infection that causes illness |
| Secondary Infection | Infection that occurs after a primary infection from weakened body defenses |
| Acute disease | Symptoms develop rapidly but don't last long |
| Chronic disease | Symptoms develop slowly |
| Symptoms | Changes in body function that are felt by patient (pain, fatigue) |
| Signs | Changes in body that are observable (fever, vomiting) |
| Syndrome | A specific group of signs and symptoms that accompany a disease |
| Latency | Dormant microbial state |
| Sequelae | Long-term or permanent damage to tissues or organs caused by infectious disease |
| Incubation Period | Time from initial contact with pathogen to appearance of symptoms |
| Prodromal stage | 1-2 day period when the earliest symptoms appear |
| Acute phase | Microbe multiplies at high levels and becomes well established in host |
| Convalescent period | Patient responded to infection and health returns |
| Reservoir | Primary habitat in the world from which a pathogen originates |
| Transmitter | Individual or object from which an infection is acquired |
| Carrier | An individual with a dormant pathogen that spread it to others |
| Zoonosis | An infection of animals but transmissible to humans |
| Communicable Disease | Disease that can spread between hosts |
| Contagious Disease | Disease that are easily and rapidly spread between host |
| Noncommunicable Disease | Disease that is not spread between hosts |
| Horizontal Transmission | Disease spread through population from one infected individual to another |
| Direct contact | Close contact between people |
| Indirect Transmission | Object or substance carries agent between hosts |
| Vector Transmission | Arthropods (organism) that harbors and transfers infection |
| Vertical Transmission | Spread between generations |