Infed, Venofer (ferrous sucrose)

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Hospital IPPE Exam 2

Generic	Brand	Drug Class	Indication	BBW 1	BBW 2	High alert	Dose
Metoclopramide	Reglan	Dopamine-2 receptor antagonist	Nausea/vomiting, gastroparesis	Tardive dyskinesia			IV: 10 mg IV over 1 - 2 min.
Famotidine	Pepcid	Histamine 2 receptor antagonist	Duodenal ulcer	CNS (confusion, delirium, hallucinations, disorientation) in elderly			20 mg BID or 40 mg daily
Lactulose	Enulose, Generlac	Laxative - Osmotic	Prevention and treatment of hepatic encephalopathy (complication of liver disease, cirrhosis)	Avoid in galactosemia			15 - 30 mL (10 - 20 g) orally once daily, increased to 60 mL (40 g) once daily
Pantoprazole	Protonix	Proton pump inhibitor	Heartburn, Gastroesophageal reflux disease (GERD), Peptic ulcer disease	C. diff infections, bone fractures, vitamin B12 deficiency with prolonged use			40 mg IV/PO daily
Ondansetron	Zofran	Serotonin 5-HT3 receptor antagonist	Nausea, vomiting	Markedly prolonged QT interval leading to torsades de pointes	Hypersensitivity to 5-HT 3 receptor antagonist or any component of the formulation		IV: 0.15mg/kg x 3 doses, max: 16 mg PO: 8 - 16 mg
Epoetin alfa	Epogen, Procrit	Erythropoiesis stimulating agent	Anemia secondary to chronic kidney disease	Serious and life-threatening side effects and/or death when raising hemoglobin target of 12 g/dL or higher			Various
Iron dextran	Infed, Venofer (ferrous sucrose)	Essential mineral	Anemia, dietary supplement
Methotrexate	Trexall, Rheumatrex	Antimetabolite	Rheumatoid arthritis, Crohn's disease, ulcerative colitis, cancer				10-20mg PO/SC Weekly
Dexamethasone	Decadron	Corticosteroid	Inflammation	Infections			0.75-9 mg/day in divided doses Q6-12H
Hydrocortisone	Solu-Cortef	Corticosteroid	Inflammantion, rash	Infections			IV: 15-240 mg Q12H
Methylprednisolone	Solu-Medrol	Corticosteroid	Inflammation	Fungal Infections	Live vaccination		4 - 48 mg per day (anti-inflammatory); 4 mg methylprednisolone = 5 mg prednisone
Adalimumab	Humira	Tumor necrosis factor (TNF) blocker	Rheumatoid arthritis, psoriasis, Crohn's disease, ulcerative colitis	Serious infections	Cancer		RA: 40 mg injected every 1 to 2 weeks; Crohn's: titrate with maintenance 40 mg injected every other week
Infliximab	Remicade	Tumor necrosis factor (TNF) blocker	Rheumatoid arthritis, Crohn's disease, ulcerative colitis	Serious infections	Cancer		Varies
Methocarbamol	Robaxin	Muscle relaxant	Musculoskeletal discomfort				IV: 1 g IV daily (or Q8H); Max: 3 g per day
Fosphenytoin	Cerebyx	Anticonvulsant	Epilepsy	Severe hypotension, cardiac arrhythmia with rapid IV administration			Load: 15 to 20 mg of phenytoin sodium equivalents (PE)/kg IV at 100 to 150 mg PE/min. Do not exceed 150 mg/min (phenytoin equivalent); 1.5 mg fosphenytoin = 1 mg phenytoin
Haloperidol	Haldol	Antipsychotic	Schizophrenia	Increased mortality in elderly with dementia-related psychosis			2 - 5 mg IM
Lorazepam	Ativan	Benzodiazepine	Anxiety			***	4 mg IV in 10-15 min; Max: 8 mg
Midazolam	Versed	Benzodiazepine	Sedation			***	0.02 to 0.04 mg/kg; repeat Q5min prn to desired effect or up to 0.1-0.2 mg/kg
Phenytoin sodium	Dilantin	Hydantoin	Epilepsy	Severe hypotension, cardiac arrhythmia with rapid IV administration			Load: 10 to 15 mg/kg by slow IV infusion, not exceeding 50 mg/min; Maintenace: 100 - 300 mg PO daily
Prochlorperazine	Compazine	Phenothiazines	Nausea, vomiting; schizophrenia				Nausea/Vomitting: 5 or 10 mg TID - QID. Psychosis - 5 - 10 mg PO TID - QID (mild); 10 - 20 mg PO TID - QID (moderate - severe)
Propofol	Diprivan	Sedative - Hypnotic	Sedation			***	Induction of anesthesia: 2-2.5 mg/kg; maintenance of anesthesia: 100-200mcg/kg/hr for 10-15 mins)
Sumatriptan	Imitrex	Selective serotonin receptor agonist	Migraine	Ischemic heart disease or uncontrolled hypertension	Pregnancy, peripheral vascular disease, MAO-I inhibitors within 2 weeks		6-12 mg SQ injection
Clindamycin	Cleocin	Antibiotic	Bacterial infection	C. diff infections			IV or IM: 600 - 1200 mg/day divided in 2, 3, or 4 equal doses
Vancomycin	Vancocin	Antibiotic	Bacterial infection	Infusion-related pruritis, erythematous rash			IV: 500 mg every 6 hours or 1000 mg every 12 hrs (PK dosing)
Gentamicin	Garamycin	Antibiotic - Aminoglycoside	Bacterial infection				Serious or life threatening infections and normal renal function: 3 - 5 mg/kg/day divided into 3 to 4 doses; needs renal dosage adjustment
Cefazolin	Ancef	Antibiotic - Cephalosporin	Bacterial infection	Allergy to β-lactams			1-1.5 IV Q6H -Q12H (depending on infection)
Cefepime	Maxipime	Antibiotic - Cephalosporin	Bacterial infection	Allergy to β-lactams			1 - 2 g IV Q12H x 7 - 10 days
Ceftriaxone	Rocephin	Antibiotic - Cephalosporin	Bacterial infection	Allergy to β-lactams			1 - 2 g IV daily or BID; Max: 4g/day
Azithromycin	Zithromax	Antibiotic - Macrolide	Bacterial infection				250 - 500 mg IV or PO daily x 7-10 days
Metronidazole	Flagyl	Antibiotic - Nitroimidazole	Bacterial infection				Load: 15 mg/kg IV; Maintenance: 7.5 mg/kg IV Q6H
Linezolid	Zyvox	Antibiotic - Oxazolidinone	Bacterial infection	Serotonin sydrome when co-administration with SSRI, SNRI, bupropioin, triptans, opioids			600 mg IV/PO Q12H
Ampicillin/sulbactam	Unasyn	Antibiotic - Penicillin + beta-lactamase inhibitor	Bacterial infection				1.5 - 3g IV/IM Q6H (not to exceed 12g/day)
Piperacillin/Tazobactam	Zosyn	Antibiotic - Penicillin + beta-lactamase inhibitor	Bacterial infection	Allergies to PCN			3.375 g every 6 hrs or 4.5 g every 6-8 hrs
Ciprofloxacin	Cipro	Antibiotic - Quinolone	Bacterial infection	Blackbox: tendinitis and tendon rupture	Myasthenia gravis		IV: 200 - 400 mg IV Q8 - 12 H; PO: 250 - 750 mg PO Q12 H x 3 - 14 days
Levofloxacin	Levaquin	Antibiotic - Quinolone	Bacterial infection	Hypersenstivity to levofloxacin, any component of formulation, or other quinolones	Tendinitis and tendon rupture; Myasthenia gravis		250 to 750 mg IV/PO daily (duration depends on infection)
Trimethoprim/Sufamethoxazole	Bactrim	Antibiotic - Sulfonamide + folic acid inhibitor	Bacterial infection				UTI: 8-10 mg/kg (divided in 2 to 4 doses); requires renal dose adjustment; not used in ESRD
Amphotericin B	Ambisome, Abelcet	Antifungal	Fungal infection - systemic	Should not exeed daily dose of greater than 1.5 mg/kg (fatal cardiac or cardiopulmonary arrest)			CNS fungal infections: 0.25 to 0.3 mg/kg IV daily with doses increased by 5 to 10 mg/day to reach a full dose of 0.5 to 0.7 mg/kg/dose IV once daily
Fluconazole	Diflucan	Antifungal	Candidiasis	CYP 450 metabolized drugs	QT prolongation		150 mg IV/PO daily; loading dose 200 to 800 mg daily
Ertapenem	Invanz	Carbapenem	Bacterial infection	Seizures (in patients with CNS disorders)			1 g IV daily 3 - 14 days (IM: max 7 days)
Meropenem	Merrem	Carbepenem	Bacterial infection	Co-admin with valproic acid or divalproex increase risk of breakthrough seizures			0.5 - 1 g IV Q8H (not to exceed 2 g IV Q8H)

Created by: cakedo6

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