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drugs afect CNS
pharm
| Question | Answer |
|---|---|
| CNA stimulants | crosses the BBB Based off of age and renal functions |
| drug class | anorexiants |
| exmaples | phentermine HCL benzphetamine methamphetamine |
| side affects | palpitions dry mouth |
| AMPHETAMINES | ADDERAL, ritalin increeases nuerotranmitters in cns txt an dmanages ADHD |
| actions | increases release of norepineephrine and dopamine in cerebral cortex to reticular activation system |
| uses | narcolypsea and ADHD |
| precautions | GLAUCOOMA -IOP- cardiac structural abnormalities |
| side affects | tachycardia and palpitations |
| MUSCLE RELAXANTS examples | baclofen, soma ,metaxolone- skelaxin |
| uses | muscle spasticity, mutiple sclerosis, |
| adverse reactions | dorwziness,hypotension,coonstipatiosn, siezires, renal impaiment, the HOLY TRINITY |
| nursing | Avoid CNS depressants avoid alcholol do not abruptly stop taking medications |
| antiepileptic/ANTICONVULSANTS | Stabilzes storm/ increase sizzer threshhold |
| HYDANTOINS | Stabilize the hyperexitabilty post synaptically in motor cortex of brain |
| uses | tonic clonic seiziers, status epilepticus, prophylatic seizure preventions |
| examples | phenytoin/ dilantinin IV only with normal saline |
| adverse reactions | gingival hyperplasia |
| nursing | DO not gve IM do not stop taking abruprtly monitor LFTS hygin mouth- dentist, risk fals for injury |
| CARBOXLIC ACID DERIVATIVES | the P organs pancretitus,platlets |
| actions | increase levals of GABA |
| uses | controlling generalized and partial seizures |
| exmmaple | vaproic acid |
| adverse reactions | suicidal thoughts hepatoxic ancreatitis |
| nursing | Monitor for sucidial thoughts monitor for liver funtions |
| SUCCINIMIDES | depress the motor cortex |
| ues | partial seizures |
| adverse reactions | gingival hyperplasia blood dyscrasias |
| interactions | barbiturates valproic acid |
| nursing | take as directed, do not dtop abruptly avoid alcohol CNS depressents m/o resp status |
| Benzodiazepines | pam and lam driving a benz |
| actions | elevate the siezure threshold |
| uses | siezure disorders panic disorders aclholo withdrawls |
| example | clonazepa diazipam lorazepam xanax |
| adverse reactions | apnea, cardiac arrest |
| nursing | do not mix with seditives other CNS depressents alcholol use cautin in elderly m/o vitals |
| lorazapam antidote | flumazenil -romazicon- |
| miscellanous needs | lamotrigine-lamicatal-,levetiracetam--keppra carbamazepine -tegrol- pregabalin-lyrica toprimate- topomax |
| uses | parital seizures epiepsy migranze(keppra and topomax) |
| nursing | avoid CNS depressents m/o vs oeriphreal nueropthy in diabaites |