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medsurg exam 2

thyroid cancer/surgery and adrenal conditions

QuestionAnswer
5 year relative survival of thyroid cancer 2013-2019 98.5%
thyroid cancer background Differentiated: highly treatable and usually curable Poorly differentiated: metastasize, poor prognosis
risk of thyroid cancer Affects women > men Most common 25 - 65 years Incidence increasing over the last decade
how is thyroid cancer first detected Most commonly presents as a cold nodule
thyroid cancer presents as a cold nodule on the scan
staging of thyroid cancer TNM approach tumor, nodes, metastasized?
surgery for thyroid cancer Both lobes if tumor at least 1.0-2.0 cm in diameter, extrathyroid extension or metastases Unilateral lobectomy and isthmusectomy if tumor unifocal and less then 1.0cm
thyroid surgery post op care Observe for respiratory distress Pain control (pain meds) Fluid balance Advise limit talking initially Encourage out of bed as soon as possible
during thyroid surgery post op care, to prevent respiratory distress, you should have an emergency trach tray set up just in case
when a pt is recovering from thyroid surgery, support their neck in high fowlers
treatment after total thyroidectomy surgery Radioactive iodine (I-131)
Radioactive iodine (I-131) works by destroying tissue + metastasis anything that's left
in addition to radioactive iodine, after a total thyroidectomy, the pt should remain left away from the general public and family for 24hrs
other treatments for thyroid cancer Levothyroxine (life long) to keep TSH levels low Radiation therapy for metastasis New molecular drugs
rare complications from thyroid surgery Damage recurrent laryngeal nerve (≤ 2%) Accidental removal parathyroids (≤ 2%)
after thyroid surgery, the pt will require Life long drug therapy for hypothyroidism
prognosis of thyroid surgery depends on on cell type, spread
normal adrenal function includes hypothalamus, pituitary, adrenal glands
normally, the hypothalamus sends sends corticotropin-releasing hormone (CRH) to the pituitary gland
when CRH is sent to the pituitary gland, it causes the pituitary to secrete adreno-corticotropin hormone (ACTH)
when the pituitary gland secretes ACTH, it stimulates the adrenal glands
when the adrenals are stimulated, they respond by respond by releasing cortisol, aldosterone and dehydroepiandosterone into the bloodstream
where are the adrenals located just above the kidneys
cortisol levels rise with stress
adrenal insufficiency addison's disease
cause of addison's disease destruction / dysfunction adrenal cortex due to: Gradual atrophy gland function (idiopathic) Autoimmune disease Corticosteroid Therapy
Corticosteroid Therapy causes addison's disease because synthetic cortisol is going to increase cortisol levels so the adrenal gland is going to produce less cortisol
Corticosteroid Therapy does not increase steroid dose with stress ex= infection, surgery long term steroids need to be decreased
Corticosteroid Therapy that is too abruptly tapered can cause adrenal insufficiency
symptoms of adrenal insufficiency (mild) Lethargy, confusion, depression, weakness, hypoglycemia, hyponatremia, hyperkalemia, nausea, vomiting !! hyperpigmentation !!
there is hypoglycemia, hyponatremia, hyperkalemia from adrenal insufficiency because there is an aldosterone deficiency
adrenal crisis symptom = shock
diagnosis of addisons disease Morning serum cortisol concentration ACTH Stimulation Test
Morning serum cortisol concentration: normal Normal- Cortisol levels higher in morning 6AM cortisol (10-20 mcg/dL)
Morning serum cortisol concentration: low cortisol is suggestive of If low (< 3mcg/dL – strongly suggestive of adrenal insufficiency
ACTH Stimulation Test is when blood cortisol, urine cortisol or both are measured before and after a synthetic form of ACTH is given by injection
ACTH Stimulation Test: normal rise in blood and urine cortisol levels
ACTH Stimulation Test: little or no increase of cortisol is suggestive of adrenal insufficiency
Acute Adrenal Insufficiency management is important because condition can be life threatening
acute Adrenal Insufficiency management increase steroid dose (oral or IV) Monitor fluid/electrolytes Quiet environment, no stress
for pts with acute adrenal insufficiency, it is important to Teach self-care
self care for pts with acute adrenal insufficiency Increase steroid dosage stress, surgery, illness Do not stop steroids abruptly Vomiting – call or IM dose (self administer) Medic alert bracelet Emergency kit on hand (Addisonian Crisis)
Cushing’s Syndrome
occurs when Prolonged exposure high levels cortisol
cause of Cushing’s Syndrome Body produces too much cortisol or iatrogenic
Body might produce too much cortisol because of Pituitary or adrenal tumor
iatrogenic cause of Cushing’s Syndrome Long term use of oral corticosteroids
Because oral steroids affect the entire body, they cause systemic SE
Longer use & higher doses increase risk of oral steroids systemic SE
oral steroids systemic SE Glaucoma Fluid retention Hypertension Mood swings Cataracts High blood glucose levels Increased risk of infection Osteoporosis Buffalo hump Thin skin, easy bruising and slower wound healing
Buffalo hump Fat deposits in abdomen, face and back of neck
cushings syndrome risks longer use or corticosteroids
what type of corticosteroids causes a greater risk oral causes greater risk over inhaled meds
nursing management of cushings syndrome Adhere to established dosage Suggest monitoring of bone density Explain may cause emotional lability Recognize when dosage may need increased Taper as prescribed, if possible
make sure pts are aware of these signs infection delayed healing easy bruising
Created by: leh195
 

 



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