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EPID midterm
| Question | Answer |
|---|---|
| What is Epidemiology | Study of the distribution and determinants of disease in populations and applying it to prevent disease |
| what are the main goals of Epidemiology | Describe disease patterns, identify causes, prevent disease, and evaluate interventions. |
| What is descriptive epidemiology? | Study of disease distribution without comparison groups (person, place, time). |
| What is analytic epidemiology? | Study of disease causes using comparison groups (exposed vs unexposed, cases vs controls). |
| Difference between association and causation? | Association = relationship; causation = exposure causes disease. |
| What is incidence? | Number of NEW cases in a population over time. |
| What is prevalence? | What is prevalence? |
| Formula for prevalence? | Prevalence = Incidence × Duration |
| What is risk (cumulative incidence)? | Probability of developing disease. |
| What is the formula for risk | Risk = New cases / Population at risk |
| What is incidence rate (incidence density)? | Number of new cases per person-time. |
| What is the formula of Rate? | Rate = New cases / Person-time |
| What is person-time? | Total time people are at risk in study. |
| What is an example of person - time? | 100 people × 1 year = 100 person-years |
| What is a case report? | Study of one patient. |
| What is a case series? | Study of multiple patients with same disease. |
| What is a cross-sectional study? | Measures exposure and disease at one point in time. |
| What is an ecological study? | Study using group-level data instead of individual data. |
| What is ecological fallacy? | Group data does not represent individual risk. |
| What is a cohort study? | Study that follows exposed and unexposed people over time to see who develops disease. |
| Cohort studies start with what? | Exposure status. |
| Main measure used in cohort studies? | Risk Ratio (Relative Risk) |
| Risk Ratio formula? | RR = Risk in exposed / Risk in unexposed |
| Interpretation of RR = 1 | No association. |
| Interpretation of RR > 1 | Exposure increases risk. |
| Interpretation of RR < 1 | Exposure is protective. |
| What is a case-control study? | Study comparing cases (disease) and controls (no disease) to assess past exposure. |
| Case-control studies start with what? | Disease status. |
| Main measure used in case-control studies? | Odds Ratio (OR) |
| Odds Ratio formula? | OR = (A × D) / (B × C) |
| Interpretation of OR = 1 | No association. |
| Interpretation of OR > 1 | Exposure increases risk. |
| Interpretation of OR < 1 | Exposure is protective. |
| Why can't risk be calculated in case-control studies? | Because researchers choose number of cases and controls. |
| When does OR approximate RR? | When disease is rare (<5%). |
| Primary prevention definition? | Prevent disease before it occurs. |
| Example of Primary prevention? | Vaccines |
| Secondary prevention definition? | Early detection. |
| Example of Secondary prevention? | Screening tests |
| Tertiary prevention definition? | Reduce complications. |
| Example of Tertiary prevention? | Rehabilitation |
| What is a reservoir? | Where disease normally lives. |
| What is a vector? | Organism that spreads disease (mosquito). |
| What is a fomite? | Object that spreads disease. |
| Endemic definition? | Disease always present. |
| Epidemic definition? | Sudden increase in disease. |
| Pandemic definition? | Worldwide epidemic. |
| Passive surveillance definition? | Doctors report disease cases. |
| Active surveillance definition? | Public health actively searches for cases. |
| Mean definition? | Average value. |
| Median definition? | Middle value. |
| Correlation coefficient range? | −1 to +1 |
| Correlation coefficient meaning? | Strength and direction of relationship. |
| What is disease prevalence influenced by? | Incidence and duration of disease |
| Prevalence formula? | P=I*D |