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resp meds

QuestionAnswer
Corticosteroid (nasal spray) meds Budesonide (Rhinocort)  Fluticasone (Flonase)  Mometasone (Nasonex)  Triamcinolone (Nasocort)
Corticosteroid action, side effects, care Decrease inflammation, inhibits leukotrienes & interleukins, promote mucociliary action  Used in allergic rhinitis, sinusitis Side effects: nasal irritation, mucosal drying, nosebleeds  Teach: daily adherence, takes days to weeks for max effect
Mast cell stabilizer (nasal, neb) Cromolyn (NasalCrom)  Action  Stabilize mast cells thereby decrease inflammation and bronchoconstriction  Used in allergic rhinitis
Mast cell stabilizer (nasal, neb) considerations Use caution with renal and hepatic impairment  Side effects: HA, nasal irritation, sneezing, throat irritation, unpleasant taste, epistaxis  Use bronchodilators 30 mins before cromolyn
LEUKOTRIENE RECEPTOR ANTAGONIST Montelukast (Singulair)  Action  Leukotriene released in response to allergen which cause inflammation, bronchoconstriction, & mucous production, this drug blocks this action  Used in allergic rhinitis, asthma, COPD
LEUKOTRIENE RECEPTOR ANTAGONIST considerations May take 1 wk before therapeutic  Side effect: HA, possible dizziness  Monitor liver functions  Not for acute asthma attacks
ANTIHISTAMINES 1st Generation  Diphenhydramine (Benadryl)  Hydroxyzine (Vistaril)  Chlorpheniramine  2nd Generation  Loratadine (Claritin)  Cetirizine (Zyrtec)  Fexofenadine (Allegra)  Azelastine (Astelin) nasal spray
ANTIHISTAMINES action Block or inhibit histamine at receptors but not production  Bronchial smooth muscle relaxation, decreased secretions, reduce itching  Used in many disorders (allergic rhinitis, allergic reactions, COPD, asthma)
ANTIHISTAMINES considerations Side effects: CNS depression (drowsiness) or stimulation (anxiety/paradoxical excitement) in 1st generation, anticholinergic effects  Oral admin onset 15-60 mins  Avoid other CNS depressants  Adverse effects: Seizures, dysrhythmias, allergy skin te
Decongestants (nasal or oral) Pseudoephedrine (Sudafed)  Phenylephrine (Neo-Synephrine)  Oxymetazoline (Afrin)
Decongestants (nasal or oral) action Shrink swollen nasal mucous membranes, sympathomimetics cause vasoconstriction = dec. blood flow = dec. swelling  Used in allergic rhinitis, pharyngitis, nasal congestion
Decongestants (nasal or oral) considerations Contraindicated in HTN & CAD  Side effects: nasal irritation/dryness, rebound congestion, nervousness, tremors, insomnia, tachycardia, hypertension  Nasal for 3 days then switch to oral  Avoid caffeine and increase fluid intake
Expectorants Guaifenesin (Robitussin, Mucinex)  Action  Reduces viscosity of secretions  Used in upper resp disorders, cough, asthma, pneumonia, COPD, CF
Expectorants considerations Caution in elderly and respiratory insufficiency  Side effects: GI upset, dizziness  Increase fluid intake  Must cough effectively to work
Antitussives (oral tab/liquid) Benzonatate (Tessalon)  Dextromethorphan (Robitussin DM)  Guaifenesin w/ Codeine (opioid)  Action  Suppress cough reflex through CNS suppression (opiod) or without (non-opiod)
Antitussives considerations Opioid: respiratory depression, addiction, contraindicated in liver or renal disease, seizures  Nonopioid: Dextromethorphan contraindicated in asthma & emphysema  Side effects: dizziness, drowsiness, dry mouth, dysuria
MUCOLYTICS Acetylcysteine (Mucomyst)  Action  Liquefy respiratory secretions, treat acetaminophen overdose  Nursing Considerations  Not commonly used  Max effect in 5-10 mins  Side effect: bronchospasm, oral irritation, HA  Foul smell
BRONCHODILATORS Albuterol (Proventil, Ventolin) short acting  Levalbuterol (Xopenex) short acting  Salmeterol (Serevent) long acting
BRONCHODILATORS action Stimulate beta2 adrenergic receptors causing bronchodilation  Used in asthma, COPD
BRONCHODILATOR considerations Side Effects: tachycardia, nausea, anxiety, tremors, insomnia, restlessness, anorexia  Watch for hypokalemia & hyperglycemia  Administer properly & teach patient  Bronchodilator before corticosteroid  Rinse mouth out after admin
Anticholinergics Ipratropium (Atrovent) short acting  Tiotropium (Spiriva) long acting  Action  Blocks action of acetylcholine in bronchial smooth muscles
Anticholinergics considerations Approved for COPD, severe asthma attacks  Used cautiously in pts with glaucoma or prostate enlargement  Side effects: Dry oral membranes, cough, urinary retention, temporary blurred vision with eye contact
METHYLXANTHINES Aminophylline  Theophylline  Action  Inhibit phosphodiesterase = inc cAMP = bronchodilation  Used in chronic conditions: COPD, asthma
METHYLXANTHINES considerations  Watch for toxicity: restlessness, insomnia, irritable, tremors, N/V, seizures  High incidence of drug interaction and side effects  Side effects: nausea, headache, insomnia, GI distress, tachycardia, dysrhythmias, seizures  Avoid caffeine
SYSTEMIC CORTICOSTEROIDS (ORAL, IM, IV) Hydrocortisone (Solu-Cortef)  Methylprednisolone (Solu-Medrol)  Prednisone  Action  Steroid hormone that has anti-inflammatory and immunosuppressive activity  Used in asthma, COPD, pneumonia
SYSTEMIC CORTICOSTEROIDS considerations Give with food to minimize GI side effects  Glucose monitoring  Side effects: euphoria, headache, psychosis, insomnia, edema, delayed wound healing, osteoporosis, bone fractures, hyperglycemia
PNEUMONIA VACCINE who should get it Age ≥65  Age 2-64 with chronic health problems or dec immunity  Age 19-64 who smoke or have asthma
PNEUMONIA VACCINE effects Prevnar13, Pneumovax23 (IM)  Side effects: pain, redness, and swelling at injection site, mild fever, fatigue, headache, chills, or muscle pain
FLU VACCINE Trivalent or Quadrivalent inactivated influenza vaccine (IM)  Injection, approved for >6months of age  Do NOT give:  Previous serious allergy or reaction to flu vaccine  Allergy to chicken or egg products  Side effects: site reaction
Live attenuated influenza vaccine (nasal spray) Nasal spray  Approved for healthy people ages 2-49  Side effects: runny nose, congestion
INFLUENZA MEDICATIONS Antivirals -vir  Oseltamivir (Tamiflu)  Zanamivir (Relenza)  Baloxavir marboxil (Xofluza)
INFLUENZA considerations Watch liver & kidney function  Increase fluid intake  Side effect: dry mouth, dizziness, drowsiness, mood/mental changes  Do not give Xofluza with dairy or calcium
ANTIBIOTICS Penicillins (beta-lactams) -cillin  Amoxicillin (Amoxil)  Amoxicillin/clavulanate (Augmentin)  Penicillin G  Penicillin V  Pipercillin/tazobactam (Zosyn)
ANTIBIOTICS considerations Assess allergies  Thick IM preparation  Decreased efficacy of birth control pills  Take on empty stomach  Side/adverse effect: GI upset, diarrhea, hypo/hyperkalemia, blood dyscrasias
ANTIBIOTICS  Macrolides Azithromycin (Zithromax)  Clarithromycin (Biaxin)  Clindamycin (Cleocin
ANTIBIOTICS  Macrolides considerations Take on empty stomach  Watch liver dysfunction & renal dysfunction  Increase protein for therapeutic efficacy  Watch for ototoxicity: dizzy, vertigo, tinnitus
ANTIBIOTICS  Fluoroquinolones Moxifloxacin (Avelox)  Levofloxacin (Levaquin)  Ciprofloxacin (Cipro)
ANTIBIOTICS  Fluoroquinolones considerations Give 2 hours from antacids, iron, and zinc, or sucralfate Increase protein, Change positions slow : HA, lethargy, fatigue, restlessness, elevated liver enzymes, photosensitivity  Teach: protection from sun and reporting unusual joint or muscle pain
ANTIBIOTICS  Cephalosporins Ceftriaxone (Rocephin)  Cefazolin (Ancef)  Cefuroxime (Ceftin)  Cephalexin (Keflex)
ANTIBIOTICS  Cephalosporins considerations Cross sensitivity to PCNs  Monitor renal function  Give 2 hours from iron  Deep IM  May take with food  Watch inc. PT/INR  Inc. fluids and protein  Avoid alcohol
ANTIBIOTICS  Carbapenems Imipenem/cilastatin (Primaxin)  Meropenem (Merrem)  Ertapenem (Invanz)
ANTIBIOTICS  Carbapenems considerations Watch for seizures  Monitor renal, hepatic, neuro- toxicities  Deep IM
ANTIBIOTICS  Aminoglycosides Gentamycin  Neomycin  Nephro-, Neuro-, Ototoxicities  Monitor peak and trough  May be taken with food if GI upset treat severe aerobic Gram-negative bacterial infections, such as sepsis and endocarditis, by inhibiting bacterial protein synthesis
Glycopeptide Vancomycin  treat infections in many different parts of the body (bone infections, infective endocarditis, lower respiratory tract infection  Nephrotoxic and Ototoxic  Monitor peak and trough  IV: risk for phlebitis, central line preferred  Sid
TUBERCULOSIS MEDICATIONS Antituberculins  Rifampin  Isoniazid (INH)
TUBERCULOSIS MEDICATIONS considerations Monitor liver function  Hepato, nephro, ototoxicity  NO alcohol: inc risk for hepatitis  Encourage B vitamins  Must take full course  Rifampin: discolor urine, tears, saliva, stains clothing  INH: take 1 hr before meals
Created by: cwehner125
 

 



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