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CNS 4
| Category | Generic | Brand | Indications | EK | Classification |
|---|---|---|---|---|---|
| Anticonvulsant | carbamazepine (PO) | Tegretol | Seizure disorders, bipolar disorder | SE: Dizziness, drowsiness, headache, ataxia, N/V, hyponatremia. BBW: Serious dermatologic reactions (SJS/TEN) with genetic predisposition; aplastic anemia & agranulocytosis. | |
| Anticonvulsant | lamotrigine (PO) | Lamictal | Seizure disorders, bipolar disorder | Key Side Effects: nausea, vomiting, somnolence, skin rash, alopecia US Boxed Warnings: risk of serious dermatologic reactions, including SJS | |
| Anticonvulsant | divalproex (valproic acid derivative) (PO) | Depakote, Depakote ER | Seizure disorders, bipolar disorder, migraine prophylaxis | Key Side Effects: drowsiness, weight gain, tremor, alopecia, thrombocytopenia, hyperammonemia US Boxed Warnings: may cause fatal hepatic failure; may cause life- threatening pancreatitis; fetal toxicity | |
| Anticonvulsant | topiramate (PO) | Topamax | Seizure disorders, migraine prophylaxis | Key Side Effects: somnolence, dizziness, memory impairment, weight loss | |
| Anticonvulsant | levetiracetam (PO,IV) | Keppra | Seizure disorder | Key Side Effects: somnolence, dizziness, nausea, vomiting, weakness, asthenia, psychotic symptoms, agitation | |
| Anticonvulsant | oxcarbazepine (PO) | Trileptal | Seizure disorder | Key Side Effects: somnolence, dizziness, diplopia, nausea, vomiting, ataxia, hyponatremia | |
| Anticonvulsant | gabapentin (PO) | Neurontin | Seizure disorder, neuropathic pain | Key Side Effects: somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision, peripheral edema, weight gain | |
| Anticonvulsant | pregabalin (PO) | Lyrica | Seizure disorder, neuropathic pain | xerostomia, blurry vision, peripheral edema, weight gain | CS-V |