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control gene express
| Question | Answer |
|---|---|
| The distinct characteristics of different cell types in a multicellular organism result mainly from the differential regulation of the | transcription of genes transcribed by RNA polymerase II. |
| ___ -DNA interactions are among the tightest and most specific in molecular biology. | protein |
| An _____ is a group of bacterial genes that are transcribed from a single promoter | operon |
| The function of the genes that are part of the tryptophan operon are to | repressible inducible |
| What is the signal that activates the Trp repressor so it can bind to the operator? | tryptophan |
| When cellular tryptophan levels are high, the Trp operon is turned off. | True |
| The Lac operon is regulated by which of the following: | glucose and lactose |
| The ___ is the expanse of DNA involved in regulation of transcription including the promotor and other regulatory sequences. | gene control region |
| How are most eukaryotic transcription regulators able to affect transcription when their binding sites are far from the promoter? | by looping out the intervening DNA between their binding site and the promoter |
| ___ activators are eukaryotic transcription regulators that bind to DNA packed away as heterochromatin in order to recruit other proteins regulators to modify the chromatin, making it available for transcription. | pioneer |
| Combinatorial control of gene expression | involves groups of transcription regulators working together to determine the expression of a gene. |
| ___ alter chromatin by modifying lysines in the tail of histone proteins to allow greater accessibility to the underlying DNA | histone acetyltransferases |
| ___ is triggered when a stop codon is detected between exon junction proteins in a test round of translation. | non-sense mediated decay |
| During the cytosolic degradation of mRNA, in ___ decay the deadenylating enzyme DAN shortens the polyA tail while in ___ decay a specific nuclease recognizes the UTR and rapidly degrades the mRNA. | deadenylation-dependent; deadenylation-independent |
| miRNA | regulate gene expression |
| siRNA | defense again foreign RNA |
| piRNA | triggers promotion of heterochromatin |
| The long noncoding RNA Xist | is important for the formation of highly condensed heterochromatin on the X chromosome. |