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AC AP and Throm
anticoagulant antiplatelet and thrombolytic drugs
| Question | Answer |
|---|---|
| Anticoagulants | Warfarin-interferes with Vitamin K clotting factors Heparin-inhibits formation of fibrin clots |
| Anticoagulants Action | prevent the formation of a clot by inhibiting certain clotting factors |
| Anticoagulants Uses | DVT prophylaxis, treatment of DIC, Clotting Prevention and prevention of Thromboembolism esp. in A-Fib. |
| Anticoagulants Adverse Reactions | Bleeding, Hematoma, Bruising and Thrombocytopenia |
| Anticoagulants Nursing Considerations | wear med alert bracelet, monitor for bleeding and bruising, avoid unnecessary injections or injury, double check doses and alert provider prior to surgery |
| Anticoagulants Oral | Warfain-Vitamin K Antidote |
| Anticoagulant Perenteral | Heparin and Lovenox-Protamine Sulfate Antidote |
| Anticoagulant Labs | CBC, PT, INR, Platelet Count |
| Antiplatelet Drugs | Aspirin, Clopidogrel (Plavix), Cilostazol (Pletal), Dipyridamole Aggrenox), Anagrelide(Agrylin) |
| Antiplatelet Uses | Acute Coronary Syndrome, Thrombocythemia, Recent MI or Stroke |
| Antiplatelet Contraindications | Thrombocytopenia, Active Bleeding, Recent Stroke, GI Ulcers, Leukemia, Vitamin K deficiency |
| Antiplatelet Considerations | Monitor CBC and platelet count, high infection and bleeding risk, take medication exactly as directed and AVOID ALCOHOL |
| THROMBOLYTICS Examples | Alteplase (Activase) Reteplase (Retavase) and Tenecteplase(TNKase) all end in LASE |
| THROMBOLYTICS Uses | Acute Ischemic Stroke, Acute MI, PE or DVT, Central Venous Catheter Occlusions |
| THROMBOLYTICS ACTION | break down fibrin clots they are CLOT BUSTERS |
| HOW LONG IS THE WINDOW FOR ADMINITERING CLOT BUSTER AFTER STROKE | 2 HOURS |
| WHAT IS THROWING A CLOT A RISK OR | STROKE |
| MONA | M=morphine; O=giving oxygen; N= give nitro 3 pills 5 min apart for up to 15 minutes; A=ASA(asprin) |
| APAP | tylenol |
| ASA | asprin |
| THROMBOLYTICS ADVERSE REACTIONS | BLEEDING MAJOR RISK |
| THROMBOLYTICS NURSING CONSIDERATIONS | monitor VS and EKG, assess neuro status for stroke risk, Monitor H&H, platelet, Plasminogen, Double check dosage |