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From DNA to Protein
| Term | Definition |
|---|---|
| central dogma of molecular biology | doctrine that genetic instructions in DNA are copied by RNA, which carries them to a ribosome where they are used to synthesize a protein (DNA>RNA>protein) |
| Chargaff's rules | observations by Erwin Chargaff that concentrations of the four nucleotide bases differ among species; and that, within a species, the concentrations of adenine and thymine and the concentrations of cytosine and guanine are always about the same |
| messenger RNA | type of RNA that copies genetic instructions from DNA in the nucleus and carries them to the cytoplasm |
| ribosomal RNA | type of RNA that helps form Ribosomes and assemble proteins |
| transfer RNA | type of RNA that brings amino acids to Ribosomes where they are joined together to form proteins |
| codon | group of three nitrogen bases in nucleic acids that makes up a code "word" of the genetic code and stands for an amino acid, start, or stop |
| genetic code | universal code of three-base codons that encodes the genetic instructions for the amino acid sequence of proteins |
| promoter | region of a gene where a RNA polymerase binds to initiate transcription of the gene |
| protein synthesis | process in which cells make proteins that includes transcription of DNA and translation or mRNA |
| transcription | process in which genetic instrcutions in DNA are copied to form a complementary strand of mRNA |
| translation | process in which genetic instructions in mRNA are "read" to synthesize a protein |
| chromosomal altercation | mutation that changes chromosome structure |
| frame shift mutation | deletion or insertion of one or more nucleotides that changes the reading frame of the genetic material |
| genetic disorder | disease caused by a mutation in one or a few genes |
| germline mutation | mutation that occurs in gametes |
| mutagen | environmental factors that causes mutations |
| mutation | change in the sequence of bases in DNA or RNA |
| point mutation | change in a single nucleotide base in the genetic material |
| somatic mutation | mutation that occurs in cells of the body other than gametes |