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chapter 6.0
BIO
| Term | Definition |
|---|---|
| central dogma of molecular biology | DNA → RNA → Protein Discovering this sequence of events was a major milestone in molecular biology. |
| messenger RNA (mRNA) | type of RNA that copies genetic instructions from DNA in the nucleus and carries them to the cytoplasm |
| ribosomal RNA (rRNA) | ribosomal RNA (rRNA) |
| transfer RNA (tRNA) | brings amino acids to ribosomes, where they are joined together to form proteins. |
| codon | group of three nitrogen bases in nucleic acids that makes up a code “word” of the genetic code and stands for an amino acid, start, or stop |
| genetic code | universal code of three-base codons that encodes the genetic instructions for the amino acid sequence of proteins |
| promoter | region of a gene where a RNA polymerase binds to initiate transcription of the gene |
| protein synthesis | process in which cells make proteins that includes transcription of DNA and translation of mRNA |
| transcription | process in which genetic instructions in DNA are copied to form a complementary strand of mRNA |
| translation | translation |
| chromosomal alteration | mutation that changes chromosome structure |
| frameshift mutation | deletion or insertion of one or more nucleotides that changes the reading frame of the genetic material |
| genetic disorder | disease caused by a mutation in one or a few genes |
| germline mutation | mutation that occur in gametes |
| mutagen | environmental factors that causes mutations |
| mutation | change in the sequence of bases in DNA or RNA |
| point mutation | change in a single nucleotide base in the genetic material |
| somatic mutation | mutation that occurs in cells of the body other than gametes |
| Chargaff’s rules | observations by Erwin Chargaff that concentrations of the four nucleotide bases differ among species; and that, within a species, the concentrations of adenine and thymine |
| are always about the same and the concentrations of cytosine and guanine are always about the same |