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Stack #4627117
| Question | Answer |
|---|---|
| What neurotransmitters do ANTIDEPRESSETS affect? | norepinephrine, serotonin, dopamine |
| What neurotransmitters do ANTIPSYCHOTICS affect? | dopamine and serotonin |
| What neurotransmitters do BENSODIAZEPINES affect? | depress GABA/CNS |
| What neurotransmitters do PSYCHOSTIMULANTS affect | norepinephrine, dopamine, stimulate CNS |
| What are the big 3 anti-"HAM" and their ADRS? | 1. antiHistamines - sedation and weight gain 2. antiAdrenergics - hypotenson and dizziness 3. antiMuscarinic - can't see, can't spit, can't pee, can't shit |
| What are main Monoamine oxidase neurotransmitters? | 1. serotonin 2. dopamine 3. norephinephrine |
| How do psychotropic meds affect neurotransmission? | 1. activating receptors 2. blocking receptors 3. blocking reuptake |
| What causes side effects? | medications binding to unneeded receptors |
| Most enzymes get metabolized in liver -> CYP 450 | |
| What do interactions with certain foods or other drugs do to enzymes? | 1. induce 2. inhibit |
| What is the MAO of Benzodiazepines? | depress CNS and POTENTIATE effects of GABA - PRN |
| "-pam" = benzo - GABE IS RAISED BY ALCOHOL (if cold turkey = deadly seizures) | |
| Types of antioclytics | 1. Benzodiazepines 2. Buspirone/Buspar 3. SSRI |
| Buspirone | Non-benzo, not addictive, not as effective - TAKE DAILY |
| SSRI | LONG-TERM! 1st line med for anxiery! |
| ADRs of benzos | - tolerance and dependence - TAPER OFF = seizures - drowsy and confusion - orthostatic hypotension - paradoxical excitement in ELDERLY |
| ANTIDEPRESSENTS | 1. MAOIs: many food and drug interaction, HTN CRISIS 2. SSRIs 3. SNRIs 4. TCAs |