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GI 1

CategoryGenericBrandCommon IndicationsClassificationEK
Anticholinergic; Antispasmodic dicyclomine (PO) Bentyl IBS Key Side Effects: drowsiness, blurred vision, dizziness, xerostomia, constipation Other Notes: CI in gastrointestinal obstruction, reflux esophagitis, acute hemorrhage with cardiac instability, obstructive uropathy, glaucoma
Guanylate cyclase C agonist linaclotide (PO) Linzess IBS-C, opioid-induced constipation Key Side Effects: diarrhea, abdominal pain US Boxed Warnings: do not use in patients <2 years of age (risk of death due to dehydration) Other Notes: contraindicated in mechanical gastrointestinal obstruction
Osmotic laxative polyethylene glycol 3350 (PO) Miralax Constipation OTC Key Side Effects: abdominal cramping, electrolyte imbalance Other Notes: CI with bowel obstruction
Osmotic laxative Lactulose (PO) Enulose, Constulose Constipation, hepatic encephalopathy Key Side Effects: abdominal cramps, abdominal distention, diarrhea, flatulence
Stimulant laxative senna (PO) Ex-Lax, Senokot Constipation OTC Key Side Effects: abdominal cramping, electrolyte imbalance
Stool softener docusate (PO) Colace Prevent straining during defecation OTC Other Notes: do not use with mineral oil
Corticosteroid dexamethasone (PO,IV) DexPak, DoubleDex Inflammatory diseases, cerebral edema, CINV Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use
Corticosteroid methylprednisolone (PO,IM,IV) Medrol, Solu-Medrol Inflammatory diseases, COPD /Asthma exacerbation, acute gout Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use
Corticosteroid prednisolone (PO) Orapred Inflammatory diseases, COPD /Asthma exacerbation, acute gout Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use
Corticosteroid prednisone (PO) Deltasone, Rayos Inflammatory diseases, COPD /Asthma exacerbation, acute gout Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use
Corticosteroid hydrocortisone (PO,IV,Topical) Topical: Corsair IV: Solu-Cortef Topical: Inflammation, rash PO/IV: Acute illness, adrenal insufficiency Key Side Effects: hyperglycemia, increased appetite with weight gain, depression, irritability, anxiety, restlessness, insomnia, osteoporosis (chronic use), Cushing's syndrome (chronic use) Other Notes: risk of adrenal suppression with prolonged use
Created by: jcresend
 



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