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| Pharmacologic category | Generic | Brand | Classification | Common Indication |
|---|---|---|---|---|
| Alpha 2 agonist | brimonidine (ophthalmic) | Alphagan P, Lumify | Lumify: OTC | Elevated IOP, Ocular redness |
| Non-selective beta-bocker | timolol (ophthalmic) | Timoptic, Tmoptic XE, Istalol | Elevated IOP | |
| Prostaglandin analog | brimatoprost (ophthalmic) | Lumigan, Latisse | Elevated IOP, eyelash hypotrichosis | |
| Prostaglandin analong | latanoprost (ophthalmic) | Xalatan, Xelpros, lyuzeh | Elevated IOP | |
| Calcineurin inhibitor | cyclosporin (ophthalmic) | Restasis | Keratoconjunctivitis sicca | |
| Pediculocide | permethrin (topical) | Nix, Elimite | Nix: OTC | Lice, scabies |
| Retinoic acid derivate | adapalene (topical) | Differin | OTC | Acne |
| Antiseptic | chlorhexidine (topical, PO) | Hibiclens, Peridex | Hibiclens: OTC | Skin cleanser, periodontitis, gingivitis |
| Corticosteroid | clobetasol (topical) | Temovate, Clobex | Psoriasis, atopic dermatitis | |
| Expectorant | guaifenesin (PO) | Mucinex, Robitussin, Robafen | OTC | cough |
| antitussive | dextromethorphan (PO) | Delsym | OTC | cough |
| antitussive | benzonatate (PO) | Tessalon Perles | cough | |
| antimanic agent | lithium (PO) | Lithobid | Bipolar disorder | |
| antimigraine | sumatriptan (PO, intranasal, SQ) | Imitrex | Migraine | |
| antimigraine | rizatriptan (PO) | Maxalt | Migraine | |
| First-generation antipsychotic | haloperidol (PO, IV, IM) | Haldol | Schizophrenia | |
| Second-generation antipsychotic | clozapine (PO) | Clozaril | Treatment-resistant schizophrenia | |
| Second-generation antipsychotic | aripiprazole (PO, IM) | PO/IM: Abilify; IM: Aristada | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants | |
| Second-generation antipsychotic | quetiapine (PO) | Seroquel, Seroquel XR | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | |
| Second-generation antipsychotic | lurasidone (PO) | Latuda | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | |
| Second-generation antipsychotic | olanzapine (PO, IM) | Zyprexa | Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) | |
| Second-generation antipsychotic | risperidone (PO, IM) | PO: Risperdal IM: Risperdal Consta | Schizophrenia | |
| Alpha 2 agonist | tizanidine (PO) | Zanaflex | Spasticity | |
| Aminoquinolone | hydroxychloroquine (PO) | Plaquenil | RA, SLE, malaria | |
| NSAID | diclofenac (topical) | Voltaren Gel | OTC | OA |
| NSAID | diclofenac (PO) | Voltaren | OA, RA, acute pain | |
| NSAID | ibuprofen (PO) | Motrin, Advil | OTC | OA, RA, acute pain |
| NSAID | meloxicam (PO) | Mobic | OA, RA, acute pain | |
| NSAID | indomethacin (PO) | Indocin | OA, RA, acute pain, gout | |
| NSAID | naproxen (PO) | Naprosyn, Anaprox, Aleve | OTC | OA, RA, acute pain, gout |
| NSAID | ketorolac (PO) | Toradol | Pain | |
| NSAID, COX-2 selective | celecoxib (PO) | Celebrex | OA, RA, acute pain | |
| Skeletal muscle relaxant | cyclobenzaprine (PO) | Flexeril, Amrix, Fexmid | muscle spasm | |
| Skeletal muscle relaxant | baclofen (PO) | spasticity | ||
| Skeletal muscle relaxant | methocarbamol (PO) | Robaxin | muscle spasm | |
| Transdermal topical analgesic IV: antiarrhythmic | lidocaine (transdermal, IV) | Transdermal: Lidoderm, IV: Xylocaine | Transdermal: OTC | Transdermal: pain, IV: ventricular arrhythmias |
| Antigout agent | colchicine (PO) | Colcrys | Gout | |
| Xanthine oxidase Inhibitor | allopurinol (PO) | Zyloprim | Gout | |
| Depolarizing neuromuscular blocking agent | succinylcholine (IV) | Anectine | Neuromuscular blockade for intubation or procedures | |
| Anti-tumor necrosis factor alpha inhibitor | etanercept (SQ) | Enbrel | RA | |
| Anti-tumor necrosis factor alpha inhibitor | adalimumab (SQ) | Humira | RA, Crohn's Disease, Ulcerative Colitis | |
| Inhaled corticosteroid (ICS) | budesonide (INH) | Pulmicort | Asthma, COPD | |
| Inhaled corticosteroid (ICS) | fluticasone propionate (INH) | Flovent, Arunity | Asthma, COPD | |
| Inhaled corticosteroid (ICS) and long-acting beta 2 agonist (LABA) | fluticasone and salmeterol (INH) | Advair, Wixela | Asthma, COPD | |
| Inhaled corticosteroid (ICS) and long-acting beta 2 agonist (LABA) | budesonide and formoterol (INH) | Symbicort, Breyna | Asthma, COPD | |
| Inhaled corticosteroid (ICS) and long-acting beta 2 agonist (LABA) | mometasone and formoterol (INH) | Dulera | Asthma, COPD | |
| Inhaled corticosteroid (ICS), long-acting beta 2 agonist (LABA), and long-acting muscarinic antagonist (LAMA) | umeclidinium + vilanterol + fluticasone (INH) | Trelegy Ellipta | Asthma, COPD | |
| Long-acting muscarinic antagonist (LAMA) | tiotropium (INH) | Spiriva | Asthma, COPD | |
| Short-acting beta 2 agonist (SABA) | albuterol (INH) | Proventil, Ventolin, ProAir | Asthma, COPD | |
| Leukotriene receptor antagonist | montelukast (PO) | Singulair | Allergic rhinitis, asthma | |
| Partial nicotine agonist | varenicline (PO) | Chantix | Smoking cessation | |
| Anticonvulsant | carbamazepine (PO) | Tegretol | Seizure disorders, bipolar disorder | |
| Anticonvuslant | lamotrigine (PO) | Lamictal | Seizure disorders, bipolar disorder | |
| Anticonvulsant | divalproex (valproic acid derivative) (PO) | Depakote, Depakote ER | Seizure disorders, bipolar disorder, migraine prophylaxis | |
| Anticonvulsant | topiramate (PO) | Topamax | Seizure disorders, migraine prophylaxis | |
| Anticonvulsant | levetiracetam (PO, IV) | Keppra | Seizure disorders | |
| Anticonvulsant | oxcarbazepine (PO) | Trileptal | Seizure disorders | |
| Anticonvulsant | gabapentin (PO) | Neurontin | Seizure disorders, neuropathic pain | |
| Anticonvulsant | pregabalin (PO) | Lyrica | CS-V | Seizure disorders, neuropathic pain |
| Antianxiety agent | buspirone (PO) | Buspar | Anxiety | |
| Benzodiazepine | alprazolam (PO) | Xanax | CS-IV | Anxiety |
| Benzodiazepine | clonazepam (PO) | Klonopin | CS-IV | Anxiety, seizure disorders |
| Benzodiazepine | diazepam (PO, IV) | Valium | CS-IV | Anxiety, seizure disorders, acute alcohol withdrawal |
| Benzodiazepine | lorazepam (PO, IV) | Ativan | CS-IV | Anxiety, seizure disorders, acute alcohol withdrawal |
| Benzodiazepine | midazolam (IV, IM) | Versed | CS-IV | Anesthesia, sedation |
| Hypnotic | zolpidem (PO) | PO: Ambien, Ambien CR SL: Edluar | CS-IV | Insomnia |
| Sleep aid | melatonin (PO) | OTC | Insomnia, jet lag | |
| Sedative, general anesthetic | propofol (IV) | Diprivan | Sedation for mechanical ventilation, procedural anesthesia, status epilepticus | |
| Alpha 2 agonist, sedative | dexmedetomidine (IV) | Precedex | Sedation for mechanical ventilation or procedures | |
| Alpha 1 agonist | pseudoephedrine (PO) | Sudafed | OTC | Nasal congestion |
| Corticosteroid | fluticasone (intranasal) | Flonase | OTC | Allergic rhinitis |
| Corticosteroid | triamcinolone (intransal) | Nasacort | OTC | Allergic rhinitis |
| Histamine H1 blocker | azelastine (intranasal) | Astepro | OTC | Allergic rhinitis |
| Histamine H1 blocker | diphenhydramine (PO, IV) | Benadryl | PO: OTC | Allergic rhinitis, allergic reaction, insomnia |
| Histamine H1 blocker | hydroxyzine (PO, IV) | Atarax, Vistaril | Pruritus, nausea, anxiety | |
| Histamine H1 blocker | cetirizine (PO) | Zyrtec | OTC | Allergic rhinitis |
| Histamine H1 blocker | loratadine (PO) | Claritin | OTC | Allergic rhinitis |
| Histamine H1 blocker | fexofenadine (PO) | Allegra | OTC | Allergic rhinitis |
| Histamine H1 blocker` | levocetirizine (PO) | Xyzal | OTC | Allergic rhinitis |
| Histamine H1 blocker | olopatadine (ophthalmic) | Pataday, Patanol | OTC | Allergic conjunctivitis |
| Histamine (H1) blocker and opioid analgesic | promethazine and codeine (PO) | Phenergan with Codeine | CS-V | Cough |
| Opioid analgesic and expectorant | codeine and guaifenesin (PO) | Robitussin AC, Cheratussin AC | CS-V | Cough |
| Anticholinergic; Antispasmodic | dicyclomine (PO) | Bentyl | IBS | |
| Guanylate cyclase C agonist | linaclotide (PO) | Linzess | IBS-C, opioid-induced constipation | |
| Osmotic laxative | polyethylene glycol 3350 (PO) | MiraLax | OTC | Constipation |
| Osmotic laxative | Lactulose (PO) | Enulose, Constulose | Constipation, hepatic encephalopathy | |
| Stimulant laxative | senna (PO) | Ex-Lax, Senokot | OTC | Constipation |
| Stool softener | docusate (PO) | Colace | OTC | Prevent straining during defecation |
| Corticosteroid | dexamethasone (PO, IV) | DexPak, DoubleDex | Inflammatory diseases, cerebral edema, CINV | |
| Corticosteroid | methylprednisolone (PO, IM, IV) | Medrol, Solu-Medrol | Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout | |
| Corticosteroid | prednisolone (PO) | Orapred | Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout | |
| Corticosteroid | prednisone (PO) | Deltasone, Rayos | Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout | |
| Corticosteroid | hydrocortisone (PO, IV, topical) | Topical: Cortaid IV: Solu-Cortef | Topical: OTC | Topical: Inflammation, rash PO/IV: Acute illness, adrenal insufficiency |
| Histamine (H2) antagonist | famotidine (PO, IV) | Pepcid, Zantac 360 | PO: OTC | GERD, erosive esophagitis, SUP |
| Dopamine (D2) antagonist | metoclopramide (PO, IV) | Reglan | Gastroparesis, GERD, nausea, vomiting | |
| Selective serotonin (5-HT3) antagonist | ondansetron (PO, IV) | Zofran | Nausea, vomiting | |
| Histamine (H1) antagonist | promethazine (PO, IM, IV, PR) | Phenergan | Motion sickness, nausea, vomiting | |
| Histamine (H1) antagonist | meclizine (PO) | Bonine | OTC | Motion sickness, vertigo |
| Antidiarrheal | diphenoxylate and atropine (PO) | Lomotil | CS-V | Diarrhea |
| Proton pump inhibitor (PPI) | dexlansoprazole (PO) | Dexilant | GERD, PUD, erosive esophagitis, SUP | |
| Proton pump inhibitor (PPI) | esomeprazole (PO, IV) | Nexium | PO: OTC | GERD, PUD, erosive esophagitis, SUP |
| Proton pump inhibitor (PPI) | lansoprazole (PO) | Prevacid | OTC | GERD, PUD, erosive esophagitis, SUP |
| Proton pump inhibitor (PPI) | omeprazole (PO) | Prilosec | OTC | GERD, PUD, erosive esophagitis, SUP |
| Proton pump inhibitor (PPI) | pantoprazole (PO, IV) | Protonix | GERD, PUD, erosive esophagitis, SUP | |
| Gastrointestinal protectant | sucralfate (PO) | Carafate | duodenal ulcers | |
| Angiotensin-converting enzyme (ACE) inhibitor | benazepril (PO) | Lotensin | HTN, HF, CAD | |
| Angiotensin-converting enzyme (ACE) inhibitor | enalapril (PO) | Vasotec | HTN, HF, CAD | |
| Angiotensin-converting enzyme (ACE) inhibitor | lisinopril (PO) | Prinivil, Zestril | HTN, HF, CAD | |
| Angiotensin-converting enzyme (ACE) inhibitor | ramipril (PO) | Altace | HTN, HF, CAD | |
| Angiotensin II receptor blocker (ARB) | irbesartan (PO) | Avapro | HTN, HF, CAD | |
| Angiotensin II receptor blocker (ARB) | losartan (PO) | Cozaar | HTN, HF, CAD | |
| Angiotensin II receptor blocker (ARB) | olmesartan (PO) | Benicar | HTN, HF, CAD | |
| Angiotensin II receptor blocker (ARB) | valsartan (PO) | Diovan | HTN, HF, CAD | |
| ARB and Neprilysin inhibitor (ARNI) | valsartan and sacubitril (PO) | Entresto | HF | |
| Dihydropyridine calcium channel blocker (CCB) | amlodipine (PO) | Norvasc | HTN, CAD | |
| Dihydropyridine calcium channel blocker (CCB) | nifedipine ER (PO) | Procardia XL, Adalat CC | HTN, CAD | |
| Dihydropyridine calcium channel blocker (CCB) | nicardipine (PO, IV) | Cardene | Hypertensive crisis | |
| Non-dihydropyridine CCB | diltiazem (PO, IV ) | Cartia XT, Cardizem CD, Cardizem LA, Cardizem, Tiazac | AF(rate control), HTN, CAD | |
| Non-dihydropyridine CCB | verapamil (PO) | Calan SR, Verelan | AF(rate control), HTN, CAD | |
| Thiazide diuretic | hydrochlorothiazide (PO) | HTN | ||
| Thiazide-related diuretic | chlorthalidone (PO) | Thalitone | HTN | |
| See individual drug components | amlodipine and benazepril (PO) | Lotrel | ||
| See individual drug components | lisinopril and hydrochlorothiazide (PO) | Zestoretic | ||
| See individual drug components | losartan and hydrochlorothiazide (PO) | Hyzaar | ||
| See individual drug components | olmesartan and hydrochlorothiazide (PO) | Benicar-HCT | ||
| See individual drug components | valsartan and hydrochlorothiazide (PO) | Diovan-HCT | ||
| Mineralocorticoid receptor antagonist (MRA) | spironolactone (PO) | Aldactone | HTN, HF, ascites | |
| Loop diuretic | furosemide (PO, IV) | Lasix | Volume overload | |
| Loop diuretic | torsemide (PO) | Soaanz | Volume overload | |
| Beta1- selective beta blocker | atenolol (PO) | Tenormin | AF (rate control), CAD, HTN | |
| Beta1- selective beta blocker | metoprolol succinate (PO) | Toprol-XL | HF, AF (rate control), CAD, HTN | |
| Beta1- selective beta blocker | nebivolol | Bystolic | HTN | |
| Beta1- selective beta blocker | esmolol (IV) | Brevibloc | HTN, AF(rate control), hypertensive emergency | |
| Non-selective beta-blocker and alpha 1 blocker | carvedilol (PO)` | Coreg, Coreg CR | HF, AF(rate control), CAD, HTN | |
| Non-selective beta-blocker and alpha 1 blocker | labetalol (PO, IV) | Trandate | PO: HT, IV: hypertensive crisis | |
| Non-selective beta blocker | propranolol (PO) | Inderal LA, Inderal XL | HTN, CAD, migraine prophylaxis | |
| Alpha 2 agonist | clonidine (PO, transdermal) | PO: Catapres, Transdermal: Catapres-TTS | HTN, ADHD | |
| Direct arterial vasodilator | hydralazine (PO, IV) | HTN | ||
| Beta1, beta2, and alpha1 agonist | epinephrine (IV, IM, SQ) | Adrenalin, EpiPen | Advanced cardiac life support, shock, anaphylaxis, bradycardia | |
| Alpha1 agonist (predominantly), beta1 and beta2 agonist | norepinephrine (IV) | Levophed | Shock | |
| Anticoagulant, direct thrombin inhibitor | dabigatran (PO) | Pradaxa | AF(stroke prevention), VTE | |
| Anticoagulant, factor Xa inhibitor | apixaban (PO) | Eliquis | AF(stroke prevention), VTE | |
| Anticoagulant, factor Xa inhibitor | rivaroxaban (PO) | Xarelto | AF(stroke prevention), VTE, PAD | |
| Anticoagulant, vitamin k antagonist | warfarin (PO) | Coumadin, Jantoven | AF(stroke prevention), VTE | |
| Anticoagulant, low molecular weight heparin | enoxaprin (SQ) | Lovenox | ACS, VTE | |
| Anticoagulant | heparin (IV, SQ) | ACS, VTE | ||
| Antiplatelet agent | clopidogrel (PO) | Plavix | CAD, stroke | |
| Antiplatelet agent | ticagrelor (PO) | Brilinta | ACS | |
| Antiplatelet agent | aspirin (PO) | Bayer, Bufferin, Ecotrin | OTC | ACS, stable angina, pain, stroke |
| Vasodilator | nitroglycerin (SL) | Nitrostat | ACS, stable angina | |
| Fibrinolytic | alteplase (intracatheter, IV) | Intracatheter: Cathflo Activase, IV: Activase | Intracatheter: catheter clearance, IV: STEMI, acute ischemic stroke, PE | |
| Biguanide | metformin (PO) | Fortamet, Glumetza | Type 2 DM, PCOS | |
| Dipeptidyl peptidase (DPP-4) inhibitor | sitagliptin | Januvia, Zituvio | Type 2 DM | |
| Sodium-glucose cotransporter inhibitor 2 (SGLT2 inhibitor) | empagliflozin (PO) | Jardiance | Type 2 DM, HF, CKD | |
| Sodium-glucose cotransporter inhibitor 2 (SGLT2 inhibitor) | dapagliflozin (PO) | Farxiga | Type 2 DM, HF, CKD | |
| Sulfonylurea | glimepiride (PO) | Glucotrol, Glucotrol XL | Type 2 DM | |
| Thiazolidinedione (TZD) | pioglitazone (PO) | Actos | Type 2 DM | |
| Glucagon-like peptide-1 (GLP-1) receptor agonist | dulaglutide (SQ) | Trulicity | Type 2 DM | |
| Glucagon-like peptide-1 (GLP-1) receptor agonist | liraglutide (SQ) | Victoza, Saxenda | Type 2 DM, chronic weight management | |
| Glucagon-like peptide-1 (GLP-1) receptor agoinst | semaglutide (PO, SQ) | SQ: Ozempic , Wegovy PO: Rybelsus | Type 2 DM, chronic weight management | |
| Dual GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) agonist | tirzepatide (SQ) | Mounjaro, Zepbound | Type 2 DM, chronic weight management | |
| Insulin, long acting | insulin glargine (SQ) | Lantus, Toujeo, Basaglar | Type 1 DM, type 2 DM | |
| Insulin, intermediate acting | insulin NPH (SQ) | Humulin N, Novolin N | OTC | Type 1 DM, type 2 DM |
| Insulin, rapid acting | insulin apart (SQ) | Novolong | Type 1 DM, type 2 DM | |
| Insulin, rapid acting | insulin lispro (SQ) | Humalog | Type 1 DM, type 2 DM | |
| Insulin, short acting | insulin regular (SQ, IV) | Humulin R, Novolin R | SQ: OTC | Type 1 DM, type 2 DM, DKA |
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