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Microbio L1
| Question | Answer |
|---|---|
| Microbes: | cellular, living, microorganisms |
| Prokaryotes: | no nucleus or organelles |
| Eukaryotes: | nucleus, cellular organelles |
| Pathogen: | a microbe that can cause disease |
| Not all microbes are pathogens!! | Some exist as part of the microbiota Some are critical for environmental processes Many don't meaningfully interact with humans |
| Pasteur’s experiment | Used swan necked flasks, so nothing can get into them but air This disapproved the spontaneous generation theory |
| 4 steps to prove that a microbe causes a disease | Identify Isolate Inoculate (inject virus with healthy mice to see if it becomes sick) Re-isolate |
| What are some problems as to finding out how microve cause a disease? | Some microbes don't cause disease in every individual Many microbes can’t be grown in pure culture Come microbes only infect humans (can’t ethically test) |
| Aseptic Technique: | methods to prevent transmission of microbes (not sterility) |
| Semmelweis: | evidence that handwashing prevents maternal mortality during birth |
| Nightingale: | popularized medical handwashing, and medical statistics |
| Lister: | aseptic practices during surgery |
| Taxonomy: | naming and organizing organisms |
| What are the 3 domains of life? | Bacteria- uni prok Eukarya- uni and multi euk Archae- uni prok (weird |
| Strain: | two microbes of the same species, but with slight genetic differences to alter behavior |
| Symbiosis | any close relationship between two different species |
| Mutualism: | both partners benefit (+/+) Could be microbiota |
| Commensalism: | one benefits while the other is unharmed (+/0) Could be microbiota |
| Parasitism: | one benefits while the other is harmed (+/-) Could be pathogens and parasites |
| Microbiota- | microbial populations that live on or in a larger organism |
| Resident: | seeded at birth or from environment and maintained |
| Biofilms are | extremely resistant to removal and antibiotics |
| Transient: | exposure from environment, don’t stay around |
| Importance of Microbiota | Trains the immune system Digesting certain nutrients (fiber) Synthesizing some components (vitamins, serotonin) Preventing infection Use up nutrients pathogens would like Disruptions to microbiome can cause issues |