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ACS and MI
| Question | Answer |
|---|---|
| Umbrella term for unstable angina or acute MI. Caused by myocardial oxygen supply-demand imbalance. | |
| Stable Angina | Chest pain with exertion/stress, relieved by rest or nitroglycerin. Predictable pattern. |
| Unstable Angina | Chest pain at rest or increasing severity/duration. Pre-infarction angina. Medical emergency. |
| Variant Angina | Prinzmetal angina. Caused by coronary artery spasm, often at rest. |
| Myocardial Infarction | Heart muscle necrosis from prolonged ischemia. Pain unrelieved by rest/NTG >15 min. |
| ACS Risk Factors | HTN, hyperlipidemia, DM, smoking, sedentary lifestyle, stress, atherosclerosis. |
| MI Sx: Chest Pain | Crushing, substernal pressure radiating to shoulder/jaw. Described as tight, squeezing. |
| MI Sx: Atypical | Females/older adults: dyspnea, indigestion, fatigue, confusion. May lack classic pain. |
| Cardiac Enzymes: Troponin | Most specific for MI. Rises in 3-4 hrs, peaks 24-36h, remains elevated 7-14 days. |
| Cardiac Enzymes: CK-MB | Rises 4-6h, peaks 24h, returns to baseline in 72h. Specific to cardiac muscle. |
| Cardiac Enzymes: Myoglobin | Earliest marker (1-3h), not cardiac-specific. Returns to normal in 24h. |
| ECG in Ischemia | ST depression and/or T wave inversion indicates myocardial ischemia. |
| ECG in Injury | ST segment elevation indicates myocardial injury (e.g., STEMI). |
| ECG in Infarction | Pathologic Q waves develop, indicating necrosis. Permanent change. |
| Nitroglycerin Use | SL tablet for angina. Up to 3 doses 5min apart. Causes headache (vasodilation). |
| MI Emergency Care | Call 911, administer aspirin, O2, morphine, monitor VS/ECG, prep for reperfusion. |
| Reperfusion Therapy | PCI (angioplasty/stent) or thrombolytics ("clot-busters") to restore coronary flow. |
| Post-MI Monitoring | Continuous cardiac monitoring, assess for dysrhythmias, heart failure, cardiogenic shock. |
| MI Complications | Dysrhythmias, HF, cardiogenic shock, pericarditis, ventricular rupture, death. |
| Cardiac Rehab | Structured exercise, education, counseling post-MI to reduce risk, improve health. |
| Lifestyle Modifications | Smoking cessation, heart-healthy diet, regular exercise, stress management, med adherence. |