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3.3a
| Question | Answer |
|---|---|
| One of the most important functions of ----- is to control the passage of materials into and out of the organelles and the cell as a whole. | cellular membranes |
| The plasma membrane is both a barrier and gateway between the cytoplasm and ECF. | It is selectively permeable—it allows some things through, such as nutrients and wastes, but usually prevents other things, such as proteins and phosphates, from entering or leaving the cell. |
| The methods of moving substances through the membrane can be classified in two overlapping ways: | as passive or active mechanisms and as carrier-mediated or not. |
| Passive mechanisms require no energy (ATP) expenditure by the cell. | In most cases, the random molecular motion of the particles themselves provides the necessary energy. |
| Passive mechanisms | include filtration, diffusion, and osmosis. |
| Active mechanisms | , however, consume ATP. These include active transport and vesicular transport. |
| Carrier-mediated mechanisms use a membrane protein to transport substances from one side of the membrane to the other | but some transport processes, such as osmosis, do not involve carriers. |
| Filtration is a process in which a physical pressure forces fluid through a selectively permeable membrane. A coffee filter is an everyday example. | The weight of the water drives water and dissolved matter through the filter, while the filter holds back larger particles (the coffee grounds). |
| In physiology, the most important case of filtration is seen in the blood capillaries, where blood pressure forces fluid through gaps in the capillary wall (Fig. 3.13). | This is how water, salts, nutrients, and other solutes are transferred from the bloodstream to the tissue fluid and how the kidneys filter wastes from the blood. |
| Capillaries hold back larger particles such as blood cells and proteins. In most cases, water and solutes filter through narrow gaps between the capillary cells. | In some capillaries, however, the cells have large filtration pores through them, like the holes in a slice of Swiss cheese, allowing for more rapid filtration of large solutes such as protein hormones. |
| Blood pressure | in capillary forces water and small solutes such as salts through narrow clefts between capillary cells. |
| Filtration Through the Wall of a Blood Capillary. | Water and small solutes pass through gaps between cells, while blood cells and other large particles are held back. |