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CV 1-4/CNS 5
| Pharm category | Generic name | Brand name | Common indications | Essential Knowledge | Classification |
|---|---|---|---|---|---|
| ACE inhibitor | Benazepril (PO) | Lotensin | HTN,HF,CAD | Key SE: cough, hyperkalemia, angioedema, hypotension US BW: FETAL TOX (CI in pregnancy) | |
| ACE inhibitor | Enalapril (PO) | Vasotec | HTN,HF,CAD | Key SE: cough, hyperkalemia, angioedema, hypotension US BW: FETAL TOX (CI in pregnancy) | |
| ACE inhibitor | Lisinopril (PO) | Prinivil, Zestril | HTN,HF,CAD | Key SE: cough, hyperkalemia, angioedema, hypotension US BW: FETAL TOX (CI in pregnancy) | |
| ACE inhibitor | Ramipril (PO) | Altace | HTN,HF,CAD | Key SE: cough, hyperkalemia, angioedema, hypotension US BW: FETAL TOX (CI in pregnancy) | |
| ARB | Losartan (PO) | Cozaar | HTN,HF,CAD | Key SE: cough, hyperkalemia, angioedema, hypotension US BW: FETAL TOX (CI in pregnancy) | |
| ARB | Olmesartan (PO) | Benicar | HTN,HF,CAD | Key SE: cough, hyperkalemia, angioedema, hypotension US BW: FETAL TOX (CI in pregnancy) | |
| ARB | Valsartan (PO) | Diovan | HTN,HF,CAD | Key SE: cough, hyperkalemia, angioedema, hypotension US BW: FETAL TOX (CI in pregnancy) | |
| ARB and Neprilysin inhibitor (ARNI) | Valsartan & Sacubitril (PO) | Entresto | HF | Key SE: hyperkalemia, angioedema, hypotension US BW: FETAL TOX | Dont use w/in 36 hrs of an ACE inhibitor |
| dihydropyridine CCB | amlodipine (PO) | Norvasc | HTN, CAD | Key SE: peripheral edema, hypotension | |
| dihydropyridine CCB | nifedipine ER (PO) | Procardia XL, Adalat CC | HTN, CAD | Key SE: peripheral edema, hypotension | |
| dihydropyridine CCB | Nicardipine (PO, IV) | Cardene | hypertensive crisis | flushing, headache, peripheral demea, hypotension | |
| non-dihydro CCB | Diltiazem (PO,IV) | Cartia XT, Cardizem CD, Cardizem LA, Cardizem Tiazac | AF (rate control), HTN, CAD | Key SE: bradycardia, constipation, peripheral edema, hypotension | |
| non-dihydro CCB | Verapamil (PO) | Calan SR, Verelan | AF (rate control), HTN, CAD | Key SE: bradycardia, constipation, peripheral edema, hypotension | |
| Thiazide-related diuretic | Chlorthalidone (PO) | Thalitone | HTN | Key SE: hypokalemia, hyponatermia, photosensitivity, hypotension | |
| Amlodipine and benazepril (PO) | Lotrel | ||||
| Lisinopril and hydrochlorothiazide (PO) | Benicar-HCT | ||||
| Valsartan and hydrochlorothiazide (PO | Diovan-HCT | ||||
| Olmesartan and Hydrochlorothiazide | Benicar-HCT | ||||
| Mineralocorticoid receptor antagonist (MRA) | Spironolactone (PO) | Aldactone | HTN.HF,asities | Key SE: gynecomastia, hyperkalemia, hypotension | |
| Loop diuretic | Furosemide (PO,IV) | Lasix | volume overload | Key SE: hypokalemia, hypomagnesemia, hyponatremia, hypotension US BW: fluid and electrolyte loss | |
| Loop diuretic | Torsemide (PO) | Sooanz | volume overload | Key SE: hypokalemia, hypomagnesemia, hyponatremia, hypotension | |
| Beta-1 selective beta blocker | atenolol (PO) | Tenormin | AF (rate control), CAD, HTN | Key SE: bradycardia, hypotension US BW: avoid abrupt DC Othernotes: masks symptoms of hypoglycemia | |
| Beta-1 selective beta blocker | Metoprolol tartrate (PO,IV) | Lopressor | AF (rate control), CAD, HTN | Key SE: bradycardia, hypotension US BW: avoid abrupt DC Othernotes: masks symptoms of hypoglycemia | |
| Beta-1 selective beta blocker | Metropolol succinate (PO) | Toprol -XL | HF, AF (rate control), CAD, HTN | Key SE: bradycardia, hypotension Other notes: masks symptoms of hypoglycemia | |
| Beta-1 selective beta blocker | Nebivolol (PO) | Bystolic | HTN | Key SE: bradycardia, hypotension Other notes: masks symptoms of hypoglycemia | |
| Beta-1 selective beta blocker | Esmolol (IV) | Brevibloc | HTN, AF (rate control) , hypertensive emergency | Key SE: bradycardia, hypotension OTher notes: mask sx of hypoglycemia CI with pulmonary HX | |
| Non-selective Beta blocker and alpha blocker | carvedilol (PO) | coreg, coreg CR | HF, AF (rate control), CAD, HTN | Key SE: bradycardia, hypotension Other notes: masks sx of hypoglycemia | |
| Non-selective Beta blocker and alpha blocker | Labetalol (PO,IV) | Trandate | PO: HTN IV: Hypertensive crisis | Key SE: bradycardia, hypotension Other notes: masks sx of hypoglycemia | |
| Non-selective Beta blocker | Propanolol (PO) | Inderal LA, Inderal XL | HTN, CAD, migraine prophylaxis | Hey SE: bradycardia & HTN Other notes: masks sx of hypoglycemia | |
| Alpha2 agonist | Clonidine (PO, transdermal) | PO: Catapres Transdermal:Catapress TTS | HTN, ADHD | Key SE: xerostomia, drowsiness, contact dermatitis (transdermal), hypotension US BW: avoid epidural use Other notes: do not DC abruptly; taper to reduce rebound HTN | |
| Direct arterial vasodilator | Hydralazine (PO, IV) | ------ | HTN | Key SE: Hypotension, drug induced lupus like syndrome CI in CAD | |
| Beta1, Beta2, & alpha 1 agonist | Epinepherine (IV, IM, SQ) | Adrenalin, Epipen | Advanced cardiac life support, shock, analyphaxis, bradycardia | Key SE: tachyarrythmias, peripheral ischemia, hyperglycemia | |
| Alpha 1 agonist (predominantly), beta1 and beta 2 agonist | norepinephrine (IV) | Levophed | Shock | Key SE: tachyarrythmias, peripheral ischemia US BW: extravasion (centra line admin is preferred) | |
| Anticoagulant direct thrombin inhibitor | dabigatran (PO) | Pradaxa | AF (stroke prevention), VTE | Key SE: bleeding, dyspepsia US BW: premature DC increases risk of thrombotic events; increased risk of epidural or spinal hematoma in pt undergoing spinal puncture | |
| Anticoagulant factor Xa inhibitor | Apixaban (PO) | Eliquis | AF (stroke prevention), VTE | Key SE: bleeding US BW: premature DC increases risk of thrombotic events, increased risk of epidural or spinal hematoma in pt undergoing spinal puncture | |
| Anticoagulant factor Xa inhibitor | Rivaroxaban (PO) | Xarelto | AF (stroke prevention), VTE | Key SE: bleeding US BW: premature DC increases risk of thrombotic events, increased risk of epidural or spinal hematoma in pt undergoing spinal puncture | |
| Anticoagulant vitamin K antagonist | Warfarin (PO) | Coumadin, Janotoven | AF (stroke prevention), VTE | Key SE: bleeding, skin necrosis US BW: bleeding risk Other notes: NAAROOWWW THERAPUTIC INDEX, dose dependent tablet colors | |
| Anticoagulant, LMWH | Enoxaparin (SQ) | Lovenox | ACS, VTE | Key SE: bleeding, HIT US BW: increased risk of epidural or spinal hematoma in patients undergoing spinal puncture Other notes: do not expel air buble from syringe prior to injection | |
| Anticoagulant | Heparin (IV, SQ) | ____ | ACS, VTE | Key SE: bleeding, hyperkalemia (chronic use), HIT | |
| Antiplatelet agent | Clopidogrel (PO) | Plavx | CAD, stroke | Key SE: bleeding US BW: diminished effectivness in poor metabolizers | |
| Antiplatelet agent | Ticagrelor (PO) | Brillanta | ACS | Key SE: bleeding, dyspnea US BW: significant, sometimes fatal bleeding; do not exceed asprin > 100 mg daily due to reduced ticagrelor effectivness | |
| Antiplatelet agent | Aspirin (PO) | Bayer, Bufferin, Ecotrin | ACS, stable angina, pain, stable | Key SE: dyspepsia, heartburn, bleeding Other notes: CI in NSAID or salicylate allergy, children and teenagers with viral infection (due to reyes syndrome) can cause tinnitus in salicylate overdose | OTC!!! |
| Vasodilator | Nitroglycerin (SL) | Nitrostat | ACS, stable angina | Key SE: Headache, flushing, syncope, dizziness Other notes: do not use with PDE-5 inhibitors; tachyphylaxis; can aggravate angina causes by hypertrophic cardiomyopathy | |
| Fibrinolytic | Alteplase (intracatherter, IV) | Intracath: cathflo activase IV: Activase IV: stemi, acute ishcmeic stroke, PE | Intracath: Catheter clearance IV: STEMI, actue ischemic stroke, PE | Key SE: bleeding Other notes: CI in pt with severe uncontrolled HTN | |
| antiarrhythmic | Amiodarone ( PO,IV) | Pacerone, Nexterone | AF (rhythm control), V-fib, V-tach | Key SE: hypothyroidism, hyperthyroidism, pulm toxicity, hepatoxicity, epithelial keratopathy, photosensivity US BW: Intended only for life-threatening arrhythmias' pulmonary toxicity, heptatoxicity , proarrhytmic | |
| Cholesterol absorption inhibitor | Ezetimibe (PO) | Zetia | DLP | Key SE: myalgias, diarrhea | |
| Fibiric acid Derivative | Fenofibrate (PO) | Tricor, Trilipix | Hypertriglyceridemia | Key SE: Dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases | |
| Fibiric acid derivative | Gemfebrozil (PO) | Lopid | Hypertriglyceridemia | Key SE: Dyspepsia, myopathy/rhabdomyolysis, elevated hepatic transaminases | |
| HMG-COA reductase inhibitor | Atorvastatin (PO) | Lipitor | DLP, CAD, Stroke | Key SE: myopathy, rhabdomyolysis Other notes: avoid ecessive GFJ intake, avoid in preggers and BF | |
| HMG-COA reductase inhibitor | Lovastatin (PO) | Altoprev | DLP, CAD, Stroke | rhabdomyolysis Other notes: avoid ecessive GFJ intake, avoid in preggers and BF | |
| HMG-COA reductase inhibitor | Pravastatin (PO) | Pravachol | DLP, CAD, Stroke | rhabdomyolysis Other notes: avoid ecessive GFJ intake, avoid in preggers and BF | |
| HMG-COA reductase inhibitor | Rosuvastatin (PO) | Crestor | DLP, CAD, Stroke | rhabdomyolysis Other notes: avoid ecessive GFJ intake, avoid in preggers and BF | |
| HMG-COA reductase inhibitor | Simvastatin (PO) | Zocor | DLP, CAD, Stroke | rhabdomyolysis Other notes: avoid ecessive GFJ intake, avoid in preggers and BF | |
| Omega-3 Fatty acids | omega-3 ethyl esters (PO) | Lovaza | Hypertriglyceridema | Key SE: dyspepsia, eructation, fishy aftertaste Other notes: can prolong bleeding time when used with other meds that increase bleeding risk,use with caution if fish allergy | |
| Omega-3 Fatty acids | Icosapent ethyl | Vascepa | Hypertriglyceridema | Key SE: eructation, arthralgia Other notes: can prolong bleeding time when used with other meds that increase bleeding risk. Use with caution if allergic to fish | OTC: available RX: LOVAZA & VASCEPA |
Created by:
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