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Stack #4617523
| Question | Answer |
|---|---|
| What are Anti-depressants | They are medications use for depression and other indications |
| MOA for Anti-depressants | They increase certain neurotransmitter level to improve communication between nerve cells in order to strengthen the circuits which regulate mood. |
| Tricyclic Anti-depressants MOA | They block the reabsorption of serotonin and norepinephrine. They also affect "acetylcholine" and "histamine levels. |
| Tricyclic Anti-depressants (TCAs) EXAMPLE | Elavil ( Ami-triptyline ) Pamelor ( Nor-triptyline ) |
| Tetracyclic Anti-depressants (TeCA) MOA | Increase serotonin and norepinephrine and affect other neurotransmitters |
| Tetracyclic Anti-depressants (TeCA) EXAMPLE | Remeron ( Mirtazapine ) |
| Selective Serotonin Reuptake Inhibitors (SSRIs) USE | "Depression" and various type of "Anxiety - Related Disorders" |
| SSRIs MOA | They work by selectively blocking the reabsorption of "serotonin" it's the most popular class with less side effects. |
| SSRI's EXAMPLES | Prozac ( Flu-oxetine ) Paxil ( Par-oxetine ) Zolof ( Ser-traline ) Celexa ( Citalo-pram ) Lexapro ( Escitalo-pram ) |
| Serotonin Norepinephrine Reuptake Inhibitors (SNRIs) USE | Depression Anxiety disorders Nerve Pain Fibromyalgia |
| SNRIs MOA | Selectively blocking the reabsorption of "Serotonin" and "Norepinephrine" |
| SNRIs EXAMPLES | Effexor (Venla-faxine ) Cymbalta ( Dul-oxetine ) |
| Serotonin Antagonist & Reuptake Inhibitors (SARIs) USE | Insomia (off-label use) |
| SARIs MOA | SARIs has less selectivity; affect other "neurotransmitters". They block the binding of serotonin at certain undesired receptors and block serotonin reabsorption. |
| SARIs EXAMPLE | Desyrel ( Trazo-done ) |
| Norepinephrine Dopamine Reuptake Inhibitors (NDRIs) USE | "Depression" and Smoking cessation |
| NDRIs MOA | NDRIs work by selectively blocking the reabsorption of "norepinephrine" and "dopamine" |
| NDRIs EXAMPLE | Wellbutrin, Zyaban ( Bupropion ) |
| Benzodiazepines USE | "Anxiety" "insomnia" Seizure Muscle spasm They are DEA Schedule "IV" |
| Benzodiazepines MOA | Benzodiazepines work by enhancing the inhibitory neurotransmitter "Gamma-Aminobutyric Acid" (GABA) |
| Benzodiazepines for " Anxiety " | Xanax ( Alprazo-lam) Klonopin ( Clonaze-pam ) Ativan ( Loraze-pam ) Valium ( Diaze-pam ) They are DEA Schedule "IV" |
| Benzodiazepines For " Insomnia " | Restoril ( Temaze-pam ) |
| Non-Benzodiazepines For " Sleep aid " | Ambien ( Zolpidem ) They are DEA Schedule "IV" |
| Benzodiazepines " Anxiolytic" | Buspar ( Buspirone ) |
| Anti-psychotics USE | Use to treat: Schizophrenia Severe anxiety Psychosis ( delusions, hallucination & paranoia ) |
| Anti-psychotics MOA | Anti-psychotics blocks dopamine and serotonin receptors With two categories Typical ( 1st generation ) and Atypical ( 2nd generation ) |
| Anti-psychotics Typical First Generation | Might cause "Extrapyramidal Symptoms" (EPS) which are drug induced movement disorder affecting various parts of the body |
| Anti-psychotics Atypical 2nd generation | Block dopamine receptors more selectively, which causes less (EPS) side effects - causing more weight gain |
| Anti-psychotics Atypical "2nd generation" EXAMPLES | Risperdal ( Risperidone ) Seroquel ( Quetiapine ) Abilify ( Aripiprazole ) |
| Parkinson Disease Medications USE | Reduces: Tremor & Rigidity |
| Dopamine Precursor + Decarboxylase Inhibitor Combo "Parkinson Disease Medications" | Sinemet ( Levodopa + Carbidopa ) |
| Dopamine Agonist "Parkinson Disease Medications" | Mirapex ( Pramipexole ) Requip ( Ropinirole ) They are also use for "Restless Leg Syndrome" ( RLS ) |