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Ap Bio Mod 27-30
Ap Bio Module 27-30
| Question | Answer |
|---|---|
| P₁ | The original parents in a genetic cross; |
| F₁ | The offspring of the P1 cross; |
| monohybrid cross | A genetic cross that tracks one trait (one gene with two alleles), usually between heterozygous individuals -produces a 3:1 phenotype ratio in the F₂ generation. |
| Critical value | Threshold from chi-square table; if χ² (chi square) > critical value → reject null hypothesis. |
| Null hypothesis | Assumes no difference between observed and expected results. |
| Chi-square (χ²) | Tests if observed data fits expected ratios. |
| Incomplete dominance | when a Heterozygote genotype shows a phenotype that is the blend of the two alleles, - not full dominance. -Ex: Dominant flower color= Red , recessive= white flower color Heterozygous flower color= pink (mixture of the two) |
| Codominance | Both alleles are fully expressed in the heterozygote. Example: Blood type AB → both A and B antigens show. |
| Dihybrid cross | A genetic cross that tracks two traits (two genes), usually heterozygous for both. -Typical F₂ phenotype ratio: 9:3:3:1. |
| 9:3:3:1 ratio (from a dihybrid cross): | 9 → both dominant traits expressed (AABB) 3 → first dominant, second recessive (AAbb) 3 → first recessive, second dominant (aaBB) 1 → both recessive traits (aabb) -Occurs when Both parents are heterozygous for both traits Ex: (AaBb × AaBb). |
| Independent Assortment | Alleles for different genes separate independently during gamete formation. Explains why the 9:3:3:1 ratio appears—traits are inherited separately, not linked. |
| What does this mean in a pedigree? ⬛ | A male affected with a disease |
| What does this mean in a pedigree? ⬜ | A male that is not affected with a disease |
| What does this mean in a pedigree? ⚪ | A female not affected with the disease |
| What does this mean in a pedigree? ⚫ | A female affected with the disease |
| Pleiotropy | One gene affects multiple traits. Example: Sickle-cell allele affects blood shape, oxygen transport, and disease resistance. |
| Epistasis | One gene masks or modifies the expression of another gene. Ex:Mouse coat color: One gene determines fur color (black or brown). A second gene determines whether pigment is produced at all. |
| F₂ | The offspring produced by crossing F₁ individuals with each other. |
| Addition Rule (probability): | P(A or B)=P(A)+P(B)−P(A∩B) -use if problem says what is the probability that "either or happens" or "this or that happens" |
| Multiplication Rule (probability): | P(A and B)=P(A)×P(B) -use if asked "what is the probability that this and this happens" |
| When does 9:3:3:1 happen | -when genes are independently assorted (Mendelian Genetics only!) |
| Sex-linked genes: | Genes located on sex chromosomes (X or Y). Inheritance depends on the sex of the individual. |
| X-linked genes: | Located on the X chromosome. - Since males only 1 X while females have 2 Xs, males are more likely to get the disease as females can be carriers while males either have the disease or don't |
| Y-linked genes: | Located on the Y chromosome. Only males affected. |
| Describe the sex chromosomes provided by each parent during the production of haploid sex cells | Female offspring (XX):Receives one X chromosome from the mother and one X chromosome from the father Male offspring (XY): Receives one X chromosome from the mother and one Y chromosome from the father |
| Are there more X-linked or Y-Linked traits | -there are more X-linked traits so phenotypes usually come from the X chromosome. -Y chromosome has fewer genes than X chromosome so most traits come from the X and not the Y |
| Wild type (+) genotype | The “normal” or most common allele in a population Usually produces the standard phenotype (normal function) -noted as (+) |
| Mutant (c): | A variation of the gene that causes a different phenotype -less common than wild type - noted as "c" |
| SRY gene | Located on the Y chromosome Triggers male development by turning on genes that form testes Without the SRY gene female development occurs |
| How do you identify Y-linked genes on a pedigree? | Only males affected Passed father → son Appears in every generation in male line Females never show it |
| Linked genes | -Genes located on the same chromosome -Tend to be inherited together because they are physically close -The closer the genes, the less likely recombination separates them -Do not assort independently like Mendel’s genes |
| How do linked genes become unlinked form each other? | crossing over occurs during prophase I of meiosis, resulting in genes between homologous pairs switching places -thus one of the genes on one homolog ends up on another chromosome and is thus separated |
| Recombination | The exchange of genetic material between homologous chromosomes during meiosis Produces new combinations of alleles on the same chromosome |
| Recombination frequency (RF): | -Measures how often crossing-over occurs between two genes on the same chromosome -Genes that are closer to each other → lower RF -Genes that are farther apart→ higher RF (up to 50%) |
| Formula for recombination frequency | recombinants/total offspring x100 -used to map gene positons on a chromsome |
| How do you identify the recombinants in a genetics problems | - Look at the most common offspring phenotypes in a cross (they are usually the same as the parents) -Understand that any offspring showing allele combinations different from parents are recombinants -Parents: AB × ab - Recombinants= Ab or aB |