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TOXICOLOGY

Prelim

QuestionAnswer
It is the study of the adverse effects of chemical, physical, and biological on living organisms and ecosystem Toxicology
It is the study of adverse effects of xenobiotics Toxicology
5 scopes of biology (different branches) Biomedical Public Health Regulatory Environmental Clinical
Mechanism of action Biomedical
Effects of exposure Biomedical
Understanding biological responses through model toxic compounds Biomedical
Subtopics of biomedical: Mechanism of action Effects of exposure Understanding biological responses through model toxic compounds
Recognition and identification of hazards Public Health
Occupational exposure Public Health
Development and uses of pesticide Public Health
Subtopics of public health: Recognition and identification of hazards Occupational exposure Development and uses of pesticide
Development of exposure standards Regulatory
Detection methods Regulatory
Subtopics of regulator: Development of exposure standards Detection methods
Chemical effects on plants, animals, and ecosystem Environmental
Development of antidotes and treatments Clinical
Recognition of exposure Clinical
It is a mixture of science, art, and creative thinking Toxicology
The observational and data gathering phase Science
Utilization of the data to predict outcomes in humans based on in vitro and in vivo Art
Determining the next hypothesis and how to design experiments Creative thinking
It is important to note that facts are different from ______ Prediction
It plays an important role in the history of manking Poisons
Greek capital punishment Hemlock
Chinese poison arrows Aconite
Arrow with poison Curare
Experimented on criminals and himself King Mithridates VI of Pontus (Mithridates VI Eupator Dionysius)
He would drink a poison cocktail (36 ingredients) to prevent political enemies from being able yo poison him King Mithridates VI of Pontus (Mithridates VI Eupator Dionysius)
Agent to induce vomiting following poisonings Emetics
Tickle the mouth to reduce emesis Rusel
Suka with no laman Retch
Poisoning were so rampant in ____ Rome
A law was enacted in ______ 82 BC
Name of law that was enacted in 82BC Poisoning illegal and extended to careless dispenser of drugs
First classification of poisons use of emetics in treatment Dioscorides (Pedanius Dioscorides)
Paracelsus stated that ____ All substances are poison; there is none which is not a poison. The right dose differentiates a poison from a remedy.
Set the basics of pharmacology, toxicology and therapeutic Physician-alchemist
Full name of Maimonides: Moses ben Maimon
Concept of bioavailability based on the forms of toxicants or what one eats and drinks before ingestion Moses ben Maimon
Foods that can delay intestinal absorption Milk, butter, cream
Woman who sold arsenic-laces cosmetics Toffana
Provided services to local young soon to be widows Hieronyma spara
It is a primary toxic gent and a single chemical entity Toxicon
Systematic study of the effects of poison in the sick and poor to make sure the correct concoction was delivered to the customers Catherine de Medici
Rapidity of the toxic response Onset of action
Effectiveness of the compound Potency
Degree and specificity of response Site of action
Complaints of victims Clinical signs and symptoms
4 fundamental contributions: Experimentation is essential in the examination of responses The is a difference between the therapeutic and toxic properties The above are not easily determined, except by dose It is possible to ascertain a degree of specificity of chemicals
Responsible for the most famous saying in all of the toxicology Paracelsus (1493-1541)
Created by: kateperryy
 

 



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