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Organic Chemistry

Chapter 2 - A & P Lecture

QuestionAnswer
Macromolecules large, essential biological molecules ex: carbohydrates, lipids, proteins, nucleic acid
Carbohydrates - composed of C, H, O - divided into monosaccharides, disaccharides, polysaccharides - energy sources, structures, bulk for elimination - water soluble
Monosaccharides - building block of carbohydrates, simple sugars - 6 carbon sugars: (ex: glucose, fructose, galactose) important energy sources in diet - 5 carbon sugars: components of ATP, DNA, RNA
Disaccharides simple sugars bound together by a dehydration reaction ex: sucrose (glucose + fructose), lactose (glucose + galactose), maltose (2 glucose)
Polysaccharides long chains of many monosaccharides, storage molecules for monosaccharides and part of cell surface markers
Lipids - composed of C, H, O - insoluble in water - protection, insulation, physiological regulation, component of cell membrane, energy storage
Triglycerides (Fats) - ingested and broken down by hydrolysis - composed of glycerol and fatty acids - protection, insulation, energy source
Saturated Fatty Acids contains all single bonds in the carbon chain, which produces a more rigid structure; generally solid
Unsaturated Fatty Acids contains one (mono) or more (poly) double bonds in the carbon chain, which produces more relaxed structure, generally liquid
Trans Fats unsaturated fats that are artificially altered to be more saturated. are the highest cardiovascular risk fat.
Phospholipids one fatty acid replaced with a phosphate group, polar(hydrophilic) at one end and nonpolar (hydrophobic) at the other. - important structural component of cell membranes
Eicosanoids - derived from fatty acids - important regulatory molecules - ex: thromboxanes, leukotrienes, prostaglandins
Fat Soluble Vitamins nonpolar molecules essential for normal functioning
Steroids - lipids with 4 ring like structures - ex: cholesterol, bile salts, reproductive steroid hormones
Protein - composed C, H, O, N sometimes S - regulate processes, aid transport, protection, muscle contraction, structure, energy
Amino Acids - building blocks of proteins - general structure of a amino group, carboxyl group, hydrogen off the central carbon, R side (makes each amino acids different)
Peptide Bonds covalent bonds formed between amino acids during protein synthesis by dehydration
Primary Structure the amino acid sequence. a protein consists of a chain of different amino acids
Secondary Structure results from hydrogen bonding. the hydrogen bonds cause the amino acid chain to form pleated (folded) sheets or helices (coils)
Tertiary Structure large scale folding due to interactions within protein and surrounding environment which is generally water. polar regions tend to remain unfolded and in contact with water while nonpolar regions tend to fold inward away from water.
Denaturation change in shape caused by breaking of H bonds by heat or pH changes
Quaternary Structure results from the association of 2 or more proteins (subunits)
Nucleic Acids - composed of C, H, O, N, P - building blocks: nucleotides - ex: ATP, DNA, RNA
Nucleotides -deoxyribonucleic acid (DNA) & ribonucleic acid (RNA) - composed of a five carbon sugar (deoxyribose or ribose), a nitrogenous base, phosphate
DNA - genetic material - 2 strands of DNA nucleotides (A,T, G,C, held by H bonds) - double helix - antiparallel(opposite directions) 3' end & 5'
Gene sequence of bases that codes for synthesis of RNA or protein (base sequence determines the primary structure of a protein)
Adenosine Triphosphate (ATP) - stores/provides energy - all energy requiring chemical reactions stope when there is inadequate ATP
Catabolism of _____ and other nutrient molecules release ______ that is then stored in ____ glucose, energy, ATP ADP +Pi + energy -> ATP
Breakdown of ___ provides energy for ____ processes and to drive cell ______ ATP, anabolic, processes ATP -> ADP + Pi + energy
 

 



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