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DEENT 1, CNS, Pulmo

CNS 3, 4

Pharmacologic CategoryGenericBrandClassificationCommon IndicationKey Side Effects (EK)Other Notes (EK)US Boxed Warning (EK)
Alpha2 agonist brimonidine (ophthalmic) Alphagan P, Lumify Lumify: OTC Elevated IOP, ocular redness SE: ocular hypersensitivity, drowsiness, allergic conjunctivitis, conjunctival hyperemia, ocular pruritus CI with MAOI therapy
Non-selective beta-blocker timolol (ophthalmic) Timoptic, Timoptic XE, Istalol Elevated IOP SE: blurred vision, ocular stinging and burning
Prostaglandin analog bimatoprost (ophthalmic) Lumigan, Latisse Elevated IOP, eyelash hypotrichosis SE: eyelash growth, conjunctival hyperemia, ocular pruritus, iris color change, periocular hyperpigmentation, blurred vision
Prostaglandin analog latanoprost (ophthalmic) Xalatan, Xelpros, Iyuzeh Elevated IOP SE: eyelash growth, conjunctival hyperemia, ocular pruritus, iris color change, periocular hyperpigmentation, blurred vision
Calcineurin inhibitor cyclosporin (ophthalmic) Restasis Keratoconjunctivitis sicca SE: ocular burning, stinging, pruritus, foreign body sensation, hypersensitivity reaction
Pediculocide permethrin (topical) Nix, Elimite Nix: OTC Lice, scabies SE: itching, burning, redness, swelling of scalp
Retinoic acid derivative adapalene (topical) Differin OTC Acne SE: xeroderma, skin exfoliation, erythema, stinging, burning, pruritus
Antiseptic chlorhexidine (topical, PO) Hibiclens, Peridex Skin cleanser, periodontitis, gingivitis SE: dysgeusia, increased tartar formation, mouth discoloration, mouth irritation
Corticosteroid clobetasol (topical) Temovate, Clobex Psoriasis, atopic dermatitis SE: burning of skin, dryness of skin, hypopigmentation, secondary infection do not use for > 2 weeks because it may cause adrenal suppression
Expectorant guaifenesin (PO) Mucinex, Robitussin, Robafen OTC Cough SE: nausea, vomiting, dizziness, headache, diarrhea, stomach pain
Antitussive dextromethorphan (PO) Delsym OTC Cough SE: nausea, drowsiness, dizziness, constipation CI within 14 days of MAOI
Antitussive benzonatate (PO) Tessalon Perles Cough SE: sedation, nasal congestion, chills, chest numbness, bronchospasm Other: do not break capsule because it may cause choking do not break capsule because it may cause choking
Antimanic agent lithium (PO) Lithobid Bipolar disorder SE: tremor, acne, hypothyroidism, weight gain, polyuria, polydipsia, GI upset narrow therapeutic index drug (toxicity may occur at concentrations close to therapeutic range; therapeutic drug monitoring is recommended); avoid in pregnancy ability to promptly monitor levels is necessary
Antimigraine sumatriptan (PO, intranasal, SQ) Imitrex Migraine fatigue, somnolence, dizziness, chest tightness, paresthesias CI in ischemic heart diease, history of stroke or TIA, peripheral vascular disease, and uncontrolled hypertension
Antimigraine rizatriptan (PO) Maxalt Migraine fatigue, somnolence, dizziness, chest tightness, paresthesias CI in ischemic heart disease, history of stroke or TIA, peripheral vascular disease, and uncontrolled hypertension
First-generation antipsychotic haloperidol (PO, IV, IM) Haldol Schizophrenia sedation, EPS, parkinsonism, xerostomia, orthostatic hypotension, weight gain, QTc prolongation elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
Second-generation antipsychotic clozapine (PO) Clozaril Treatment-resistant schizophrenia sedation, constipation, orthostatic hypotension, sialorrhea, hyperglycemia, weight gain, neutropenia may cause severe neutropenia, orthostatic hypotension, bradycardia, syncope, seizures, fatal myocarditis and cardiomyopathy, elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
Second-generation antipsychotic aripiprazole (PO, IM) PO/IM: Abilify IM: Aristada Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) akathisia, restlessness, sedation, EPS, constipation, orthostatic hypotension, weight gain antidepressants increase the risk of suicidal thinking and behavior in children, adolescents and young adults, elderly patients with dementia-related psychosis related with antipsychotic drugs at increased risk of death
Second-generation antipsychotic quetiapine (PO) Seroquel, Seroquel XR Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) sedation, EPS, constipation, orthostatic hypotension, weight gain antidepressants increase the risk of suicidal thinking and behavior in children, adolescents and young adults, elderly patients with dementia-related psychosis related with antipsychotic drugs at increased risk of death
Second-generation antipsychotic lurasidone (PO) Latuda Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) sedation, EPS, constipation, orthostatic hypotension, weight gain CI with strong 3A4 inhibitors and inducers antidepressants increase the risk of suicidal thinking and behavior in children, adolescents and young adults; elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
Second-generation antipsychotic olanzapine (PO, IM) Zyprexa Schizophrenia, bipolar disorder, MDD (adjunct to antidepressants) sedation, EPS, xerostomia, constipation, orthostatic hypotension, weight gain, hyperglycemia elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
Second-generation antipsychotic risperidone (PO, IM) PO: Risperdal IM: Risperdal Consta Schizophrenia sedation, EPS, xerostomia, constipation, orthostatic hypotension, weight gain, hyperglycemia elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death
Anticonvulsant carbamazepine (PO) Tegretol Seizure disorders, bipolar disorder dizziness, drowsiness, headache, ataxia, nausea, vomiting, hyponatremia risk of serious dermatologic reactions (including SJS and TEN) in patients with certain genetic predisposition; may cause aplastic anemia and agranulocytosis
Anticonvulsant lamotrigine (PO) Lamictal Seizure disorders, bipolar disorder nausea, vomiting, somnolence, skin rash, alopecia risk of serious dermatologic reactions, including SJS
Anticonvulsant divalproex (valproic acid derivative) (PO) Depakote, Depakote ER Seizure disorders, bipolar disorder, migraine prophylaxis drowsiness, weight gain, tremor, alopecia, thrombocytopenia, hyperammonemia may cause fatal hepatic failure; may cause life-threatening pancreatitis; fetal toxicity
Anticonvulsant topiramate (PO) Topamax Seizure disorders, migraine prophylaxis somnolence, dizziness, memory impairment, weight loss
Anticonvulsant levetiracetam (PO, IV) Keppra Seizure disorders somnolence, dizziness, nausea, vomiting, weakness, asthenia, psychotic symptoms, agitation
Anticonvulsant oxcarbazepine (PO) Trileptal Seizure disorders somnolence, dizziness, diplopia, nausea, vomiting, ataxia, hyponatremia
Anticonvulsant gabapentin (PO) Neurontin Seizure disorders, neuropathic pain somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision, peripheral edema, weight gain
Anticonvulsant pregabalin (PO) Lyrica CS-V Seizure disorders, neuropathic pain somnolence, dizziness, ataxia, fatigue, diplopia, xerostomia, blurry vision, peripheral edema, weight gain
Inhaled corticosteroid (ICS) budesonide (INH) Pulmicort Asthma, COPD oral candidiasis, hoarseness (dysphonia), sore throat rinse mouth with water and spit out to prevent Candida infection
Inhaled corticosteroid (ICS) fluticasone propionate (INH) Flovent, Arnuity Asthma, COPD oral candidiasis, hoarseness (dysphonia), sore throat rinse mouth with water and spit out to prevent Candida infection
Inhaled corticosteroid (ICS) and long-acting beta2 agonist (LABA) fluticasone and salmeterol (INH) Advair, Wixela Asthma, COPD oral candidiasis, hoarseness (dysphonia), sore throat, nervousness, tremor, tachycardia, palpitations, hyperglycemia, decreased potassium rinse mouth with water and spit out to prevent Candida infection
Inhaled corticosteroid (ICS) and long-acting beta2 agonist (LABA) budesonide and formoterol (INH) Symbicort, Breyna Asthma, COPD oral candidiasis, hoarseness (dysphonia), sore throat, nervousness, tremor, tachycardia, palpitations, hyperglycemia, decreased potassium rinse mouth with water and spit out to prevent Candida infection
Inhaled corticosteroid (ICS) and long-acting beta2 agonist (LABA) mometasone and formoterol (INH) Dulera Asthma, COPD oral candidiasis, hoarseness (dysphonia), sore throat, nervousness, tremor, tachycardia, palpitations, hyperglycemia, decreased potassium rinse mouth with water and spit out to prevent Candida infection
Inhaled corticosteroid (ICS), long-acting beta2 agonist (LABA), and long-acting muscarinic antagonist (LAMA) umeclidinium + vilanterol + fluticasone (INH) Trelegy Ellipta Asthma, COPD xerostomia, nervousness, tremor, tachycardia, palpitations, hyperglycemia, decreased potassium, oral candidiasis, hoarseness (dysphonia), sore throat rinse mouth with water and spit out to prevent oral candidiasis (thrush)
Long-acting muscarinic antagonist (LAMA) tiotropium (INH) Spiriva Asthma, COPD xerostomia
Short-acting beta2 agonist (SABA) albuterol (INH) Proventil, Ventolin, ProAir Asthma, COPD tremor, tachycardia, nervousness, excitement, decreased potassium
Leukotriene receptor antagonist montelukast (PO) Singulair Allergic rhinitis, asthma headache risk of serious neuropsychiatric effects (i.e., serious behavior and mood-related changes, including suicidal thoughts and actions)
Partial nicotine agonist varenicline (PO) Chantix Smoking cessation nausea, vomiting, abnormal dreams, headache, insomnia, irritability
Created by: kapena5
 

 



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