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Stack #4603055
| Question | Answer |
|---|---|
| Are neurotransmitters hydrophilic or hydrophobic? | hydrophilic |
| Are steroid hormones hydrophilic or hydrophobic? | hydrophobic |
| Are peptide hormones hydrophilic or hydrophobic? | hydrophilic |
| Is insulin a hydrophilic or hydrophobic? | hydrophilic |
| Which type of hormone steroid or peptide can pass through the cell membrane. | Steroid |
| Which type of signalling has a receptor on the cell membrane- hydrophilic or hydrophobic | hydrophilic |
| Define signal transduction | When an extracellular signal is converted into an intracellular response |
| Describe what happens after when a peptide hormone binds to its receptor on the cell membrane. | A conformational change occurs in the receptor which transduces the signal into an intracellular response |
| State the two types of intracellular response in hydrophilic signalling | 1. phosphorylation kinase cascade 2. G protein activation |
| State the impact of intracellular signalling | enzyme activation OR opening/closing ion channels. |
| Can hydrophilic signals cross the membrane | no |
| Are hydrophobic signals polar or non polar | non polar |
| In hydrophobic signalling where are the receptors for the steroid hormones | cytoplasm or nucleus |
| When the steroid hormone binds to its receptor what happens next | a horomone receptor complex is formed which travels to the nucleus if not already there |
| State what the Horomone receptor complex does inside the nucleus | It binds to HRE within the DNA to influence the rate of transcription |
| Which type of diabetes is caused by failure to produce insulin from the pancreas | type 1 |
| Which type of diabetes is linked to obesity | type 2 |
| Describe the cause of type 2 diabetes | insulin receptor insensitivity at the liver |
| insulin receptor acts as a | kinase phosphorylating the next enzyme/protein in pathway |
| Explain why insulin is recommended to treat type 2 diabetes | improves glut 4 transporters recruitment to membrane |
| Describe what happens after phosphoryation kinase cascade | glut 4 recruited to membrane in vesicles |