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PHO 2
BDK
| Generic Name | Brand Name | Pharmacologic Category | Common Indications | Key Side Effects | Other Notes | US Boxed Warning | Classification |
|---|---|---|---|---|---|---|---|
| Hydrocodone/acetaminophen | Lortab, Vicodin, Norco | Opioid/nonopioid analgesic combination | Pain | Dizziness, Drowsiness, Nausea, Vomiting, Constipation, Pruritus, Respiratory depression (dose-related) | N/A | Use w/ CYP3A4 inhibitors (or stopping inducers) can increase concentrations; Hepatotoxicity See opioid analgesic BW | CS-II |
| Oxycodone/acetaminophen | Percocet, Endocet | Opioid/nonopioid analgesic combination | Pain | Dizziness, Drowsiness, Nausea, Vomiting, Constipation, Pruritus, Respiratory depression (dose-related) | N/A | Use w/ CYP3A4 inhibitors (or stopping inducers) can increase concentrations; Hepatotoxicity See opioid analgesic BW | CS-II |
| Codeine/acetaminophen | Tylenol w/ Codeine #3, Tylenol w/ Codeine #4 | Opioid/nonopioid analgesic combination | Pain | Dizziness, Drowsiness, Nausea, Vomiting, Constipation, Pruritus, Respiratory depression (dose-related) | N/A | Use or D/C of 3A4 inducers, inhibitors, or 2D6 inhibitors requires consideration; Resp. depression & death in children after tonsillectomy/adenoidectomy who are ultra-rapid metabolizers; Hepatotoxicity See opioid analgesic BW | CS-III |
| Naloxone | Narcan Nasal Spray, Zimhi | Opioid antagonist | Opioid overdose | Opioid withdrawal syndrome in opioid-dependent populations, Pain | N/A | N/A | Intranasal: OTC |
| Buprenorphine/naloxone | Suboxone | Partial opioid agonist/opioid antagonist | Opioid use disorder | Opioid withdrawal syndrome in opioid-dependent populations, Constipation, Headache, Diaphoresis | Potentially life-threatening respiratory depression (when combined w/ other CNS & respiratory depressants); Addition of naloxone to buprenorphine reduces the possibility of parenteral misuse by producing opioid withdrawal symptoms when injected | N/A | CS-III |
| Ferrous sulfate | FeroSul, SlowFe | Iron supplement | Iron deficiency anemia | Dark & tarry stools, Nausea, Upset stomach, Constipation (dose-related) | N/A | Accidental overdose of iron is leading cause of fatal poisoning in children under 6 years old | OTC |
| Cyanocobalamin (vitamin B12) | N/A | Water-soluble vitamin | Vitamin B12 deficiency (manifests as macrocytic anemia) | No major side effects | N/A | N/A | PO/SL: OTC |
| Folic acid | N/A | Water-soluble vitamin | Folic acid deficiency (manifests as macrocytic anemia), prevention of neural tube defects in pregnancy | No major side effects | N/A | N/A | OTC |