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PHARMA BLOOD

QuestionAnswer
A condition of chronic excess total body iron caused either by an inherited abnormality of iron absorption or by frequent transfusions to treat certain types of hemolytic disorders Hemochromatosis
A deficiency in serum hemoglobin and erythrocytes in which the erythrocytes are abnormally large . Results from either folate or vitamin B12 deficiency anemia Megaloblastic anemia
A deficiency in serum hemoglobin and erythrocytes in which the erythrocytes are abnormally small . Often caused by iron deficiency Microcytic anemia
An abnormally low number of neutrophils in the blood; patients with neutropenia are susceptible to serious infection Neutropenia
most common type of megaloblastic anemia resulting from deficiency of intrinsic factor, a protein produced by gastric mucosal cells and required for intestinal absorption of vitamin B12 Pernicious anemia
An abnormally low number of platelets in the blood; patients with thrombocytopenia are susceptible to hemorrhage Thrombocytopenia
Required for the biosynthesis of heme and heme-containing proteins , including hemoglobin and myoglobin Uses: iron deficiency anemia Ferrous Sulfate
Chelates excess iron (If the patient has acute iron intoxication Uses: acute iron poisoning , hemachromatosis not adequately treated with phlebotomy Deferoxamine
Cofactor in the transfer of 1-carbon units, a step necessary for the synthesis of DNA Cobalt-containing molecule Produced only by bacteria 2 forms: cyanocobalamin, hydroxocobalamin Vitamin B12
Required for normal DNA synthesis Deficiency during pregnancy increases the risk of neural defects in the fetus Folic Acid
Agonist of erythropoietin receptors expressed by red cell progenitors Uses: anemia associated with chronic renal failure , HIV infection, cancer, and prematurity Epoetin Alfa
A granulocyte colony stimulating factor Accelerates neutrophil recovery and reduces incidence of infection USES: neutropenia assoc. w/ chemotherapy, myelodysplasia, and aplastic anemia, Filgrastim
To regulate the differentiation and maturation of stem cells within the bone marrow Stimulate the bone marrow to produce specific blood cells & help its formation, maturation and function Hematopoic Growth Factors -
DRUGS USED IN COAGULATION DISORDER platelet activator and powerful vasoconstrictor Thromboxane A2
DRUGS USED IN COAGULATION DISORDER a potent endothelium derived vasoconstrictor Endothelin
DRUGS USED IN COAGULATION DISORDER platelet aggregation Adenosine PO4 (ADP):
DRUGS USED IN COAGULATION DISORDER platelet aggregation and vasoconstriction Serotonin:
is the most common cause of acute myocardial infarction, ischemic stroke and limb gangrene Arterial thrombosis
Non-selective, irreversible COX 1 and 2 inhibitor Reduces platelet production of TXA2 , a potent stimulator of platelet aggregation Uses: prevention of arterial thrombosis, inflammatory disorders aspirin
Inhibits Platelet Aggregation By Interfering With (glycoproteinIIb/IIIareceptor) GPIIb/IIIa binding to fibrinogen and other ligands Abciximab
Irreversibly inhibits binding of ADP to platelet receptors , reducing platelet aggregation Clopidogrel
Inhibits phosphodiesterase III and increased cAMP in platelets and blood vessels Inhibits platelet aggregation and causes vasodilation Dipyridamole
Mainly for the prevention and treatment of venous thrombosis (pulmunary embolism & deep vein thrombosis Drugs that inhibits formation of fibrin clots Anticoagulants
also called thrombolytics medications that dissolve blood clots for myocardial infarction, ischemic stroke, or massive pulmunary embolism Converts plasminogen to plasmin Fibrinolytic drugs
Inhibits plasmin and plasmin-streptokinase complex in patients who have received streptokinase Aprotonin
Created by: nixieee
 

 



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