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PUD Dumping Syndrome
| Question | Answer |
|---|---|
| Peptic Ulcer Disease (PUD) | Erosion of stomach/duodenal mucosa when mucosal defenses are impaired by acid/H. pylori |
| Gastric Ulcer | Ulcers in stomach; pain occurs 30-60 min postprandial, not relieved by food; common ages 50-70 |
| Duodenal Ulcer | Most common type; pain occurs 2-3 hrs postprandial or at night, relieved by food; ages 20-50 |
| Stress Ulcer | Acute ulceration after major medical stress (burns, sepsis, head injury); bleeding is main manifestation |
| PUD Symptoms | Dyspepsia (sharp, burning, gnawing pain), epigastric discomfort, nausea, bloating, anorexia |
| PUD Complications | Hemorrhage (most serious), perforation (medical emergency), gastric outlet obstruction |
| Perforation Signs | Sudden sharp abdominal pain, rigid board-like abdomen, guarding, fetal position, peritonitis |
| Hemorrhage Signs | Hematemesis (bright red or coffee-ground), melena (black tarry stools), signs of hypovolemic shock |
| Dumping Syndrome | Rapid gastric emptying of hyperosmolar chyme into small intestine post-gastrectomy/gastric surgery |
| Early Dumping Syndrome | Occurs 30 min postprandial: fullness, weakness, dizziness, palpitations, sweating, diarrhea |
| Late Dumping Syndrome | Occurs 90 min-3 hrs postprandial: hypoglycemia from excessive insulin release, confusion, diaphoresis |
| Dumping Syndrome Management | High-protein, high-fat, low-carb diet; no liquids with meals; lie down after eating |
| Dumping Meds | Acarbose (slows carb absorption), Octreotide SQ (slows GI transit); symptoms often resolve in 6-12 months |
| Gastric Cancer | Adenocarcinoma most common; linked to H. pylori, chronic gastritis; poor prognosis if late diagnosis |
| Early Gastric CA Signs | Dyspepsia, epigastric discomfort relieved by antacids, bloating, mild pain radiating to back |
| Advanced Gastric CA Signs | Nausea/vomiting, palpable epigastric mass, weight loss, fatigue, iron/B12 deficiency anemia |
| Gastric Cancer Treatment | Surgical resection (subtotal/partial gastrectomy), possible chemo/radiation; monthly B12 post-op |