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Osteoporosis
| Question | Answer |
|---|---|
| Osteoporosis | Chronic disease where bone resorption exceeds formation causing fragile bones |
| Osteopenia | Low bone mass precursor to osteoporosis T-score between -1 and -2.5 |
| Bone Remodeling | Constant process of bone resorption by osteoclasts and formation by osteoblasts |
| Bone Mineral Density | Amount of mineral in bone determining strength peaks age 25-30 |
| DXA Scan | Dual-energy X-ray absorptiometry the diagnostic test for osteoporosis |
| T-Score | Result from DXA 0 is healthy, -1 to -2.5 is osteopenia, ≤-2.5 is osteoporosis |
| Postmenopausal Risk | Postmenopausal white women at greatest risk for osteoporosis fractures |
| Key Risk Factors | Low calcium vitamin D smoking alcohol immobility steroids family history |
| Vitamin D Role | Essential for calcium absorption deficiency causes bone softening |
| Nursing Interventions | Educate on calcium vitamin D weight-bearing exercise and fall prevention |
| Bisphosphonates | Drug class like alendronate that prevents osteoclast bone resorption |
| Bisphos Administration | Take on empty stomach with full water remain upright 30 minutes after |
| Bisphos IV Risks | Can cause atrial fibrillation and acute kidney injury monitor renal function |
| Raloxifene (SERM) | Selective Estrogen Receptor Modulator preserves BMD reduces breast cancer risk |
| Osteomalacia | Bone softening from vitamin D deficiency causing pain and bowing |
| Paget's Disease | Disorder with excessive bone remodeling leads to deformity and pain |
| Paget's Symptoms | Bone pain deformity skull enlargement hearing loss pathologic fractures |