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Foodborne Pathogens

PathogenInfection or IntoxicationFoods Commonly AssociatedUnique aspectsDisease Caused
Hepatitis A & E Infection Shellfish from contaminated waters, foods handled by infected food workers, contaminated water Fecal–oral transmission; shed in feces 10-14 days before symptoms; highly contagious; long incubation (15–50 days) Hepatitis (liver inflammation, jaundice, malaise, vomiting)
Norovirus Infection Ready-to-eat foods, produce, shellfish, contaminated beverages (e.g., smoothies) Extremely contagious; spread via vomit, feces, surfaces; leading cause (~90%) of viral gastroenteritis outbreaks Acute viral gastroenteritis (~50% of “stomach flu”)
Toxoplasma gondii Infection (protozoan parasite) Undercooked pork, mutton, venison; contaminated shellfish; cat litter boxes Cats are definitive host; lifelong cysts; severe in immunocompromised and fetus Toxoplasmosis (encephalitis, congenital defects)
Staphylococcus aureus Intoxication (preformed toxin) Foods handled and left at room temp: salads, dairy, meats, picnic foods Heat-stable toxin; humans are major reservoir (skin, nose); animal carriers; rapid onset (30 min or 4–6 hr) Staphylococcal food poisoning
Clostridium perfringens Infection (toxin produced in gut) Meat dishes, gravies, large batches of foods held warm Rapid growth; spores survive cooking; reheating leftovers to 165°F critical; sporulation releases enterotoxin Clostridium perfringens gastroenteritis
Clostridium botulinum (Foodborne) Intoxication (neurotoxin in food) Home-canned foods, baked potatoes, smoked fish, oil-packed foods, low acid foods Most potent toxin known; anaerobic, spore forming; neurotoxin; toxin destroyed by boiling 10 min Botulism (flaccid paralysis, respiratory failure)
Clostridium botulinum (Infant) Infection (toxin produced in gut) Honey, dust, soil Infants <1 year; spores germinate in intestine; implicated in 4% of SIDs in US Infant botulism
Salmonella spp. Infection Undercooked or improperly refrigerated poultry, eggs, meat, unpasteurized milk, produce, pet foods Zoonotic; many serovars; internal egg contamination (S. Enteritidis) Salmonellosis (diarrhea, fever, abdominal pain); Chronic illness: reactive arthritis, Reiter's syndrome
Escherichia coli (ETEC, EPEC) Infection Contaminated food or water Causes traveler’s diarrhea and infant diarrhea Acute diarrheal disease
Shiga Toxin-Produing E. coli (STEC) / E. coli O157:H7 Infection (toxin-mediated damage) Ground beef, unpasteurized juices/milk, leafy greens, sprouts, flour Produces Shiga toxin; very low infectious dose; regulated “BIG 7”; leading cause of acute renal failure in children Hemorrhagic colitis, HUS, TTP
Campylobacter Infection Poultry, unpasteurized milk, contaminated water Microaerophilic; low infectious dose (~500 cells); post-infection complications Campylobacteriosis (diarrhea, fever, cramps); Chronic diseases (reactive arthritis, Reiter’s syndrome, Guillain-Barre)
Listeria monocytogenes Infection Soft cheeses, deli meats, smoked seafood, ice cream, cut melons Psychrotrophic (grows in fridge); long incubation (up to 90 days); high fatality Listeriosis (meningitis, septicemia, fetal loss); high mortality rates
Other notable pathogens Infection or intoxication Rice (B. cereus), seafood (Vibrio), infant formula (Cronobacter), pork (Yersinia) Varies by organism; some grow cold or produce toxins Various GI and systemic illnesses
Created by: abireid
 

 



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